|Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo|
LM Butler, DB Agus, HI Scher, B Higgins, A Rose, C Cordon-Cardo, ...
Cancer research 60 (18), 5165-5170, 2000
|The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin|
LM Butler, X Zhou, WS Xu, HI Scher, RA Rifkind, PA Marks, VM Richon
Proceedings of the National Academy of Sciences 99 (18), 11700-11705, 2002
|Androgen receptor inhibits estrogen receptor-α activity and is prognostic in breast cancer|
AA Peters, G Buchanan, C Ricciardelli, T Bianco-Miotto, MM Centenera, ...
Cancer research 69 (15), 6131-6140, 2009
|Targeting the androgen receptor: improving outcomes for castration-resistant prostate cancer|
HI Scher, G Buchanan, W Gerald, LM Butler, WD Tilley
Endocrine-related cancer 11 (3), 459-476, 2004
|Dual roles of PARP-1 promote cancer growth and progression|
MJ Schiewer, JF Goodwin, S Han, JC Brenner, MA Augello, JL Dean, ...
Cancer discovery 2 (12), 1134-1149, 2012
|Discovery of circulating microRNAs associated with human prostate cancer using a mouse model of disease|
LA Selth, S Townley, JL Gillis, AM Ochnik, K Murti, RJ Macfarlane, KN Chi, ...
International Journal of Cancer 131 (3), 652-661, 2012
|The histone deacetylase inhibitor, CBHA, inhibits growth of human neuroblastoma xenografts in vivo, alone and synergistically with all-trans retinoic acid|
DC Coffey, MC Kutko, RD Glick, LM Butler, G Heller, RA Rifkind, PA Marks, ...
Cancer research 61 (9), 3591-3594, 2001
|Therapeutic response to CDK4/6 inhibition in breast cancer defined by ex vivo analyses of human tumors|
JL Dean, AK McClendon, TE Hickey, LM Butler, WD Tilley, AK Witkiewicz, ...
Cell cycle 11 (14), 2756-2761, 2012
|Inhibition of transformed cell growth and induction of cellular differentiation by pyroxamide, an inhibitor of histone deacetylase|
LM Butler, Y Webb, DB Agus, B Higgins, TR Tolentino, MC Kutko, ...
Clinical cancer research 7 (4), 962-970, 2001
|Minireview: the contribution of different androgen receptor domains to receptor dimerization and signaling|
MM Centenera, JM Harris, WD Tilley, LM Butler
Molecular endocrinology 22 (11), 2373-2382, 2008
|Global levels of specific histone modifications and an epigenetic gene signature predict prostate cancer progression and development|
T Bianco-Miotto, K Chiam, G Buchanan, S Jindal, TK Day, M Thomas, ...
Cancer Epidemiology and Prevention Biomarkers 19 (10), 2611-2622, 2010
|Maximizing the therapeutic potential of HSP90 inhibitors|
LM Butler, R Ferraldeschi, HK Armstrong, MM Centenera, P Workman
Molecular cancer research 13 (11), 1445-1451, 2015
|Peptidomimetic targeting of critical androgen receptor–coregulator interactions in prostate cancer|
P Ravindranathan, TK Lee, L Yang, MM Centenera, L Butler, WD Tilley, ...
Nature communications 4 (1), 1-11, 2013
|Circulating microRNAs predict biochemical recurrence in prostate cancer patients|
LA Selth, SL Townley, AG Bert, PD Stricker, PD Sutherland, LG Horvath, ...
British journal of cancer 109 (3), 641-650, 2013
|Control of Androgen Receptor Signaling in Prostate Cancer by the Cochaperone Small Glutamine–Rich Tetratricopeptide Repeat Containing Protein α|
G Buchanan, C Ricciardelli, JM Harris, J Prescott, ZCL Yu, L Jia, ...
Cancer research 67 (20), 10087-10096, 2007
|Suberoylanilide hydroxamic acid (vorinostat) represses androgen receptor expression and acts synergistically with an androgen receptor antagonist to inhibit prostate cancer …|
DL Marrocco, WD Tilley, T Bianco-Miotto, A Evdokiou, HI Scher, ...
Molecular cancer therapeutics 6 (1), 51-60, 2007
|Disruption of androgen receptor signaling by synthetic progestins may increase risk of developing breast cancer|
SN Birrell, LM Butler, JM Harris, G Buchanan, WD Tilley
The FASEB Journal 21 (10), 2285-2293, 2007
|Evidence for efficacy of new Hsp90 inhibitors revealed by ex vivo culture of human prostate tumors|
MM Centenera, JL Gillis, AR Hanson, S Jindal, RA Taylor, GP Risbridger, ...
Clinical Cancer Research 18 (13), 3562-3570, 2012
|Ex vivo culture of human prostate tissue and drug development|
MM Centenera, GV Raj, KE Knudsen, WD Tilley, LM Butler
Nature reviews Urology 10 (8), 483-487, 2013
|Targeting cell cycle and hormone receptor pathways in cancer|
CES Comstock, MA Augello, JF Goodwin, R De Leeuw, MJ Schiewer, ...
Oncogene 32 (48), 5481-5491, 2013