Edwin Chapman
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Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25
J Blasi, ER Chapman, E Link, T Binz, S Yamasaki, P De Camilli, ...
Nature 365 (6442), 160-163, 1993
SV2 is the protein receptor for botulinum neurotoxin A
M Dong, F Yeh, WH Tepp, C Dean, EA Johnson, R Janz, ER Chapman
Science 312 (5773), 592-596, 2006
Botulinum neurotoxin C1 blocks neurotransmitter release by means of cleaving HPC‐1/syntaxin.
J Blasi, ER Chapman, S Yamasaki, T Binz, H Niemann, R Jahn
The EMBO journal 12 (12), 4821-4828, 1993
Synaptotagmin: A Ca 2+ sensor that triggers exocytosis?
ER Chapman
Nature Reviews Molecular Cell Biology 3 (7), 498-508, 2002
How does synaptotagmin trigger neurotransmitter release?
ER Chapman
Annu. Rev. Biochem. 77, 615-641, 2008
Synaptobrevin binding to synaptophysin: a potential mechanism for controlling the exocytotic fusion machine.
L Edelmann, PI Hanson, ER Chapman, R Jahn
The EMBO journal 14 (2), 224-231, 1995
Ca2+ Regulates the Interaction between Synaptotagmin and Syntaxin 1 (∗)
ER Chapman, PI Hanson, S An, R Jahn
Journal of Biological Chemistry 270 (40), 23667-23671, 1995
Reconstitution of Ca2+-regulated membrane fusion by synaptotagmin and SNAREs
WC Tucker, T Weber, ER Chapman
Science 304 (5669), 435-438, 2004
The t-SNAREs syntaxin 1 and SNAP-25 are present on organelles that participate in synaptic vesicle recycling.
C Walch-Solimena, J Blasi, L Edelmann, ER Chapman, GF Von Mollard, ...
The Journal of cell biology 128 (4), 637-645, 1995
PIP 2 increases the speed of response of synaptotagmin and steers its membrane-penetration activity toward the plasma membrane
J Bai, WC Tucker, ER Chapman
Nature structural & molecular biology 11 (1), 36-44, 2004
Synaptophysin regulates the kinetics of synaptic vesicle endocytosis in central neurons
SE Kwon, ER Chapman
Neuron 70 (5), 847-854, 2011
SNAP-25, a t-SNARE which binds to both syntaxin and synaptobrevin via domains that may form coiled coils.
ER Chapman, S An, N Barton, R Jahn
Journal of Biological Chemistry 269 (44), 27427-27432, 1994
Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells
M Dong, DA Richards, MC Goodnough, WH Tepp, EA Johnson, ...
The Journal of cell biology 162 (7), 1293-1303, 2003
Transmembrane segments of syntaxin line the fusion pore of Ca2+-triggered exocytosis
X Han, CT Wang, J Bai, ER Chapman, MB Jackson
science 304 (5668), 289-292, 2004
Synaptotagmin modulation of fusion pore kinetics in regulated exocytosis of dense-core vesicles
CT Wang, R Grishanin, CA Earles, PY Chang, TFJ Martin, ER Chapman, ...
science 294 (5544), 1111-1115, 2001
Kinetics of synaptotagmin responses to Ca2+ and assembly with the core SNARE complex onto membranes
AF Davis, J Bai, D Fasshauer, MJ Wolowick, JL Lewis, ER Chapman
Neuron 24 (2), 363-376, 1999
Direct interaction of a Ca2+-binding loop of synaptotagmin with lipid bilayers
ER Chapman, AF Davis
Journal of Biological Chemistry 273 (22), 13995-14001, 1998
Synaptotagmin-mediated bending of the target membrane is a critical step in Ca2+-regulated fusion
E Hui, CP Johnson, J Yao, FM Dunning, ER Chapman
Cell 138 (4), 709-721, 2009
Calcium-dependent interaction of the cytoplasmic region of synaptotagmin with membranes. Autonomous function of a single C2-homologous domain.
ER Chapman, R Jahn
Journal of Biological Chemistry 269 (8), 5735-5741, 1994
A Novel Function for the Second C2 Domain of Synaptotagmin: Ca2+-TRIGGERED DIMERIZATION (∗)
ER Chapman, S An, JM Edwardson, R Jahn
Journal of Biological Chemistry 271 (10), 5844-5849, 1996
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