Antioxidants can increase melanoma metastasis in mice K Le Gal, MX Ibrahim, C Wiel, VI Sayin, MK Akula, C Karlsson, MG Dalin, ... Science translational medicine 7 (308), 308re8-308re8, 2015 | 645 | 2015 |
BACH1 stabilization by antioxidants stimulates lung cancer metastasis C Wiel, K Le Gal, MX Ibrahim, CA Jahangir, M Kashif, H Yao, DV Ziegler, ... Cell 178 (2), 330-345. e22, 2019 | 404 | 2019 |
Endoplasmic reticulum calcium release through ITPR2 channels leads to mitochondrial calcium accumulation and senescence C Wiel, H Lallet-Daher, D Gitenay, B Gras, B Le Calvé, A Augert, ... Nature communications 5 (1), 3792, 2014 | 179 | 2014 |
Histone variant H2A. J accumulates in senescent cells and promotes inflammatory gene expression K Contrepois, C Coudereau, BA Benayoun, N Schuler, PF Roux, ... Nature communications 8 (1), 14995, 2017 | 168 | 2017 |
Glutamine links obesity to inflammation in human white adipose tissue P Petrus, S Lecoutre, L Dollet, C Wiel, A Sulen, H Gao, B Tavira, ... Cell metabolism 31 (2), 375-390. e11, 2020 | 162 | 2020 |
Calcium channel ITPR2 and mitochondria–ER contacts promote cellular senescence and aging DV Ziegler, D Vindrieux, D Goehrig, S Jaber, G Collin, A Griveau, C Wiel, ... Nature Communications 12 (1), 720, 2021 | 93 | 2021 |
Targeting Krasg12c‐mutant cancer with a mutation‐specific inhibitor JG Christensen, P Olson, T Briere, C Wiel, MO Bergo Journal of internal medicine 288 (2), 183-191, 2020 | 83 | 2020 |
PLA2R1 mediates tumor suppression by activating JAK2 D Vindrieux, A Augert, CA Girard, D Gitenay, H Lallet-Daher, C Wiel, ... Cancer research 73 (20), 6334-6345, 2013 | 82 | 2013 |
Lysyl oxidase family activity promotes resistance of pancreatic ductal adenocarcinoma to chemotherapy by limiting the intratumoral anticancer drug distribution. B Le Calvé, A Griveau, D Vindrieux, R Maréchal, C Wiel, M Svrcek, J Gout, ... Oncotarget, 2016 | 68 | 2016 |
Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence D Gitenay, C Wiel, H Lallet-Daher, D Vindrieux, S Aubert, L Payen, ... Cell death & disease 5 (2), e1089-e1089, 2014 | 50 | 2014 |
Potassium channel KCNA1 modulates oncogene-induced senescence and transformation H Lallet-Daher, C Wiel, D Gitenay, N Navaratnam, A Augert, B Le Calvé, ... Cancer research 73 (16), 5253-5265, 2013 | 49 | 2013 |
The JAK1/2 inhibitor ruxolitinib delays premature aging phenotypes A Griveau, C Wiel, DV Ziegler, MO Bergo, D Bernard Aging cell 19 (4), e13122, 2020 | 43 | 2020 |
Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes A Griveau, C Wiel, B Le Calvé, DV Ziegler, S Djebali, M Warnier, N Martin, ... Aging Cell 17 (6), e12835, 2018 | 34 | 2018 |
Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis C Wiel, A Augert, DF Vincent, D Gitenay, D Vindrieux, B Le Calvé, V Arfi, ... Cell death & disease 4 (10), e855, 2013 | 33 | 2013 |
A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells X Chen, H Yao, M Kashif, G Revêchon, M Eriksson, J Hu, T Wang, Y Liu, ... Elife 10, e63284, 2021 | 26 | 2021 |
The SCN 9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway M Warnier, JM Flaman, C Chouabe, C Wiel, B Gras, A Griveau, E Blanc, ... Aging Cell 17 (3), e12736, 2018 | 25 | 2018 |
Mitochondria-targeted antioxidants MitoQ and MitoTEMPO do not influence BRAF-driven malignant melanoma and KRAS-driven lung cancer progression in mice K Le Gal, C Wiel, MX Ibrahim, M Henricsson, VI Sayin, MO Bergo Antioxidants 10 (2), 163, 2021 | 21 | 2021 |
KRAS Mutations Impact Clinical Outcome in Metastatic Non-Small Cell Lung Cancer EA Eklund, C Wiel, H Fagman, LM Akyürek, S Raghavan, J Nyman, ... Cancers 14 (9), 2063, 2022 | 19 | 2022 |
Antioxidants promote intestinal tumor progression in mice ZV Zou, K Le Gal, AE El Zowalaty, LE Pehlivanoglu, V Garellick, N Gul, ... Antioxidants 10 (2), 241, 2021 | 18 | 2021 |
The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity L Casares, R Moreno, KX Ali, M Higgins, SD Naidu, G Neill, L Cassin, ... Redox Biology 51, 102291, 2022 | 12 | 2022 |