|Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes|
CC Robertson, JRJ Inshaw, S Onengut-Gumuscu, WM Chen, ...
Nature genetics 53 (7), 962-971, 2021
|Polygenic inheritance, GWAS, polygenic risk scores, and the search for functional variants|
DJM Crouch, WF Bodmer
Proceedings of the National Academy of Sciences 117 (32), 18924-18933, 2020
|Genetics of the human face: Identification of large-effect single gene variants|
DJM Crouch, B Winney, WP Koppen, WJ Christmas, K Hutnik, T Day, ...
Proceedings of the National Academy of Sciences 115 (4), E676-E685, 2018
|Genetic variants predisposing most strongly to type 1 diabetes diagnosed under age 7 years lie near candidate genes that function in the immune system and in pancreatic β-cells|
JRJ Inshaw, AJ Cutler, DJM Crouch, LS Wicker, JA Todd
Diabetes Care 43 (1), 169-177, 2020
|Incorporating non-genetic risk factors and behavioural modifications into risk prediction models for colorectal cancer|
JM Yarnall, DJM Crouch, CM Lewis
Cancer epidemiology 37 (3), 324-329, 2013
|Genes predict village of origin in rural Europe|
C O'dushlaine, R McQuillan, ME Weale, DJM Crouch, Å Johansson, ...
European journal of human genetics 18 (11), 1269-1270, 2010
|Chronic Immune Activation in Systemic Lupus Erythematosus and the Autoimmune PTPN22 Trp620 Risk Allele Drive the Expansion of FOXP3+ Regulatory T Cells …|
RC Ferreira, X Castro Dopico, JJ Oliveira, DB Rainbow, JH Yang, ...
Frontiers in immunology 10, 2606, 2019
|Childhood body size directly increases type 1 diabetes risk based on a lifecourse Mendelian randomization approach|
TG Richardson, DJM Crouch, GM Power, F Morales-Berstein, ...
Nature communications 13 (1), 2337, 2022
|Analysis of overlapping genetic association in type 1 and type 2 diabetes|
JRJ Inshaw, C Sidore, F Cucca, MI Stefana, DJM Crouch, MI McCarthy, ...
Diabetologia 64, 1342-1347, 2021
|REGENT: a risk assessment and classification algorithm for genetic and environmental factors|
DJM Crouch, GHM Goddard, CM Lewis
European Journal of Human Genetics 21 (1), 109-111, 2013
|Enhanced genetic analysis of type 1 diabetes by selecting variants on both effect size and significance, and by integration with autoimmune thyroid disease|
DJM Crouch, JRJ Inshaw, CC Robertson, JY Zhang, WM Chen, ...
BioRxiv, 2021.02. 05.429962, 2021
|Statistical aspects of evolution under natural selection, with implications for the advantage of sexual reproduction|
Journal of Theoretical Biology 431, 79-86, 2017
|Genetic regulation of RNA splicing in human pancreatic islets|
G Atla, S Bonās-Guarch, M Cuenca-Ardura, A Beucher, DJM Crouch, ...
Genome Biology 23 (1), 196, 2022
|Inferring separate parental admixture components in unknown DNA samples using autosomal SNPs|
DJM Crouch, ME Weale
European journal of human genetics 20 (12), 1283-1289, 2012
|Somatic selection of poorly differentiating variant stem cell clones could be a key to human ageing|
WF Bodmer, DJM Crouch
Journal of Theoretical Biology 489, 110153, 2020
|Extending non-negative matrix factorisation to 3D registered data|
WP Koppen, WJ Christmas, DJM Crouch, WF Bodmer, JV Kittler
2016 International Conference on Biometrics (ICB), 1-8, 2016
|Evolutionary perspectives on cancer and aging|
WF Bodmer, DJM Crouch
New Horizons in Evolution, 97-115, 2021
|Inferring ancestral and biogeographic origin using genome-wide SNP data|
King's College London (University of London), 2013
|Tu1904 Towards Individualised Risk Prediction for Crohn's Disease|
K Taylor, NJ Prescott, SH Anderson, PM Irving, SL West, DJ Crouch, ...
Gastroenterology 5 (142), S-874, 2012