Deamidation and isomerization liability analysis of 131 clinical-stage antibodies X Lu, RP Nobrega, H Lynaugh, T Jain, K Barlow, T Boland, ... MAbs 11 (1), 45-57, 2019 | 103 | 2019 |
Sub-millisecond time-resolved SAXS using a continuous-flow mixer and X-ray microbeam R Graceffa, RP Nobrega, RA Barrea, SV Kathuria, S Chakravarthy, ... Journal of synchrotron radiation 20 (6), 820-825, 2013 | 71 | 2013 |
Minireview: Structural insights into early folding events using continuous‐flow time‐resolved small‐angle X‐ray scattering SV Kathuria, L Guo, R Graceffa, R Barrea, RP Nobrega, CR Matthews, ... Biopolymers 95 (8), 550-558, 2011 | 66 | 2011 |
Clusters of isoleucine, leucine, and valine side chains define cores of stability in high‐energy states of globular proteins: Sequence determinants of structure and stability SV Kathuria, YH Chan, RP Nobrega, A Özen, CR Matthews Protein Science 25 (3), 662-675, 2016 | 65 | 2016 |
Microsecond barrier-limited chain collapse observed by time-resolved FRET and SAXS SV Kathuria, C Kayatekin, R Barrea, E Kondrashkina, R Graceffa, L Guo, ... Journal of molecular biology 426 (9), 1980-1994, 2014 | 60 | 2014 |
Rapid assessment of oxidation via middle-down LCMS correlates with methionine side-chain solvent-accessible surface area for 121 clinical stage monoclonal antibodies R Yang, T Jain, H Lynaugh, RP Nobrega, X Lu, T Boland, I Burnina, T Sun, ... MAbs 9 (4), 646-653, 2017 | 58 | 2017 |
Networks of electrostatic and hydrophobic interactions modulate the complex folding free energy surface of a designed βα protein S Basak, RP Nobrega, D Tavella, LM Deveau, N Koga, R Tatsumi-Koga, ... Proceedings of the National Academy of Sciences 116 (14), 6806-6811, 2019 | 34 | 2019 |
Advances in turbulent mixing techniques to study microsecond protein folding reactions SV Kathuria, A Chan, R Graceffa, R Paul Nobrega, C Robert Matthews, ... Biopolymers 99 (11), 888-896, 2013 | 34 | 2013 |
Modulation of frustration in folding by sequence permutation RP Nobrega, K Arora, SV Kathuria, R Graceffa, RA Barrea, L Guo, ... Proceedings of the National Academy of Sciences 111 (29), 10562-10567, 2014 | 27 | 2014 |
Understanding ForteBio’s sensors for high-throughput kinetic and epitope screening for purified antibodies and yeast culture supernatant Y Yu, S Mitchell, H Lynaugh, M Brown, RP Nobrega, X Zhi, T Sun, I Caffry, ... Journal of Biomolecular Screening 21 (1), 88-95, 2016 | 20 | 2016 |
Atomistic structural ensemble refinement reveals non-native structure stabilizes a sub-millisecond folding intermediate of CheY J Shi, RP Nobrega, C Schwantes, SV Kathuria, O Bilsel, CR Matthews, ... Scientific reports 7 (1), 44116, 2017 | 15 | 2017 |
Complementary techniques enhance the quality and scope of information obtained from SAXS D Lambright, AW Malaby, SV Kathuria, RP Nobrega, O Bilsel, ... ACA Trans, 1-12, 2013 | 10 | 2013 |
Database-Centric Method for Automated High-Throughput Deconvolution and Analysis of Kinetic Antibody Screening Data RP Nobrega, M Brown, C Williams, C Sumner, P Estep, I Caffry, Y Yu, ... SLAS TECHNOLOGY: Translating Life Sciences Innovation 22 (5), 547-556, 2017 | | 2017 |
Early Folding Biases in the Folding Free-Energy Surface of βα-Repeat Proteins: A Dissertation RP Nobrega | | 2014 |
Advances in turbulent mixing techniques to study... SV Kathuria, A Chan, R Graceffa, RP Nobrega, CR Matthews, SV Kathuria, ... Biopolymers 99 (11), 0 | | |