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Worldwide emergence of resistance to antifungal drugs challenges human health and food security
MC Fisher, NJ Hawkins, D Sanglard, SJ Gurr
Science 360 (6390), 739-742, 2018
Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences
D Sanglard, FC Odds
The Lancet infectious diseases 2 (2), 73-85, 2002
Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters
D Sanglard, K Kuchler, F Ischer, JL Pagani, M Monod, J Bille
Antimicrobial agents and chemotherapy 39 (11), 2378-2386, 1995
Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene
D Sanglard, F Ischer, M Monod, J Bille
Microbiology 143 (2), 405-416, 1997
Prevalence of Molecular Mechanisms of Resistance to Azole Antifungal Agents in Candida albicans Strains Displaying High-Level Fluconazole Resistance Isolated …
S Perea, JL López-Ribot, WR Kirkpatrick, RK McAtee, RA Santillán, ...
Antimicrobial agents and chemotherapy 45 (10), 2676-2684, 2001
Amino Acid Substitutions in the Cytochrome P-450 Lanosterol 14α-Demethylase (CYP51A1) from Azole-Resistant Candida albicans Clinical Isolates Contribute to …
D Sanglard, F Ischer, L Koymans, J Bille
Antimicrobial agents and chemotherapy 42 (2), 241-253, 1998
Mechanisms of antifungal drug resistance
LE Cowen, D Sanglard, SJ Howard, PD Rogers, DS Perlin
Cold Spring Harbor perspectives in medicine 5 (7), 2015
Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors
D Sanglard, F Ischer, M Monod, J Bille
Antimicrobial agents and chemotherapy 40 (10), 2300-2305, 1996
Emerging threats in antifungal-resistant fungal pathogens
D Sanglard
Frontiers in medicine 3, 11, 2016
A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans
A Coste, V Turner, F Ischer, J Morschhäuser, A Forche, A Selmecki, ...
Genetics 172 (4), 2139-2156, 2006
TAC1, Transcriptional Activator of CDR Genes, Is a New Transcription Factor Involved in the Regulation of Candida albicans ABC Transporters CDR1 and CDR2
AT Coste, M Karababa, F Ischer, J Bille, D Sanglard
Eukaryotic cell 3 (6), 1639-1652, 2004
Candida albicans Mutations in the Ergosterol Biosynthetic Pathway and Resistance to Several Antifungal Agents
D Sanglard, F Ischer, T Parkinson, D Falconer, J Bille
Antimicrobial agents and chemotherapy 47 (8), 2404-2412, 2003
The ATP Binding Cassette Transporter GeneCgCDR1 from Candida glabrata Is Involved in the Resistance of Clinical Isolates to Azole Antifungal Agents
D Sanglard, F Ischer, D Calabrese, PA Majcherczyk, J Bille
Antimicrobial agents and chemotherapy 43 (11), 2753-2765, 1999
Antifungal drug resistance in pathogenic fungi.
F Dromer, I Improvisi, M Lozano-Chiu, JH Rex, D Sanglard
Medical mycology 36, 119-128, 1998
A Human-Curated Annotation of the Candida albicans Genome
BR Braun, M van Het Hoog, C d'Enfert, M Martchenko, J Dungan, A Kuo, ...
PLoS genetics 1 (1), e1, 2005
Calcineurin A of Candida albicans: involvement in antifungal tolerance, cell morphogenesis and virulence
D Sanglard, F Ischer, O Marchetti, J Entenza, J Bille
Molecular microbiology 48 (4), 959-976, 2003
Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence
B Hube, D Sanglard, FC Odds, D Hess, M Monod, W Schäfer, AJ Brown, ...
Infection and immunity 65 (9), 3529-3538, 1997
Oxidation of benzo (a) pyrene by extracellular ligninases of Phanerochaete chrysosporium. Veratryl alcohol and stability of ligninase.
SD Haemmerli, MS Leisola, D Sanglard, A Fiechter
Journal of Biological Chemistry 261 (15), 6900-6903, 1986
A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence
D Sanglard, B Hube, M Monod, FC Odds, NA Gow
Infection and immunity 65 (9), 3539-3546, 1997
Genotypic Evolution of Azole Resistance Mechanisms in Sequential Candida albicans Isolates
A Coste, A Selmecki, A Forche, D Diogo, ME Bougnoux, C d'Enfert, ...
Eukaryotic cell 6 (10), 1889-1904, 2007
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