Nigel O'Neil
Nigel O'Neil
Research Associate, University of British Columbia
Verified email at - Homepage
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iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human
D Bergamaschi, Y Samuels, NJ O'Neil, G Trigiante, T Crook, JK Hsieh, ...
Nature genetics 33 (2), 162-167, 2003
Synthetic lethality and cancer
NJ O'Neil, ML Bailey, P Hieter
Nature Reviews Genetics 18 (10), 613-623, 2017
RTEL1 maintains genomic stability by suppressing homologous recombination
LJ Barber, JL Youds, JD Ward, MJ McIlwraith, NJ O'Neil, MIR Petalcorin, ...
Cell 135 (2), 261-271, 2008
Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes
M Le Gallo, AJ O'Hara, ML Rudd, ME Urick, NF Hansen, NJ O'Neil, ...
Nature genetics 44 (12), 1310-1315, 2012
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours
H Xu, M Di Antonio, S McKinney, V Mathew, B Ho, NJ O’Neil, ND Santos, ...
Nature communications 8 (1), 1-18, 2017
RTEL-1 enforces meiotic crossover interference and homeostasis
JL Youds, DG Mets, MJ McIlwraith, JS Martin, JD Ward, NJ ONeil, ...
Science 327 (5970), 1254-1258, 2010
MinION-based long-read sequencing and assembly extends the Caenorhabditis elegans reference genome
JR Tyson, NJ O'Neil, M Jain, HE Olsen, P Hieter, TP Snutch
Genome research 28 (2), 266-274, 2018
DOG-1 Is the Caenorhabditis elegans BRIP1/FANCJ Homologue and Functions in Interstrand Cross-Link Repair
JL Youds, LJ Barber, JD Ward, SJ Collis, NJ O'Neil, SJ Boulton, AM Rose
Molecular and cellular biology 28 (5), 1470-1479, 2008
The use of functional genomics in C. elegans for studying human development and disease
PE Kuwabara, N O'neil
Journal of inherited metabolic disease 24 (2), 127-138, 2001
TILLING is an effective reverse genetics technique for Caenorhabditis elegans
EJ Gilchrist, NJ O'Neil, AM Rose, MC Zetka, GW Haughn
BMC genomics 7 (1), 1-16, 2006
Homologous Recombination Is Required for Genome Stability in the Absence of DOG-1 in Caenorhabditis elegans
JL Youds, NJ O'Neil, AM Rose
Genetics 173 (2), 697-708, 2006
Synthetic lethality of cohesins with PARPs and replication fork mediators
JL McLellan, NJ O'Neil, I Barrett, E Ferree, DM Van Pel, K Ushey, ...
PLoS genetics 8 (3), e1002574, 2012
Glioblastoma Cells Containing Mutations in the Cohesin Component STAG2 Are Sensitive to PARP InhibitionSTAG2 Mutation and PARP Inhibition in Glioblastoma Cells
ML Bailey, NJ O'Neil, DM van Pel, DA Solomon, T Waldman, P Hieter
Molecular cancer therapeutics 13 (3), 724-732, 2014
Joint Molecule Resolution Requires the Redundant Activities of MUS-81 and XPF-1 during Caenorhabditis elegans Meiosis
NJ O'Neil, JS Martin, JL Youds, JD Ward, MIR Petalcorin, AM Rose, ...
PLoS genetics 9 (7), e1003582, 2013
Identification and analysis of internal promoters in Caenorhabditis elegans operons
P Huang, ED Pleasance, JS Maydan, R Hunt-Newbury, NJ O’Neil, A Mah, ...
Genome research 17 (10), 1478-1485, 2007
The sterol modifying enzyme LET-767 is essential for growth, reproduction and development in Caenorhabditis elegans
LM Kuervers, CL Jones, NJ O'neil, DL Baillie
Molecular Genetics and Genomics 270 (2), 121-131, 2003
Nucleotide excision repair and the degradation of RNA pol II by the Caenorhabditis elegans XPA and Rsp5 orthologues, RAD-3 and WWP-1
JW Astin, NJ O’Neil, PE Kuwabara
DNA repair 7 (2), 267-280, 2008
Synthetic Lethal Genetic Interactions That Decrease Somatic Cell Proliferation in Caenorhabditis elegans Identify the Alternative RFCCTF18 as a Candidate …
J McLellan, N O'Neil, S Tarailo, J Stoepel, J Bryan, A Rose, P Hieter
Molecular biology of the cell 20 (24), 5306-5313, 2009
Lethal mutations defining 112 complementation groups in a 4.5 Mb sequenced region of Caenorhabditis elegans chromosome III
HI Stewart, NJ O'Neil, DL Janke, NW Franz, HM Chamberlin, AM Howell, ...
Molecular and General Genetics MGG 260 (2), 280-288, 1998
RNA-mediated interference as a tool for identifying drug targets
NJ O’Neil, RL Martin, ML Tomlinson, MR Jones, A Coulson, PE Kuwabara
American Journal of Pharmacogenomics 1 (1), 45-53, 2001
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