| Design, synthesis, biochemical, and antiviral evaluations of C6 benzyl and C6 biarylmethyl substituted 2-hydroxylisoquinoline-1, 3-diones: dual inhibition against HIV reverse … SKV Vernekar, Z Liu, E Nagy, L Miller, KA Kirby, DJ Wilson, J Kankanala, ... Journal of medicinal chemistry 58 (2), 651-664, 2015 | 133 | 2015 |
| 5′-Silylated 3′-1, 2, 3-triazolyl thymidine analogues as inhibitors of West Nile virus and dengue virus SKV Vernekar, L Qiu, J Zhang, J Kankanala, H Li, RJ Geraghty, Z Wang Journal of medicinal chemistry 58 (9), 4016-4028, 2015 | 81 | 2015 |
| Structure‐guided design affirms inhibitors of hepatitis C virus p7 as a viable class of antivirals targeting virion release TL Foster, GS Thompson, AP Kalverda, J Kankanala, M Bentham, ... Hepatology 59 (2), 408-422, 2014 | 68 | 2014 |
| Design, synthesis, and biological evaluations of hydroxypyridonecarboxylic acids as inhibitors of HIV reverse transcriptase associated RNase H J Kankanala, KA Kirby, F Liu, L Miller, E Nagy, DJ Wilson, MA Parniak, ... Journal of medicinal chemistry 59 (10), 5051-5062, 2016 | 63 | 2016 |
| Isoquinoline-1, 3-diones as selective inhibitors of tyrosyl DNA phosphodiesterase II (TDP2) J Kankanala, C Marchand, M Abdelmalak, H Aihara, Y Pommier, Z Wang Journal of medicinal chemistry 59 (6), 2734-2746, 2016 | 63 | 2016 |
| 3-Hydroxypyrimidine-2,4-dione-5-N-benzylcarboxamides Potently Inhibit HIV-1 Integrase and RNase H B Wu, J Tang, DJ Wilson, AD Huber, MC Casey, J Ji, J Kankanala, J Xie, ... Journal of medicinal chemistry 59 (13), 6136-6148, 2016 | 47 | 2016 |
| Design, synthesis and biological evaluations of N-Hydroxy thienopyrimidine-2, 4-diones as inhibitors of HIV reverse transcriptase-associated RNase H J Kankanala, KA Kirby, AD Huber, MC Casey, DJ Wilson, SG Sarafianos, ... European journal of medicinal chemistry 141, 149-161, 2017 | 43 | 2017 |
| Double-winged 3-hydroxypyrimidine-2, 4-diones: potent and selective inhibition against HIV-1 RNase H with significant antiviral activity SKV Vernekar, J Tang, B Wu, AD Huber, MC Casey, N Myshakina, ... Journal of medicinal chemistry 60 (12), 5045-5056, 2017 | 43 | 2017 |
| Deazaflavin inhibitors of tyrosyl-DNA phosphodiesterase 2 (TDP2) specific for the human enzyme and active against cellular TDP2 C Marchand, M Abdelmalak, J Kankanala, S Huang, E Kiselev, K Fesen, ... ACS chemical biology 11 (7), 1925-1933, 2016 | 40 | 2016 |
| 6-Arylthio-3-hydroxypyrimidine-2, 4-diones potently inhibited HIV reverse transcriptase-associated RNase H with antiviral activity L Wang, J Tang, AD Huber, MC Casey, KA Kirby, DJ Wilson, J Kankanala, ... European journal of medicinal chemistry 156, 652-665, 2018 | 35 | 2018 |
| A combinatorial in silico and cellular approach to identify a new class of compounds that target VEGFR2 receptor tyrosine kinase activity and angiogenesis J Kankanala, AM Latham, AP Johnson, S Homer‐Vanniasinkam, ... British journal of pharmacology 166 (2), 737-748, 2012 | 35 | 2012 |
| 6-Biphenylmethyl-3-hydroxypyrimidine-2, 4-diones potently and selectively inhibited HIV reverse transcriptase-associated RNase H L Wang, J Tang, AD Huber, MC Casey, KA Kirby, DJ Wilson, J Kankanala, ... European journal of medicinal chemistry 156, 680-691, 2018 | 34 | 2018 |
| Triazolopyrimidine and triazolopyridine scaffolds as TDP2 inhibitors CJA Ribeiro, J Kankanala, J Xie, J Williams, H Aihara, Z Wang Bioorganic & medicinal chemistry letters 29 (2), 257-261, 2019 | 29 | 2019 |
| Inhibition of human cytomegalovirus pUL89 terminase subunit blocks virus replication and genome cleavage Y Wang, L Mao, J Kankanala, Z Wang, RJ Geraghty Journal of virology 91 (3), 10.1128/jvi. 02152-16, 2017 | 28 | 2017 |
| Bimetallic (Cu/Pd) catalytic cascade reactions to 3, 3-disubstituted oxindole analogues G Packer, K Lepre, J Kankanala, V Sridharan RSC Advances 4 (7), 3457-3460, 2014 | 27 | 2014 |
| Pharmacophore-based design of novel 3-hydroxypyrimidine-2, 4-dione subtypes as inhibitors of HIV reverse transcriptase-associated RNase H: tolerance of a nonflexible linker J Tang, HT Do, AD Huber, MC Casey, KA Kirby, DJ Wilson, J Kankanala, ... European journal of medicinal chemistry 166, 390-399, 2019 | 26 | 2019 |
| Toward structurally novel and metabolically stable HIV-1 capsid-targeting small molecules SKV Vernekar, RL Sahani, MC Casey, J Kankanala, L Wang, KA Kirby, ... Viruses 12 (4), 452, 2020 | 24 | 2020 |
| 5-Aminothiophene-2, 4-dicarboxamide analogues as hepatitis B virus capsid assembly effectors J Tang, AD Huber, DL Pineda, KN Boschert, JJ Wolf, J Kankanala, J Xie, ... European journal of medicinal chemistry 164, 179-192, 2019 | 23 | 2019 |
| Hydroxypyridonecarboxylic acids as inhibitors of human cytomegalovirus pUL89 endonuclease J Kankanala, Y Wang, RJ Geraghty, Z Wang ChemMedChem 13 (16), 1658-1663, 2018 | 21 | 2018 |
| Receptor tyrosine kinase structure and function in health and disease OA Karpov, GW Fearnley, GA Smith, J Kankanala, MJ McPherson, ... AIMS Biophysics 2 (4), 476-502, 2015 | 21 | 2015 |
