In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity GM Lynn, R Laga, PA Darrah, AS Ishizuka, AJ Balaci, AE Dulcey, ... Nature biotechnology 33 (11), 1201-1210, 2015 | 418 | 2015 |
Protection against malaria at 1 year and immune correlates following PfSPZ vaccination AS Ishizuka, KE Lyke, A DeZure, AA Berry, TL Richie, FH Mendoza, ... Nature medicine 22 (6), 614-623, 2016 | 373 | 2016 |
Redox catalysis on “naked” silver nanoparticles G Merga, R Wilson, G Lynn, BH Milosavljevic, D Meisel The Journal of Physical Chemistry C 111 (33), 12220-12226, 2007 | 279 | 2007 |
Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy G Zhu, GM Lynn, O Jacobson, K Chen, Y Liu, H Zhang, Y Ma, F Zhang, ... Nature communications 8 (1), 1-15, 2017 | 272 | 2017 |
Peptide–TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens GM Lynn, C Sedlik, F Baharom, Y Zhu, RA Ramirez-Valdez, VL Coble, ... Nature biotechnology 38 (3), 320-332, 2020 | 251 | 2020 |
Intravenous nanoparticle vaccination generates stem-like TCF1+ neoantigen-specific CD8+ T cells F Baharom, RA Ramirez-Valdez, KKS Tobin, H Yamane, CA Dutertre, ... Nature immunology 22 (1), 41-52, 2021 | 133 | 2021 |
Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling KM Quinn, DE Zak, A Costa, A Yamamoto, K Kastenmuller, BJ Hill, ... The Journal of clinical investigation 125 (3), 1129-1146, 2015 | 96 | 2015 |
Systemic vaccination induces CD8+ T cells and remodels the tumor microenvironment F Baharom, RA Ramirez-Valdez, A Khalilnezhad, S Khalilnezhad, ... Cell 185 (23), 4317-4332. e15, 2022 | 78 | 2022 |
Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies WB Williams, RR Meyerhoff, RJ Edwards, H Li, K Manne, NI Nicely, ... Cell 184 (11), 2955-2972. e25, 2021 | 65 | 2021 |
Thermoresponsive polymer nanoparticles co-deliver RSV F trimers with a TLR-7/8 adjuvant JR Francica, GM Lynn, R Laga, MG Joyce, TJ Ruckwardt, KM Morabito, ... Bioconjugate Chemistry 27 (10), 2372-2385, 2016 | 58 | 2016 |
Oncolytic herpes simplex virus immunotherapy for brain tumors: current pitfalls and emerging strategies to overcome therapeutic resistance SK Totsch, C Schlappi, KD Kang, AS Ishizuka, GM Lynn, B Fox, ... Oncogene 38 (34), 6159-6171, 2019 | 56 | 2019 |
Impact of polymer-TLR-7/8 agonist (adjuvant) morphology on the potency and mechanism of CD8 T cell induction GM Lynn, P Chytil, JR Francica, A Lagová, G Kueberuwa, AS Ishizuka, ... Biomacromolecules 20 (2), 854-870, 2019 | 45 | 2019 |
Star nanoparticles delivering HIV-1 peptide minimal immunogens elicit near-native envelope antibody responses in nonhuman primates JR Francica, R Laga, GM Lynn, G Mužíková, L Androvič, B Aussedat, ... PLoS biology 17 (6), e3000328, 2019 | 39 | 2019 |
Induction of anti-cancer T cell immunity by in situ vaccination using systemically administered nanomedicines GM Lynn, R Laga, CM Jewell Cancer letters 459, 192-203, 2019 | 29 | 2019 |
Therapeutic cancer vaccines for pediatric malignancies: advances, challenges, and emerging technologies HE Olsen, GM Lynn, PA Valdes, CD Cerecedo Lopez, AS Ishizuka, ... Neuro-Oncology Advances 3 (1), vdab027, 2021 | 17 | 2021 |
Cyclotriphosphazene-based star copolymers as structurally tunable nanocarriers with programmable biodegradability L Androvic, L Woldrichova, K Jozefjaková, M Pechar, GM Lynn, ... Macromolecules 54 (7), 3139-3157, 2021 | 12 | 2021 |
Antigenic competition affects the magnitude and breadth of CD8 T cell immunity following immunization with a nanoparticle neoantigen cancer vaccine NJ Blobel, A Ramirez-Valdez, AS Ishizuka, GM Lynn, RA Seder The Journal of Immunology 198 (1_Supplement), 73.20-73.20, 2017 | 5 | 2017 |
Intravenous heterologous prime-boost vaccination activates innate and adaptive immunity to promote tumor regression RA Ramirez-Valdez, F Baharom, A Khalilnezhad, SC Fussell, ... Cell reports 42 (6), 2023 | 4 | 2023 |
Expression vector delivery system and use thereof for inducing an immune response R Seder, G Lynn, L Seymour US Patent 10,799,580, 2020 | 4 | 2020 |
Fab-dimerized glycan-reactive antibodies neutralize HIV and are prevalent in humans and rhesus macaques WB Williams, RR Meyerhoff, RJ Edwards, H Li, NI Nicely, R Henderson, ... bioRxiv, 2020.06. 30.178921, 2020 | 3 | 2020 |