Fabio Cominelli
Fabio Cominelli
Verified email at case.edu
TitleCited byYear
Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies
D Kontoyiannis, M Pasparakis, TT Pizarro, F Cominelli, G Kollias
Immunity 10 (3), 387-398, 1999
12861999
IL-18, a novel immunoregulatory cytokine, is up-regulated in Crohn’s disease: expression and localization in intestinal mucosal cells
TT Pizarro, MH Michie, M Bentz, J Woraratanadharm, MF Smith, E Foley, ...
The Journal of Immunology 162 (11), 6829-6835, 1999
5751999
Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease. A novel mechanism of chronic intestinal inflammation.
V Casini-Raggi, L Kam, YJ Chong, C Fiocchi, TT Pizarro, F Cominelli
The Journal of Immunology 154 (5), 2434-2440, 1995
4321995
Interleukin 1 (IL-1) gene expression, synthesis, and effect of specific IL-1 receptor blockade in rabbit immune complex colitis.
F Cominelli, CC Nast, BD Clark, R Schindler, R Lierena, VE Eysselein, ...
The Journal of clinical investigation 86 (3), 972-980, 1990
3701990
New concepts in the pathophysiology of inflammatory bowel disease
G Bamias, MR Nyce, A Sarah, F Cominelli
Annals of internal medicine 143 (12), 895-904, 2005
3232005
Expression, localization, and functional activity of TL1A, a novel Th1-polarizing cytokine in inflammatory bowel disease
G Bamias, C Martin, M Marini, S Hoang, M Mishina, WG Ross, ...
The Journal of Immunology 171 (9), 4868-4874, 2003
2942003
Probiotics promote gut health through stimulation of epithelial innate immunity
C Pagnini, R Saeed, G Bamias, KO Arseneau, TT Pizarro, F Cominelli
Proceedings of the national academy of sciences 107 (1), 454-459, 2010
2812010
Th1-type responses mediate spontaneous ileitis in a novel murine model of Crohn’s disease
MM Kosiewicz, CC Nast, A Krishnan, J Rivera-Nieves, CA Moskaluk, ...
The Journal of clinical investigation 107 (6), 695-702, 2001
2652001
Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor–induced Crohn's-like inflammatory bowel disease
D Kontoyiannis, G Boulougouris, M Manoloukos, M Armaka, M Apostolaki, ...
Journal of Experimental Medicine 196 (12), 1563-1574, 2002
2512002
The relationship between infliximab treatment and lymphoma in Crohn's disease
SJ Bickston, GR Lichtenstein, KO Arseneau, RB Cohen, F Cominelli
Gastroenterology 117 (6), 1433-1437, 1999
2171999
Recombinant interleukin-1 receptor antagonist blocks the proinflammatory activity of endogenous interleukin-1 in rabbit immune colitis
F Cominelli, CC Nast, A Duchini, M Lee
Gastroenterology 103 (1), 65-71, 1992
2171992
Functional and ethnic association of allele 2 of the interleukin-1 receptor antagonist gene in ulcerative colitis
NA Tountas, V Casini–Raggi, H Yang, FS Di Giovine, M Vecchi, L Kam, ...
Gastroenterology 117 (4), 806-813, 1999
2141999
Localization of intestinal interleukin 1 activity and protein and gene expression to lamina propria cells
KR Youngman, PL Simon, GA West, F Cominelli, D Rachmilewitz, ...
Gastroenterology 104 (3), 749-758, 1993
2021993
TNF-αneutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosis
M Marini, G Bamias, J Rivera-Nieves, CA Moskaluk, SB Hoang, WG Ross, ...
Proceedings of the National Academy of Sciences 100 (14), 8366-8371, 2003
1902003
Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease
M Odashima, G Bamias, J Rivera-Nieves, J Linden, CC Nast, ...
Gastroenterology 129 (1), 26-33, 2005
1802005
Antibody blockade of ICAM-1 and VCAM-1 ameliorates inflammation in the SAMP-1/Yit adoptive transfer model of Crohn's disease in mice
RC Burns, J Rivera-Nieves, CA Moskaluk, S Matsumoto, F Cominelli, ...
Gastroenterology 121 (6), 1428-1436, 2001
1762001
Role of TL1A and its receptor DR3 in two models of chronic murine ileitis
G Bamias, M Mishina, M Nyce, WG Ross, G Kollias, J Rivera-Nieves, ...
Proceedings of the National Academy of Sciences 103 (22), 8441-8446, 2006
1722006
Mouse models for the study of Crohn's disease
TT Pizarro, KO Arseneau, G Bamias, F Cominelli
Trends in molecular medicine 9 (5), 218-222, 2003
1722003
Cytokine-based therapies for Crohn's disease—new paradigms
F Cominelli
New England Journal of Medicine 351 (20), 2045-2048, 2004
1622004
The primary defect in experimental ileitis originates from a nonhematopoietic source
TS Olson, BK Reuter, KGE Scott, MA Morris, XM Wang, LN Hancock, ...
Journal of Experimental Medicine 203 (3), 541-552, 2006
1582006
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