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Kenneth P. Olive
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Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
KP Olive, MA Jacobetz, CJ Davidson, A Gopinathan, D McIntyre, ...
Science 324 (5933), 1457-1461, 2009
35052009
Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma
AD Rhim, PE Oberstein, DH Thomas, ET Mirek, CF Palermo, SA Sastra, ...
Cancer cell 25 (6), 735-747, 2014
19732014
Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome
KP Olive, DA Tuveson, ZC Ruhe, B Yin, NA Willis, RT Bronson, D Crowley, ...
Cell 119 (6), 847-860, 2004
14772004
Stromal biology and therapy in pancreatic cancer
A Neesse, P Michl, KK Frese, C Feig, N Cook, MA Jacobetz, MP Lolkema, ...
Gut 60 (6), 861-868, 2011
8902011
Cysteine depletion induces pancreatic tumor ferroptosis in mice
MA Badgley, DM Kremer, HC Maurer, KE DelGiorno, HJ Lee, V Purohit, ...
Science 368 (6486), 85-89, 2020
7692020
The differential effects of mutant p53 alleles on advanced murine lung cancer
EL Jackson, KP Olive, DA Tuveson, R Bronson, D Crowley, M Brown, ...
Cancer research 65 (22), 10280-10288, 2005
5972005
Pancreatic cancer: why is it so hard to treat?
PE Oberstein, KP Olive
Therapeutic advances in gastroenterology 6 (4), 321-337, 2013
4162013
β2 adrenergic-neurotrophin feedforward loop promotes pancreatic cancer
BW Renz, R Takahashi, T Tanaka, M Macchini, Y Hayakawa, Z Dantes, ...
Cancer cell 33 (1), 75-90. e7, 2018
3642018
The use of targeted mouse models for preclinical testing of novel cancer therapeutics
KP Olive, DA Tuveson
Clinical Cancer Research 12 (18), 5277-5287, 2006
3022006
Surface-enhanced resonance Raman scattering nanostars for high-precision cancer imaging
S Harmsen, R Huang, MA Wall, H Karabeber, JM Samii, M Spaliviero, ...
Science translational medicine 7 (271), 271ra7-271ra7, 2015
2822015
Multivalent small-molecule pan-RAS inhibitors
ME Welsch, A Kaplan, JM Chambers, ME Stokes, PH Bos, A Zask, ...
Cell 168 (5), 878-889. e29, 2017
2562017
Dclk1 defines quiescent pancreatic progenitors that promote injury-induced regeneration and tumorigenesis
CB Westphalen, Y Takemoto, T Tanaka, M Macchini, Z Jiang, BW Renz, ...
Cell stem cell 18 (4), 441-455, 2016
2232016
Cholinergic signaling via muscarinic receptors directly and indirectly suppresses pancreatic tumorigenesis and cancer stemness
BW Renz, T Tanaka, M Sunagawa, R Takahashi, Z Jiang, M Macchini, ...
Cancer discovery 8 (11), 1458-1473, 2018
1862018
Germline Brca2 heterozygosity promotes KrasG12D-driven carcinogenesis in a murine model of familial pancreatic cancer
F Skoulidis, LD Cassidy, V Pisupati, JG Jonasson, H Bjarnason, ...
Cancer cell 18 (5), 499-509, 2010
1812010
Experimental microdissection enables functional harmonisation of pancreatic cancer subtypes
C Maurer, SR Holmstrom, J He, P Laise, T Su, A Ahmed, H Hibshoosh, ...
Gut 68 (6), 1034-1043, 2019
1662019
Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts
S Bhattacharjee, F Hamberger, A Ravichandra, M Miller, A Nair, S Affo, ...
The Journal of clinical investigation 131 (11), 2021
1622021
The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer
KA Michaelis, MA Norgard, X Zhu, PR Levasseur, S Sivagnanam, ...
Nature communications 10 (1), 4682, 2019
1522019
Genetically engineered mouse models of pancreatic cancer
CB Westphalen, KP Olive
The Cancer Journal 18 (6), 502-510, 2012
1492012
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis
DM Kremer, BS Nelson, L Lin, EL Yarosz, CJ Halbrook, SA Kerk, ...
Nature communications 12 (1), 4860, 2021
1382021
Current and emerging therapies in metastatic pancreatic cancer
GA Manji, KP Olive, YM Saenger, P Oberstein
Clinical Cancer Research 23 (7), 1670-1678, 2017
1372017
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