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Ramon Hendrickx
Ramon Hendrickx
RIA iMed, AstraZeneca
Verified email at astrazeneca.com
Title
Cited by
Cited by
Year
Identification of novel substrates and structure–activity relationship of cellular uptake mediated by human organic cation transporters 1 and 2
R Hendrickx, JG Johansson, C Lohmann, RM Jenvert, A Blomgren, ...
Journal of medicinal chemistry 56 (18), 7232-7242, 2013
982013
Discovery of a novel oral glucocorticoid receptor modulator (AZD9567) with improved side effect profile
L Ripa, K Edman, M Dearman, G Edenro, R Hendrickx, V Ullah, ...
Journal of Medicinal Chemistry 61 (5), 1785-1799, 2018
662018
Selective nonsteroidal glucocorticoid receptor modulators for the inhaled treatment of pulmonary diseases
M Hemmerling, S Nilsson, K Edman, S Eirefelt, W Russell, R Hendrickx, ...
Journal of Medicinal Chemistry 60 (20), 8591-8605, 2017
542017
Translational model to predict pulmonary pharmacokinetics and efficacy in man for inhaled bronchodilators
R Hendrickx, E Lamm Bergström, DLI Janzén, M Fridén, U Eriksson, ...
CPT: pharmacometrics & systems pharmacology 7 (3), 147-157, 2018
362018
An investigation by means of correlation analysis into the mechanisms of oxidation of aryl methyl sulfides and sulfoxides by dimethyldioxirane in various solvents
P Hanson, RAAJ Hendrickx, JRL Smith
Organic & Biomolecular Chemistry 6 (4), 745-761, 2008
352008
A kinetic investigation, supported by theoretical calculations, of steric and ring strain effects on the oxidation of sulfides and sulfoxides by dimethyldioxirane in acetone
P Hanson, RAAJ Hendrickx, JRL Smith
New Journal of Chemistry 34 (1), 65-84, 2010
262010
Discovery of indazole ethers as novel, potent, non-steroidal glucocorticoid receptor modulators
M Hemmerling, K Edman, M Lepistö, A Eriksson, S Ivanova, J Dahmén, ...
Bioorganic & Medicinal Chemistry Letters 26 (23), 5741-5748, 2016
202016
Solid-state perturbation for solubility improvement: a proof of concept
LE Briggner, R Hendrickx, L Kloo, J Rosdahl, PH Svensson
ChemMedChem 6 (1), 60-62, 2011
182011
Effects of a selective glucocorticoid receptor modulator (AZD9567) versus prednisolone in healthy volunteers: two phase 1, single-blind, randomised controlled trials
TH Myrbäck, S Prothon, K Edman, J Leander, M Hashemi, M Dearman, ...
The Lancet Rheumatology 2 (1), e31-e41, 2020
162020
Characterization of selective and potent JAK1 inhibitors intended for the inhaled treatment of asthma
M Nilsson, M Rhedin, R Hendrickx, S Berglund, A Piras, P Blomgran, ...
Drug design, development and therapy, 2901-2917, 2023
112023
Kinetic studies on the oxidation of aryl methyl sulfides and sulfoxides by dimethyldioxirane; absolute rate constants and activation parameters for 4-nitrophenyl methyl sulfide …
P Hanson, RAAJ Hendrickx, JRL Smith
Organic & Biomolecular Chemistry 6 (4), 762-771, 2008
112008
The photoaddition of pyrroles to arylethenes and arylethynes
M Austin, C Covell, A Gilbert, R Hendrickx
Liebigs Annalen 1997 (5), 943-946, 1997
91997
Selective Janus kinase 1 inhibition resolves inflammation and restores hair growth offering a viable treatment option for alopecia areata
J Mattsson, E Israelsson, K Björhall, LF Yrlid, K Thörn, A Thorén, ...
Skin Health and Disease 3 (3), e209, 2023
42023
Discovery of the potent and selective inhaled janus kinase 1 inhibitor AZD4604 and its preclinical characterization
M Nilsson, K Berggren, S Berglund, S Cerboni, M Collins, G Dahl, ...
Journal of Medicinal Chemistry 66 (19), 13400-13415, 2023
32023
SAT0245 Azd9567: a novel oral selective glucocorticoid receptor modulator, demonstrated to have an improved therapeutic ratio compared to prednisolone in pre-clinical studies …
R Hendrickx, T Hegelund-Myrbäck, M Dearman, S Prothon, G Edenro, ...
Annals of the Rheumatic Diseases 77 (Suppl 2), 984-985, 2018
22018
Identification of AZD9567, an anti-inflammatory glucocorticoid receptor modulator with improved side effect profile
L Ripa, M Dearman, G Edenro, K Edman, R Hendrickx, M Lepisto, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017
12017
Investigating the efficacy of a NaV1. 7 channel blocker on airway sensory nerve activation and cough
SJ Bonvini, F Shala, J Adcock, M Wortley, R Gopalakrishnan, S Francis, ...
European Respiratory Journal 62 (suppl 67), 2023
2023
Profiling the impact of two JAK inhibitors in a pre-clinical model of allergic asthma
J Pinkerton, B Dekkak, D Zervas, T Markou, A Borde, A Cavallin, ...
European Respiratory Journal 56 (suppl 64), 2020
2020
SAT0251 Selective glucocorticoid receptor modulator shows potent anti-inflammatory effect with improved metabolic profile in a phase i study supported by in vitro data
TH Myrbäck, S Prothon, M Dearman, G Edenro, J Leander, M Hashemi, ...
Annals of the Rheumatic Diseases 77 (Suppl 2), 987-987, 2018
2018
Next generation glucocorticoid receptor modulators
K Edman, G Belfield, M Dearman, G Edenro, S Geschwindner, ...
Endocrine Abstracts 54, 2018
2018
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