TJ Ley
TJ Ley
Professor of Medicine and Genetics, Washington University School of Medicine
Verified email at wustl.edu - Homepage
TitleCited byYear
Mutational landscape and significance across 12 major cancer types
C Kandoth, MD McLellan, F Vandin, K Ye, B Niu, C Lu, M Xie, Q Zhang, ...
Nature 502 (7471), 333, 2013
25042013
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
Cancer Genome Atlas Research Network
New England Journal of Medicine 368 (22), 2059-2074, 2013
21332013
Recurring mutations found by sequencing an acute myeloid leukemia genome
ER Mardis, L Ding, DJ Dooling, DE Larson, MD McLellan, K Chen, ...
New England Journal of Medicine 361 (11), 1058-1066, 2009
20232009
DNMT3A Mutations in Acute Myeloid Leukemia
TJ Ley, L Ding, MJ Walter, MD McLellan, T Lamprecht, DE Larson, ...
New England Journal of Medicine 363 (25), 2424-2433, 2010
16702010
Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
L Ding, TJ Ley, DE Larson, CA Miller, DC Koboldt, JS Welch, JK Ritchey, ...
Nature 481 (7382), 506, 2012
16392012
International network of cancer genome projects
International Cancer Genome Consortium
Nature 464 (7291), 993, 2010
14582010
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome
TJ Ley, ER Mardis, L Ding, B Fulton, MD McLellan, K Chen, D Dooling, ...
Nature 456 (7218), 66, 2008
12692008
Lymphocyte-mediated cytotoxicity
JH Russell, TJ Ley
Annual review of immunology 20 (1), 323-370, 2002
12502002
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
J Zhang, L Ding, L Holmfeldt, G Wu, SL Heatley, D Payne-Turner, ...
Nature 481 (7380), 157, 2012
11712012
BreakDancer: an algorithm for high-resolution mapping of genomic structural variation
K Chen, JW Wallis, MD McLellan, DE Larson, JM Kalicki, CS Pohl, ...
Nature methods 6 (9), 677, 2009
11602009
Human T regulatory cells can use the perforin pathway to cause autologous target cell death
WJ Grossman, JW Verbsky, W Barchet, M Colonna, JP Atkinson, TJ Ley
Immunity 21 (4), 589-601, 2004
11152004
Genome remodelling in a basal-like breast cancer metastasis and xenograft
LI Ding, MJ Ellis, S Li, DE Larson, K Chen, JW Wallis, CC Harris, ...
Nature 464 (7291), 999, 2010
11102010
The origin and evolution of mutations in acute myeloid leukemia
JS Welch, TJ Ley, DC Link, CA Miller, DE Larson, DC Koboldt, ...
Cell 150 (2), 264-278, 2012
10952012
Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells
JW Heusel, RL Wesselschmidt, S Shresta, JH Russell, TJ Ley
Cell 76 (6), 977-987, 1994
9291994
Age-related mutations associated with clonal hematopoietic expansion and malignancies
M Xie, C Lu, J Wang, MD McLellan, KJ Johnson, MC Wendl, ...
Nature medicine 20 (12), 1472, 2014
8712014
Whole-genome analysis informs breast cancer response to aromatase inhibition
MJ Ellis, L Ding, D Shen, J Luo, VJ Suman, JW Wallis, BA Van Tine, ...
Nature 486 (7403), 353, 2012
8562012
Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance
X Cao, SF Cai, TA Fehniger, J Song, LI Collins, DR Piwnica-Worms, ...
Immunity 27 (4), 635-646, 2007
7592007
Clonal architecture of secondary acute myeloid leukemia
MJ Walter, D Shen, L Ding, J Shao, DC Koboldt, K Chen, DE Larson, ...
New England Journal of Medicine 366 (12), 1090-1098, 2012
6972012
Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis
A Belaaouaj, R McCarthy, M Baumann, Z Gao, TJ Ley, SN Abraham, ...
Nature medicine 4 (5), 615, 1998
6491998
Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells
WJ Grossman, JW Verbsky, BL Tollefsen, C Kemper, JP Atkinson, TJ Ley
Blood 104 (9), 2840-2848, 2004
5452004
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