Helena Tutill
Helena Tutill
Research Assistant, UCL
Verified email at
Cited by
Cited by
Evaluating the effects of SARS-CoV-2 spike mutation D614G on transmissibility and pathogenicity
E Volz, V Hill, JT McCrone, A Price, D Jorgensen, ┴ O’Toole, J Southgate, ...
Cell 184 (1), 64-75. e11, 2021
Rapid whole-genome sequencing of Mycobacterium tuberculosis isolates directly from clinical samples
AC Brown, JM Bryant, K Einer-Jensen, J Holdstock, DT Houniet, ...
Journal of clinical microbiology 53 (7), 2230-2237, 2015
Design and validation of specific inhibitors of 17β-hydroxysteroid dehydrogenases for therapeutic application in breast and prostate cancer, and in endometriosis
JM Day, HJ Tutill, A Purohit, MJ Reed
Endocrine-related cancer 15 (3), 665-692, 2008
17β‐hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone‐dependent breast cancer
JM Day, PA Foster, HJ Tutill, MFC Parsons, SP Newman, SK Chander, ...
International journal of cancer 122 (9), 1931-1940, 2008
Human cytomegalovirus haplotype reconstruction reveals high diversity due to superinfection and evidence of within-host recombination
J Cudini, S Roy, CJ Houldcroft, JM Bryant, DP Depledge, H Tutill, P Veys, ...
Proceedings of the National Academy of Sciences 116 (12), 5693-5698, 2019
E-ring modified steroids as novel potent inhibitors of 17β-hydroxysteroid dehydrogenase type 1
DS Fischer, GM Allan, C Bubert, N Vicker, A Smith, HJ Tutill, A Purohit, ...
Journal of medicinal chemistry 48 (18), 5749-5770, 2005
Modification of estrone at the 6, 16, and 17 positions: novel potent inhibitors of 17β-hydroxysteroid dehydrogenase type 1
GM Allan, HR Lawrence, J Cornet, C Bubert, DS Fischer, N Vicker, ...
Journal of medicinal chemistry 49 (4), 1325-1345, 2006
Whole-genome enrichment and sequencing of Chlamydia trachomatisdirectly from clinical samples
MT Christiansen, AC Brown, S Kundu, HJ Tutill, R Williams, JR Brown, ...
BMC infectious diseases 14, 1-11, 2014
Novel and potent 17β-hydroxysteroid dehydrogenase type 1 inhibitors
HR Lawrence, N Vicker, GM Allan, A Smith, MF Mahon, HJ Tutill, ...
Journal of medicinal chemistry 48 (8), 2759-2762, 2005
Islands of linkage in an ocean of pervasive recombination reveals two-speed evolution of human cytomegalovirus genomes
F Lassalle, DP Depledge, MB Reeves, AC Brown, MT Christiansen, ...
Virus evolution 2 (1), vew017, 2016
Detection of low frequency multi-drug resistance and novel putative maribavir resistance in immunocompromised pediatric patients with cytomegalovirus
CJ Houldcroft, JM Bryant, DP Depledge, BK Margetts, J Simmonds, ...
Frontiers in Microbiology 7, 1317, 2016
The role of 17β-hydroxysteroid dehydrogenases in modulating the activity of 2-methoxyestradiol in breast cancer cells
SP Newman, CR Ireson, HJ Tutill, JM Day, MFC Parsons, MP Leese, ...
Cancer research 66 (1), 324-330, 2006
Genomic investigations of unexplained acute hepatitis in children
S Morfopoulou, S Buddle, OE Torres Montaguth, L Atkinson, ...
Nature 617 (7961), 564-573, 2023
The development of steroid sulfatase inhibitors for hormone‐dependent cancer therapy
JM Day, A Purohit, HJ Tutill, PA Foster, LWL Woo, BVL Potter, MJ Reed
Annals of the New York Academy of Sciences 1155 (1), 80-87, 2009
Novel inhibitors of 17β-hydroxysteroid dehydrogenase type 1: Templates for design
GM Allan, N Vicker, HR Lawrence, HJ Tutill, JM Day, M Huchet, ...
Bioorganic & medicinal chemistry 16 (8), 4438-4456, 2008
Focused libraries of 16‐substituted estrone derivatives and modified E‐ring steroids: inhibitors of 17▀‐hydroxysteroid dehydrogenase type 1
N Vicker, HR Lawrence, GM Allan, C Bubert, A Smith, HJ Tutill, A Purohit, ...
ChemMedChem: Chemistry Enabling Drug Discovery 1 (4), 464-481, 2006
The regulation and inhibition of 17β-hydroxysteroid dehydrogenase in breast cancer
A Purohit, HJ Tutill, JM Day, SK Chander, HR Lawrence, GM Allan, ...
Molecular and cellular endocrinology 248 (1-2), 199-203, 2006
17β-Hydroxysteroid dehydrogenase Type 1 and Type 2: Association between mRNA expression and activity in cell lines
JM Day, HJ Tutill, SP Newman, A Purohit, HR Lawrence, N Vicker, ...
Molecular and cellular endocrinology 248 (1-2), 246-249, 2006
Novel, potent inhibitors of 17β-hydroxysteroid dehydrogenase type 1
GM Allan, C Bubert, N Vicker, A Smith, HJ Tutill, A Purohit, MJ Reed, ...
Molecular and cellular endocrinology 248 (1-2), 204-207, 2006
Low Prevalence of Conjunctival Infection with Chlamydia trachomatis in a Treatment-Na´ve Trachoma-Endemic Region of the Solomon Islands
RMR Butcher, O Sokana, K Jack, CK Macleod, ME Marks, E Kalae, L Sui, ...
PLoS neglected tropical diseases 10 (9), e0004863, 2016
The system can't perform the operation now. Try again later.
Articles 1–20