| The SH3 domain--a family of versatile peptide-and protein-recognition module. T Kaneko, L Li, SS Li Frontiers in bioscience: a journal and virtual library 13, 4938, 2008 | 242 | 2008 |
| Ultra-deep tyrosine phosphoproteomics enabled by a phosphotyrosine superbinder Y Bian, L Li, M Dong, X Liu, T Kaneko, K Cheng, H Liu, C Voss, X Cao, ... Nature chemical biology 12 (11), 959-966, 2016 | 166 | 2016 |
| Superbinder SH2 domains act as antagonists of cell signaling T Kaneko, H Huang, X Cao, X Li, C Li, C Voss, SS Sidhu, SSC Li Science signaling 5 (243), ra68-ra68, 2012 | 146 | 2012 |
| Dynamic methylation of Numb by Set8 regulates its binding to p53 and apoptosis GK Dhami, H Liu, M Galka, C Voss, R Wei, K Muranko, T Kaneko, ... Molecular cell 50 (4), 565-576, 2013 | 117 | 2013 |
| Loops govern SH2 domain specificity by controlling access to binding pockets. T Kaneko, H Huang, B Zhao, L Li, H Liu, CK Voss, C Wu, MR Schiller, ... Science signaling 3 (120), ra34, 2010 | 108 | 2010 |
| Phosphotyrosine recognition domains: The typical, the atypical and the versatile T Kaneko, R Joshi, SM Feller, SSC Li Cell Communication and Signaling 10 (1), 32, 2012 | 106 | 2012 |
| Differential regulation of the activity of deleted in liver cancer 1 (DLC1) by tensins controls cell migration and transformation X Cao, C Voss, B Zhao, T Kaneko, SSC Li Proceedings of the National Academy of Sciences 109 (5), 1455-1460, 2012 | 89 | 2012 |
| The human phosphotyrosine signaling network: evolution and hotspots of hijacking in cancer L Li, C Tibiche, C Fu, T Kaneko, MF Moran, MR Schiller, SSC Li, E Wang Genome research 22 (7), 1222-1230, 2012 | 79 | 2012 |
| The spatial transcriptomic landscape of non-small cell lung cancer brain metastasis Q Zhang, R Abdo, C Iosef, T Kaneko, M Cecchini, VK Han, SSC Li Nature Communications 13 (1), 5983, 2022 | 77 | 2022 |
| Structural insight into modest binding of a non-PXXP ligand to the signal transducing adaptor molecule-2 Src homology 3 domain T Kaneko, T Kumasaka, T Ganbe, T Sato, K Miyazawa, N Kitamura, ... Journal of Biological Chemistry 278 (48), 48162, 2003 | 76 | 2003 |
| Structural basis of the substrate subsite and the highly thermal stability of xylanase 10B from Thermotoga maritima MSB8 Ihsanawati, T Kumasaka, T Kaneko, C Morokuma, R Yatsunami, T Sato, ... Proteins: Structure, Function, and Bioinformatics 61 (4), 999-1009, 2005 | 75 | 2005 |
| Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate GM Findlay, MJ Smith, F Lanner, MS Hsiung, GD Gish, E Petsalaki, ... Cell 152 (5), 1008-1020, 2013 | 71 | 2013 |
| Crystal structures of RsbQ, a stress‐response regulator in Bacillus subtilis T Kaneko, N Tanaka, T Kumasaka Protein Science 14 (2), 558-565, 2005 | 70 | 2005 |
| Cell regulation by phosphotyrosine-targeted ubiquitin ligases JA Cooper, T Kaneko, SSC Li Molecular and cellular biology 35 (11), 1886-1897, 2015 | 55 | 2015 |
| Evolving specificity from variability for protein interaction domains T Kaneko, SS Sidhu, SSC Li Trends in biochemical sciences 36 (4), 183-190, 2011 | 55 | 2011 |
| A phosphorylation switch controls the spatiotemporal activation of Rho GTPases in directional cell migration X Cao, T Kaneko, JS Li, AD Liu, C Voss, SSC Li Nature communications 6, 7721, 2015 | 52 | 2015 |
| Epitope-specific antibody responses differentiate COVID-19 outcomes and variants of concern C Voss, S Esmail, X Liu, MJ Knauer, S Ackloo, T Kaneko, L Lowes, ... JCI insight 6 (13), 2021 | 36 | 2021 |
| Flow of portal and hepatic blood in normal and cirrhotic liver T Nakamura, S Nakamura, T Kaneko Nature 190 (4778), 812-813, 1961 | 24 | 1961 |
| Identification and characterization of a large family of superbinding bacterial SH2 domains T Kaneko, PJ Stogios, X Ruan, C Voss, E Evdokimova, T Skarina, ... Nature communications 9 (1), 4549, 2018 | 22 | 2018 |
| Surface Loops in a Single SH2 Domain Are Capable of Encoding the Spectrum of Specificity of the SH2 Family*[S] H Liu, H Huang, C Voss, T Kaneko, WT Qin, S Sidhu, SSC Li Molecular & Cellular Proteomics 18 (2), 372-382, 2019 | 21 | 2019 |
Shawn Shun-Cheng LiProfessor of Biochemistry, Western University, London, Ontario, CanadaVerified email at uwo.ca
