Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes CC Robertson, JRJ Inshaw, S Onengut-Gumuscu, WM Chen, ... Nature genetics 53 (7), 962-971, 2021 | 183 | 2021 |
Polygenic inheritance, GWAS, polygenic risk scores, and the search for functional variants DJM Crouch, WF Bodmer Proceedings of the National Academy of Sciences 117 (32), 18924-18933, 2020 | 154 | 2020 |
Genetic variants predisposing most strongly to type 1 diabetes diagnosed under age 7 years lie near candidate genes that function in the immune system and in pancreatic β-cells JRJ Inshaw, AJ Cutler, DJM Crouch, LS Wicker, JA Todd Diabetes Care 43 (1), 169-177, 2020 | 88 | 2020 |
Genetics of the human face: Identification of large-effect single gene variants DJM Crouch, B Winney, WP Koppen, WJ Christmas, K Hutnik, T Day, ... Proceedings of the National Academy of Sciences 115 (4), E676-E685, 2018 | 83 | 2018 |
Childhood body size directly increases type 1 diabetes risk based on a lifecourse Mendelian randomization approach TG Richardson, DJM Crouch, GM Power, F Morales-Berstein, ... Nature communications 13 (1), 2337, 2022 | 44 | 2022 |
Incorporating non-genetic risk factors and behavioural modifications into risk prediction models for colorectal cancer JM Yarnall, DJM Crouch, CM Lewis Cancer epidemiology 37 (3), 324-329, 2013 | 40 | 2013 |
Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells … RC Ferreira, X Castro Dopico, JJ Oliveira, DB Rainbow, JH Yang, ... Frontiers in Immunology 10, 2606, 2019 | 35 | 2019 |
Genes predict village of origin in rural Europe C O'dushlaine, R McQuillan, ME Weale, DJM Crouch, Å Johansson, ... European journal of human genetics 18 (11), 1269-1270, 2010 | 35 | 2010 |
Analysis of overlapping genetic association in type 1 and type 2 diabetes JRJ Inshaw, C Sidore, F Cucca, MI Stefana, DJM Crouch, MI McCarthy, ... Diabetologia 64, 1342-1347, 2021 | 30 | 2021 |
REGENT: a risk assessment and classification algorithm for genetic and environmental factors DJM Crouch, GHM Goddard, CM Lewis European Journal of Human Genetics 21 (1), 109-111, 2013 | 16 | 2013 |
Genetic regulation of RNA splicing in human pancreatic islets G Atla, S Bonās-Guarch, M Cuenca-Ardura, A Beucher, DJM Crouch, ... Genome biology 23 (1), 196, 2022 | 15 | 2022 |
Enhanced genetic analysis of type 1 diabetes by selecting variants on both effect size and significance, and by integration with autoimmune thyroid disease DJM Crouch, JRJ Inshaw, CC Robertson, JY Zhang, WM Chen, ... BioRxiv, 2021.02. 05.429962, 2021 | 12 | 2021 |
Statistical aspects of evolution under natural selection, with implications for the advantage of sexual reproduction DJM Crouch Journal of Theoretical Biology 431, 79-86, 2017 | 9 | 2017 |
Somatic selection of poorly differentiating variant stem cell clones could be a key to human ageing WF Bodmer, DJM Crouch Journal of Theoretical Biology 489, 110153, 2020 | 8 | 2020 |
Inferring separate parental admixture components in unknown DNA samples using autosomal SNPs DJM Crouch, ME Weale European journal of human genetics 20 (12), 1283-1289, 2012 | 5 | 2012 |
Extending non-negative matrix factorisation to 3D registered data WP Koppen, WJ Christmas, DJM Crouch, WF Bodmer, JV Kittler 2016 International Conference on Biometrics (ICB), 1-8, 2016 | 3 | 2016 |
Evolution by natural selection is a scientific law and not just a theory DJM Crouch, WF Bodmer Academia Biology 2 (1), 2024 | 1 | 2024 |
Evolutionary perspectives on cancer and aging WF Bodmer, DJM Crouch New Horizons in Evolution, 97-115, 2021 | 1 | 2021 |
Inferring ancestral and biogeographic origin using genome-wide SNP data D Crouch King's College London (University of London), 2013 | | 2013 |
Tu1904 Towards Individualised Risk Prediction for Crohn's Disease K Taylor, NJ Prescott, SH Anderson, PM Irving, SL West, DJ Crouch, ... Gastroenterology 5 (142), S-874, 2012 | | 2012 |