|Rapid whole-genome sequencing of Mycobacterium tuberculosis isolates directly from clinical samples|
AC Brown, JM Bryant, K Einer-Jensen, J Holdstock, DT Houniet, ...
Journal of clinical microbiology 53 (7), 2230-2237, 2015
|Design and validation of specific inhibitors of 17β-hydroxysteroid dehydrogenases for therapeutic application in breast and prostate cancer, and in endometriosis|
JM Day, HJ Tutill, A Purohit, MJ Reed
Endocrine-Related Cancer 15 (3), 665-692, 2008
|17β‐hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone‐dependent breast cancer|
JM Day, PA Foster, HJ Tutill, MFC Parsons, SP Newman, SK Chander, ...
International journal of cancer 122 (9), 1931-1940, 2008
|E-ring modified steroids as novel potent inhibitors of 17β-hydroxysteroid dehydrogenase type 1|
DS Fischer, GM Allan, C Bubert, N Vicker, A Smith, HJ Tutill, A Purohit, ...
Journal of medicinal chemistry 48 (18), 5749-5770, 2005
|Modification of estrone at the 6, 16, and 17 positions: novel potent inhibitors of 17β-hydroxysteroid dehydrogenase type 1|
GM Allan, HR Lawrence, J Cornet, C Bubert, DS Fischer, N Vicker, ...
Journal of medicinal chemistry 49 (4), 1325-1345, 2006
|Novel and potent 17β-hydroxysteroid dehydrogenase type 1 inhibitors|
HR Lawrence, N Vicker, GM Allan, A Smith, MF Mahon, HJ Tutill, ...
Journal of medicinal chemistry 48 (8), 2759-2762, 2005
|The role of 17β-hydroxysteroid dehydrogenases in modulating the activity of 2-methoxyestradiol in breast cancer cells|
SP Newman, CR Ireson, HJ Tutill, JM Day, MFC Parsons, MP Leese, ...
Cancer research 66 (1), 324-330, 2006
|Whole-genome enrichment and sequencing of Chlamydia trachomatisdirectly from clinical samples|
MT Christiansen, AC Brown, S Kundu, HJ Tutill, R Williams, JR Brown, ...
BMC infectious diseases 14 (1), 591, 2014
|The development of steroid sulfatase inhibitors for hormone‐dependent cancer therapy|
JM Day, A Purohit, HJ Tutill, PA Foster, LWL Woo, BVL Potter, MJ Reed
Annals of the New York Academy of Sciences 1155 (1), 80-87, 2009
|Novel inhibitors of 17β-hydroxysteroid dehydrogenase type 1: Templates for design|
GM Allan, N Vicker, HR Lawrence, HJ Tutill, JM Day, M Huchet, ...
Bioorganic & medicinal chemistry 16 (8), 4438-4456, 2008
|Detection of low frequency multi-drug resistance and novel putative maribavir resistance in immunocompromised pediatric patients with cytomegalovirus|
CJ Houldcroft, JM Bryant, DP Depledge, BK Margetts, J Simmonds, ...
Frontiers in microbiology 7, 1317, 2016
|Focused libraries of 16‐substituted estrone derivatives and modified E‐ring steroids: inhibitors of 17▀‐hydroxysteroid dehydrogenase type 1|
N Vicker, HR Lawrence, GM Allan, C Bubert, A Smith, HJ Tutill, A Purohit, ...
ChemMedChem: Chemistry Enabling Drug Discovery 1 (4), 464-481, 2006
|Islands of linkage in an ocean of pervasive recombination reveals two-speed evolution of human cytomegalovirus genomes|
F Lassalle, DP Depledge, MB Reeves, AC Brown, MT Christiansen, ...
Virus evolution 2 (1), 2016
|17β-Hydroxysteroid dehydrogenase Type 1 and Type 2: Association between mRNA expression and activity in cell lines|
JM Day, HJ Tutill, SP Newman, A Purohit, HR Lawrence, N Vicker, ...
Molecular and cellular endocrinology 248 (1-2), 246-249, 2006
|The regulation and inhibition of 17β-hydroxysteroid dehydrogenase in breast cancer|
A Purohit, HJ Tutill, JM Day, SK Chander, HR Lawrence, GM Allan, ...
Molecular and cellular endocrinology 248 (1-2), 199-203, 2006
|Novel, potent inhibitors of 17β-hydroxysteroid dehydrogenase type 1|
GM Allan, C Bubert, N Vicker, A Smith, HJ Tutill, A Purohit, MJ Reed, ...
Molecular and cellular endocrinology 248 (1-2), 204-207, 2006
|Human cytomegalovirus haplotype reconstruction reveals high diversity due to superinfection and evidence of within-host recombination|
J Cudini, S Roy, CJ Houldcroft, JM Bryant, DP Depledge, H Tutill, P Veys, ...
Proceedings of the National Academy of Sciences 116 (12), 5693-5698, 2019
|Low Prevalence of Conjunctival Infection with Chlamydia trachomatis in a Treatment-Na´ve Trachoma-Endemic Region of the Solomon Islands|
RMR Butcher, O Sokana, K Jack, CK Macleod, ME Marks, E Kalae, L Sui, ...
PLoS neglected tropical diseases 10 (9), e0004863, 2016
|17▀-hydroxysteroid dehydrogenase inhibitors.|
JM Day, HJ Tutill, A Purohit
Minerva endocrinologica 35 (2), 87-108, 2010
|The design of novel 17β-hydroxysteroid dehydrogenase type 3 inhibitors|
N Vicker, CM Sharland, WB Heaton, AMR Gonzalez, HV Bailey, A Smith, ...
Molecular and cellular endocrinology 301 (1-2), 259-265, 2009