Dimitris Athineos
Dimitris Athineos
The Beatson Institute for Cancer Research
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A complex secretory program orchestrated by the inflammasome controls paracrine senescence
JC Acosta, A Banito, T Wuestefeld, A Georgilis, P Janich, JP Morton, ...
Nature cell biology 15 (8), 978-990, 2013
Myc deletion rescues Apc deficiency in the small intestine
OJ Sansom, VS Meniel, V Muncan, TJ Phesse, JA Wilkins, KR Reed, ...
Nature 446 (7136), 676-679, 2007
Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer
JP Morton, P Timpson, SA Karim, RA Ridgway, D Athineos, B Doyle, ...
Proceedings of the National Academy of Sciences 107 (1), 246-251, 2010
Modulating the therapeutic response of tumours to dietary serine and glycine starvation
ODK Maddocks, D Athineos, EC Cheung, P Lee, T Zhang, ...
Nature 544 (7650), 372-376, 2017
ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation
KB Myant, P Cammareri, EJ McGhee, RA Ridgway, DJ Huels, JB Cordero, ...
Cell stem cell 12 (6), 761-773, 2013
Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death
G Ichim, J Lopez, SU Ahmed, N Muthalagu, E Giampazolias, ME Delgado, ...
Molecular cell 57 (5), 860-872, 2015
Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling
GH Ashton, JP Morton, K Myant, TJ Phesse, RA Ridgway, V Marsh, ...
Developmental cell 19 (2), 259-269, 2010
LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest
JP Morton, NB Jamieson, SA Karim, D Athineos, RA Ridgway, C Nixon, ...
Gastroenterology 139 (2), 586-597. e6, 2010
TIGAR is required for efficient intestinal regeneration and tumorigenesis
EC Cheung, D Athineos, P Lee, RA Ridgway, W Lambie, C Nixon, ...
Developmental cell 25 (5), 463-477, 2013
Dasatinib inhibits the development of metastases in a mouse model of pancreatic ductal adenocarcinoma
JP Morton, SA Karim, K Graham, P Timpson, N Jamieson, D Athineos, ...
Gastroenterology 139 (1), 292-303, 2010
Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium
SE Reid, EJ Kay, LJ Neilson, AT Henze, J Serneels, EJ McGhee, ...
The EMBO journal 36 (16), 2373-2389, 2017
CRISPR/Cas9-mediated Trp53 and Brca2 knockout to generate improved murine models of ovarian high-grade serous carcinoma
J Walton, J Blagih, D Ennis, E Leung, S Dowson, M Farquharson, ...
Cancer research 76 (20), 6118-6129, 2016
Serine one-carbon catabolism with formate overflow
J Meiser, S Tumanov, O Maddocks, CF Labuschagne, D Athineos, ...
Science advances 2 (10), e1601273, 2016
Activation by c-Myc of transcription by RNA polymerases I, II and III
SGE Roberts, ROJ Weinzierl, RJ White, N Gomez-Roman, ...
Biochemical Society Symposia 73, 141-154, 2006
Genetic Dissection of Differential Signaling Threshold Requirements for the Wnt/β-Catenin Pathway In Vivo
M Buchert, D Athineos, HE Abud, ZD Burke, MC Faux, MS Samuel, ...
PLoS genetics 6 (1), e1000816, 2010
The role of MIZ-1 in MYC-dependent tumorigenesis
KE Wiese, S Walz, B von Eyss, E Wolf, D Athineos, O Sansom, M Eilers
Cold Spring Harbor perspectives in medicine 3 (12), a014290, 2013
Cyclin D2–cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss
AM Cole, K Myant, KR Reed, RA Ridgway, D Athineos, GR Van den Brink, ...
Cancer research 70 (20), 8149-8158, 2010
Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma
P Cammareri, AM Rose, DF Vincent, J Wang, A Nagano, S Libertini, ...
Nature communications 7 (1), 1-14, 2016
B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver
KR Reed, D Athineos, VS Meniel, JA Wilkins, RA Ridgway, ZD Burke, ...
Proceedings of the National Academy of Sciences 105 (48), 18919-18923, 2008
Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers
P Carotenuto, M Fassan, R Pandolfo, A Lampis, C Vicentini, L Cascione, ...
Gut 66 (7), 1268-1277, 2017
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