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Goutham Narla - Chief, Division of Genetic Medicine Associate Professor, Department of Medicine
Goutham Narla - Chief, Division of Genetic Medicine Associate Professor, Department of Medicine
Verified email at med.umich.edu - Homepage
Title
Cited by
Cited by
Year
KLF6, a candidate tumor suppressor gene mutated in prostate cancer
G Narla, KE Heath, HL Reeves, D Li, LE Giono, AC Kimmelman, ...
Science 294 (5551), 2563-2566, 2001
5982001
All roads lead to PP 2A: exploiting the therapeutic potential of this phosphatase
J Sangodkar, CC Farrington, K McClinch, MD Galsky, DB Kastrinsky, ...
The FEBS journal 283 (6), 1004-1024, 2016
3102016
microRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial–mesenchymal transition
A Parikh, C Lee, P Joseph, S Marchini, A Baccarini, V Kolev, C Romualdi, ...
Nature communications 5 (1), 2977, 2014
2832014
A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk
G Narla, A DiFeo, HL Reeves, DJ Schaid, J Hirshfeld, E Hod, A Katz, ...
Cancer research 65 (4), 1213-1222, 2005
2672005
Kruppel-like factor 6 (KLF6) is a tumor-suppressor gene frequently inactivated in colorectal cancer
HL Reeves, G Narla, O Ogunbiyi, AI Haq, A Katz, S Benzeno, E Hod, ...
Gastroenterology 126 (4), 1090-1103, 2004
2222004
The Kruppel-like factor 6 genotype is associated with fibrosis in nonalcoholic fatty liver disease
L Miele, G Beale, G Patman, V Nobili, J Leathart, A Grieco, M Abate, ...
Gastroenterology 135 (1), 282-291. e1, 2008
2192008
Krüppel-like factor-6 promotes preadipocyte differentiation through histone deacetylase 3-dependent repression of DLK1
D Li, S Yea, S Li, Z Chen, G Narla, M Banck, J Laborda, S Tan, ...
Journal of Biological Chemistry 280 (29), 26941-26952, 2005
2162005
Cyclin-dependent kinase inhibition by the KLF6 tumor suppressor protein through interaction with cyclin D1
S Benzeno, G Narla, J Allina, GZ Cheng, HL Reeves, MS Banck, JA Odin, ...
Cancer research 64 (11), 3885-3891, 2004
2032004
Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread
G Narla, A DiFeo, S Yao, A Banno, E Hod, HL Reeves, RF Qiao, ...
Cancer Research 65 (13), 5761-5768, 2005
2022005
Mutations in capillary morphogenesis gene-2 result in the allelic disorders juvenile hyaline fibromatosis and infantile systemic hyalinosis
O Dowling, A Difeo, MC Ramirez, T Tukel, G Narla, L Bonafe, H Kayserili, ...
The American Journal of Human Genetics 73 (4), 957-966, 2003
1902003
Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth
J Sangodkar, A Perl, R Tohme, J Kiselar, DB Kastrinsky, N Zaware, ...
The Journal of clinical investigation 127 (6), 2081-2090, 2017
1802017
Therapeutic targeting of PP2A
CM O’Connor, A Perl, D Leonard, J Sangodkar, G Narla
The international journal of biochemistry & cell biology 96, 182-193, 2018
1762018
Frequent inactivation of the tumor suppressor Kruppel‐like factor 6 (KLF6) in hepatocellular carcinoma
S Kremer‐Tal, HL Reeves, G Narla, SN Thung, M Schwartz, A Difeo, ...
Hepatology 40 (5), 1047-1052, 2004
1732004
The role of KLF6 and its splice variants in cancer therapy
A DiFeo, JA Martignetti, G Narla
Drug Resistance Updates 12 (1-2), 1-7, 2009
1702009
Kruppel-like transcription factor 6 regulates inflammatory macrophage polarization
D Date, R Das, G Narla, DI Simon, MK Jain, GH Mahabeleshwar
Journal of Biological Chemistry 289 (15), 10318-10329, 2014
1662014
The apolipoprotein(a) gene is regulated by sex hormones and acute–phase inducers in YAC transgenic mice
KA Frazer, G Narla, JL Zhang, EM Rubin
Nature genetics 9 (4), 424-431, 1995
1501995
PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells
O Kauko, CM O’Connor, E Kulesskiy, J Sangodkar, A Aakula, S Izadmehr, ...
Science translational medicine 10 (450), eaaq1093, 2018
1392018
KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis
G Narla, A DiFeo, Y Fernandez, S Dhanasekaran, F Huang, J Sangodkar, ...
The Journal of clinical investigation 118 (8), 2711-2721, 2008
1362008
Roles of KLF6 and KLF6-SV1 in ovarian cancer progression and intraperitoneal dissemination
A DiFeo, G Narla, J Hirshfeld, O Camacho-Vanegas, J Narla, SL Rose, ...
Clinical Cancer Research 12 (12), 3730-3739, 2006
1342006
Ras promotes growth by alternative splicing-mediated inactivation of the KLF6 tumor suppressor in hepatocellular carcinoma
S Yea, G Narla, X Zhao, R Garg, S Tal–Kremer, E Hod, A Villanueva, ...
Gastroenterology 134 (5), 1521-1531, 2008
1252008
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