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Louise J. Barber
Louise J. Barber
Research Scientist, Institute of Cancer Research
Verified email at icr.ac.uk
Title
Cited by
Cited by
Year
RTEL1 maintains genomic stability by suppressing homologous recombination
LJ Barber, JL Youds, JD Ward, MJ McIlwraith, NJ O'Neil, MIR Petalcorin, ...
Cell 135 (2), 261-271, 2008
3912008
Secondary mutations in BRCA2 associated with clinical resistance to a PARP inhibitor
LJ Barber, S Sandhu, L Chen, J Campbell, I Kozarewa, K Fenwick, ...
The Journal of pathology 229 (3), 422-429, 2013
3182013
A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination
GY Zhao, E Sonoda, LJ Barber, H Oka, Y Murakawa, K Yamada, T Ikura, ...
Molecular cell 25 (5), 663-675, 2007
2622007
FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts
TBC London, LJ Barber, G Mosedale, GP Kelly, S Balasubramanian, ...
Journal of biological chemistry 283 (52), 36132-36139, 2008
2312008
Cancer evolution and the limits of predictability in precision cancer medicine
KA Lipinski, LJ Barber, MN Davies, M Ashenden, A Sottoriva, M Gerlinger
Trends in cancer 2 (1), 49-63, 2016
2292016
Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2
SA Martin, A McCarthy, LJ Barber, DJ Burgess, S Parry, CJ Lord, ...
EMBO molecular medicine 1 (6‐7), 323-337, 2009
1932009
Efficacy of chemotherapy in BRCA1/2 mutation carrier ovarian cancer in the setting of PARP inhibitor resistance: a multi-institutional study
JE Ang, C Gourley, CB Powell, H High, R Shapira-Frommer, ...
Clinical Cancer Research 19 (19), 5485-5493, 2013
1272013
HCLK2 is essential for the mammalian S-phase checkpoint and impacts on Chk1 stability
SJ Collis, LJ Barber, AJ Clark, JS Martin, JD Ward, SJ Boulton
Nature cell biology 9 (4), 391, 2007
1232007
Genomic and transcriptomic determinants of therapy resistance and immune landscape evolution during anti-EGFR treatment in colorectal cancer
A Woolston, K Khan, G Spain, LJ Barber, B Griffiths, R Gonzalez-Exposito, ...
Cancer cell 36 (1), 35-50. e9, 2019
1182019
Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells
Y Murakawa, E Sonoda, LJ Barber, W Zeng, K Yokomori, H Kimura, ...
Cancer research 67 (18), 8536-8543, 2007
1172007
DOG-1 is the Caenorhabditis elegans BRIP1/FANCJ homologue and functions in interstrand cross-link repair
JL Youds, LJ Barber, JD Ward, SJ Collis, NJ O'Neil, SJ Boulton, AM Rose
Molecular and cellular biology 28 (5), 1470-1479, 2008
1092008
Replication blocking lesions present a unique substrate for homologous recombination
JD Ward, LJ Barber, MIR Petalcorin, J Yanowitz, SJ Boulton
The EMBO journal 26 (14), 3384-3396, 2007
912007
Poly (ADP-ribose) polymerase (PARP) inhibitors for the treatment of advanced germline BRCA2 mutant prostate cancer
SK Sandhu, A Omlin, L Hylands, S Miranda, LJ Barber, R Riisnaes, ...
Annals of oncology 24 (5), 1416-1418, 2013
852013
DNA interstrand cross-link repair in the Saccharomyces cerevisiae cell cycle: overlapping roles for PSO2 (SNM1) with MutS factors and EXO1 during S phase
LJ Barber, TA Ward, JA Hartley, PJ McHugh
Molecular and cellular biology 25 (6), 2297-2309, 2005
802005
C. elegans FANCD2 responds to replication stress and functions in interstrand cross-link repair
SJ Collis, LJ Barber, JD Ward, JS Martin, SJ Boulton
DNA repair 5 (11), 1398-1406, 2006
762006
Human SNM1A suppresses the DNA repair defects of yeast pso2 mutants
A Hazrati, M Ramis-Castelltort, S Sarkar, LJ Barber, CJ Schofield, ...
DNA repair 7 (2), 230-238, 2008
692008
Dissecting cancer evolution at the macro-heterogeneity and micro-heterogeneity scale
LJ Barber, MN Davies, M Gerlinger
Current opinion in genetics & development 30, 1-6, 2015
672015
CEA expression heterogeneity and plasticity confer resistance to the CEA-targeting bispecific immunotherapy antibody cibisatamab (CEA-TCB) in patient-derived colorectal cancer …
R Gonzalez-Exposito, M Semiannikova, B Griffiths, K Khan, LJ Barber, ...
Journal for immunotherapy of cancer 7 (1), 101, 2019
522019
The MRT‐1 nuclease is required for DNA crosslink repair and telomerase activity in vivo in Caenorhabditis elegans
B Meier, LJ Barber, Y Liu, L Shtessel, SJ Boulton, A Gartner, S Ahmed
The EMBO journal 28 (22), 3549-3563, 2009
492009
Schizosaccharomyces pombe checkpoint response to DNA interstrand cross-links
S Lambert, SJ Mason, LJ Barber, JA Hartley, JA Pearce, AM Carr, ...
Molecular and cellular biology 23 (13), 4728-4737, 2003
462003
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