A tarantula-venom peptide antagonizes the TRPA1 nociceptor ion channel by binding to the S1–S4 gating domain J Gui, B Liu, G Cao, AM Lipchik, M Perez, Z Dekan, M Mobli, NL Daly, ... Current Biology 24 (5), 473-483, 2014 | 73 | 2014 |
HAT1 coordinates histone production and acetylation via H4 promoter binding JJ Gruber, B Geller, AM Lipchik, J Chen, AA Salahudeen, AN Ram, ... Molecular cell 75 (4), 711-724. e5, 2019 | 60 | 2019 |
Time-resolved luminescence detection of spleen tyrosine kinase activity through terbium sensitization AM Lipchik, LL Parker Analytical chemistry 85 (5), 2582-2588, 2013 | 48 | 2013 |
A peptide biosensor for detecting intracellular Abl kinase activity using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry EA Placzek, MP Plebanek, AM Lipchik, SR Kidd, LL Parker Analytical biochemistry 397 (1), 73-78, 2010 | 44 | 2010 |
KINATEST-ID: a pipeline to develop phosphorylation-dependent terbium sensitizing kinase assays AM Lipchik, M Perez, S Bolton, V Dumrongprechachan, SB Ouellette, ... Journal of the American Chemical Society 137 (7), 2484-2494, 2015 | 39 | 2015 |
A peptide-based biosensor assay to detect intracellular Syk kinase activation and inhibition AM Lipchik, RL Killins, RL Geahlen, LL Parker Biochemistry 51 (38), 7515-7524, 2012 | 27 | 2012 |
Multicolored, Tb3+-Based Antibody-Free Detection of Multiple Tyrosine Kinase Activities AM Lipchik, M Perez, W Cui, LL Parker Analytical chemistry 87 (15), 7555-7558, 2015 | 25 | 2015 |
A cancer-associated RNA polymerase III identity drives robust transcription and expression of snaR-A noncoding RNA K Van Bortle, DP Marciano, Q Liu, T Chou, AM Lipchik, S Gollapudi, ... Nature communications 13 (1), 3007, 2022 | 15 | 2022 |
Akt2 inhibits the activation of NFAT in lymphocytes by modulating calcium release from intracellular stores VA Martin, WH Wang, AM Lipchik, LL Parker, Y He, S Zhang, ZY Zhang, ... Cellular signalling 24 (5), 1064-1073, 2012 | 14 | 2012 |
Substrate binding to Src: A new perspective on tyrosine kinase substrate recognition from NMR and molecular dynamics MK Joshi, RA Burton, H Wu, AM Lipchik, BP Craddock, H Mo, LL Parker, ... Protein Science 29 (2), 350-359, 2020 | 12 | 2020 |
Chromatin remodeling in response to BRCA2-crisis JJ Gruber, J Chen, B Geller, N Jäger, AM Lipchik, G Wang, AW Kurian, ... Cell reports 28 (8), 2182-2193. e6, 2019 | 9 | 2019 |
Tyrosine kinase biosensors and methods of use LL Parker, AM Lipchik, SC Bolton US Patent 9,499,854, 2016 | 6 | 2016 |
A Quantitative Proteomics-Based Competition Binding Assay to Characterize pITAM–Protein Interactions L Hu, L Yang, AM Lipchik, RL Geahlen, LL Parker, WA Tao Analytical chemistry 85 (10), 5071-5077, 2013 | 5 | 2013 |
Acetyl-click screening platform identifies small-molecule inhibitors of histone acetyltransferase 1 (HAT1) JD Gaddameedi, T Chou, BS Geller, A Rangarajan, TA Swaminathan, ... Journal of Medicinal Chemistry 66 (8), 5774-5801, 2023 | 4* | 2023 |
Methods for detecting enzyme activity using fluorescence lifetime imaging LL Parker, JMK Irudayarsaj, AM Lipchik, NP Damayanti US Patent 10,023,902, 2018 | 3 | 2018 |
Tyrosine kinase biosensors and methods of use LL Parker, AM Lipchik, SC Bolton US Patent 10,150,984, 2018 | 2 | 2018 |
The IgG Antibody Paradox in Insulin Resistance: Pathogenic and Therapeutic A Lipchik, S Lee, JP Annes, MP Snyder Journal of the Endocrine Society 5 (Suppl 1), A443, 2021 | 1 | 2021 |
Tyrosine kinase inhibitors induce mitochondrial dysfunction during cardiomyocyte differentiation through alteration of GATA4-mediated networks Q Liu, H Wu, QJ Luo, C Jiang, Z Duren, K Van Bortle, M Zhao, B Zhao, ... bioRxiv, 2020.05. 04.077024, 2020 | 1 | 2020 |
Author Spotlight: Developing Acetyl-Click Assay for HAT1 Inhibitor Screening S Rajkumar, D Dixon, AM Lipchik, JJ Gruber JoVE (Journal of Visualized Experiments), e66054, 2024 | | 2024 |
An Acetyl-Click Chemistry Assay to Measure Histone Acetyltransferase 1 Acetylation. S Rajkumar, D Dixon, AM Lipchik, JJ Gruber Journal of Visualized Experiments: Jove, 2024 | | 2024 |