|Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs|
E Brookes, I de Santiago, D Hebenstreit, KJ Morris, T Carroll, SQ Xie, ...
Cell stem cell 10 (2), 157-170, 2012
|Complex multi-enhancer contacts captured by genome architecture mapping|
RA Beagrie, A Scialdone, M Schueler, DCA Kraemer, M Chotalia, SQ Xie, ...
Nature 543 (7646), 519, 2017
|Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1|
KB Meyer, M O’Reilly, K Michailidou, S Carlebur, SL Edwards, JD French, ...
The American Journal of Human Genetics 93 (6), 1046-1060, 2013
|Master regulators of FGFR2 signalling and breast cancer risk|
MNC Fletcher, MAA Castro, X Wang, I De Santiago, M O’Reilly, SF Chin, ...
Nature communications 4, 2464, 2013
|Impact of artifact removal on ChIP quality metrics in ChIP-seq and ChIP-exo data|
TS Carroll, Z Liang, R Salama, R Stark, I de Santiago
Frontiers in genetics 5, 75, 2014
|Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation|
M Ghoussaini, SL Edwards, K Michailidou, S Nord, R Cowper-Sal, ...
Nature communications 5, 4999, 2014
|Regulators of genetic risk of breast cancer identified by integrative network analysis|
MAA Castro, I de Santiago, TM Campbell, C Vaughn, TE Hickey, E Ross, ...
Nature genetics 48 (1), 12, 2016
|Combined image and genomic analysis of high-grade serous ovarian cancer reveals PTEN loss as a common driver event and prognostic classifier|
FC Martins, I de Santiago, A Trinh, J Xian, A Guo, K Sayal, ...
Genome biology 15 (12), 526, 2014
|Eukaryotic gene regulation in three dimensions and its impact on genome evolution|
MM Babu, SC Janga, I de Santiago, A Pombo
Current opinion in genetics & development 18 (6), 571-582, 2008
|Active and poised promoter states drive folding of the extended HoxB locus in mouse embryonic stem cells|
M Barbieri, SQ Xie, ET Triglia, AM Chiariello, S Bianco, I de Santiago, ...
Nature structural & molecular biology 24 (6), 515, 2017
|Accumulated metabolites of hydroxybutyric acid serve as diagnostic and prognostic biomarkers of ovarian high-grade serous carcinomas|
M Hilvo, I De Santiago, P Gopalacharyulu, WD Schmitt, J Budczies, ...
Cancer research 76 (4), 796-804, 2016
|Master regulators of oncogenic KRAS response in pancreatic cancer: an integrative network biology analysis|
S Sivakumar, I de Santiago, L Chlon, F Markowetz
PLoS medicine 14 (1), e1002223, 2017
|FGFR2 risk SNPs confer breast cancer risk by augmenting oestrogen responsiveness|
TM Campbell, MAA Castro, I de Santiago, MNC Fletcher, S Halim, ...
Carcinogenesis 37 (8), 741-750, 2016
|RNA polymerase II primes Polycomb‐repressed developmental genes throughout terminal neuronal differentiation|
C Ferrai, ET Triglia, JR Risner‐Janiczek, T Rito, OJL Rackham, ...
Molecular systems biology 13 (10), 2017
|BaalChIP: Bayesian analysis of allele-specific transcription factor binding in cancer genomes|
I de Santiago, W Liu, K Yuan, M O’Reilly, CSR Chilamakuri, BAJ Ponder, ...
Genome biology 18 (1), 39, 2017
|Immunophenotypes of pancreatic ductal adenocarcinoma: Meta‐analysis of transcriptional subtypes|
I De Santiago, C Yau, L Heij, MR Middleton, F Markowetz, HI Grabsch, ...
International journal of cancer, 2019
|Analysis of ChIP-seq data in R/Bioconductor|
I de Santiago, T Carroll
Chromatin Immunoprecipitation, 195-226, 2018
|Complex multi-enhancer contacts captured by genome architecture mapping, a novel ligation-free approach|
A Pombo, RA Beagrie, A Scialdone, M Schueler, M Chotalia, SQ Xie, ...
The FASEB Journal 30 (1_supplement), 99.3-99.3, 2016
|AB012. S012. Immunophenotypes of pancreatic ductal adenocarcinoma|
I de Santiago, C Yau, M Middleton, M Dustin, F Markowetz, S Sivakumar
Annals of Pancreatic Cancer 1 (4), 2018
|Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation (vol 5, 4999, 2014)|
M Ghoussaini, SL Edwards, K Michailidou, S Nord, RCS Lari, K Desai, ...
Nature Communications 9, 2018