| A complex secretory program orchestrated by the inflammasome controls paracrine senescence JC Acosta, A Banito, T Wuestefeld, A Georgilis, P Janich, JP Morton, ... Nature cell biology 15 (8), 978-990, 2013 | 1316 | 2013 |
| Myc deletion rescues Apc deficiency in the small intestine OJ Sansom, VS Meniel, V Muncan, TJ Phesse, JA Wilkins, KR Reed, ... Nature 446 (7136), 676-679, 2007 | 622 | 2007 |
| Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer JP Morton, P Timpson, SA Karim, RA Ridgway, D Athineos, B Doyle, ... Proceedings of the National Academy of Sciences 107 (1), 246-251, 2010 | 606 | 2010 |
| Modulating the therapeutic response of tumours to dietary serine and glycine starvation ODK Maddocks, D Athineos, EC Cheung, P Lee, T Zhang, ... Nature 544 (7650), 372-376, 2017 | 334 | 2017 |
| ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation KB Myant, P Cammareri, EJ McGhee, RA Ridgway, DJ Huels, JB Cordero, ... Cell stem cell 12 (6), 761-773, 2013 | 328 | 2013 |
| Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death G Ichim, J Lopez, SU Ahmed, N Muthalagu, E Giampazolias, ME Delgado, ... Molecular cell 57 (5), 860-872, 2015 | 284 | 2015 |
| Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling GH Ashton, JP Morton, K Myant, TJ Phesse, RA Ridgway, V Marsh, ... Developmental cell 19 (2), 259-269, 2010 | 181 | 2010 |
| LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest JP Morton, NB Jamieson, SA Karim, D Athineos, RA Ridgway, C Nixon, ... Gastroenterology 139 (2), 586-597. e6, 2010 | 168 | 2010 |
| TIGAR is required for efficient intestinal regeneration and tumorigenesis EC Cheung, D Athineos, P Lee, RA Ridgway, W Lambie, C Nixon, ... Developmental cell 25 (5), 463-477, 2013 | 165 | 2013 |
| Dasatinib inhibits the development of metastases in a mouse model of pancreatic ductal adenocarcinoma JP Morton, SA Karim, K Graham, P Timpson, N Jamieson, D Athineos, ... Gastroenterology 139 (1), 292-303, 2010 | 140 | 2010 |
| Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium SE Reid, EJ Kay, LJ Neilson, AT Henze, J Serneels, EJ McGhee, ... The EMBO journal 36 (16), 2373-2389, 2017 | 131 | 2017 |
| CRISPR/Cas9-mediated Trp53 and Brca2 knockout to generate improved murine models of ovarian high-grade serous carcinoma J Walton, J Blagih, D Ennis, E Leung, S Dowson, M Farquharson, ... Cancer research 76 (20), 6118-6129, 2016 | 126 | 2016 |
| Serine one-carbon catabolism with formate overflow J Meiser, S Tumanov, O Maddocks, CF Labuschagne, D Athineos, ... Science advances 2 (10), e1601273, 2016 | 97 | 2016 |
| Activation by c-Myc of transcription by RNA polymerases I, II and III SGE Roberts, ROJ Weinzierl, RJ White, N Gomez-Roman, ... Biochemical Society Symposia 73, 141-154, 2006 | 96 | 2006 |
| Genetic Dissection of Differential Signaling Threshold Requirements for the Wnt/β-Catenin Pathway In Vivo M Buchert, D Athineos, HE Abud, ZD Burke, MC Faux, MS Samuel, ... PLoS genetics 6 (1), e1000816, 2010 | 91 | 2010 |
| The role of MIZ-1 in MYC-dependent tumorigenesis KE Wiese, S Walz, B von Eyss, E Wolf, D Athineos, O Sansom, M Eilers Cold Spring Harbor perspectives in medicine 3 (12), a014290, 2013 | 86 | 2013 |
| Cyclin D2–cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss AM Cole, K Myant, KR Reed, RA Ridgway, D Athineos, GR Van den Brink, ... Cancer research 70 (20), 8149-8158, 2010 | 81 | 2010 |
| Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma P Cammareri, AM Rose, DF Vincent, J Wang, A Nagano, S Libertini, ... Nature communications 7 (1), 1-14, 2016 | 74 | 2016 |
| B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver KR Reed, D Athineos, VS Meniel, JA Wilkins, RA Ridgway, ZD Burke, ... Proceedings of the National Academy of Sciences 105 (48), 18919-18923, 2008 | 69 | 2008 |
| Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers P Carotenuto, M Fassan, R Pandolfo, A Lampis, C Vicentini, L Cascione, ... Gut 66 (7), 1268-1277, 2017 | 67 | 2017 |
