Sanglard
Sanglard
University of Lausanne and University Hospital Center
Verified email at chuv.ch - Homepage
TitleCited byYear
Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences
D Sanglard, FC Odds
The Lancet infectious diseases 2 (2), 73-85, 2002
9112002
Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters.
D Sanglard, K Kuchler, F Ischer, JL Pagani, M Monod, J Bille
Antimicrobial agents and chemotherapy 39 (11), 2378-2386, 1995
8941995
Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene
D Sanglard, F Ischer, M Monod, J Bille
Microbiology 143 (2), 405-416, 1997
6231997
Amino acid substitutions in the cytochrome P-450 lanosterol 14α-demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole …
D Sanglard, F Ischer, L Koymans, J Bille
Antimicrobial agents and chemotherapy 42 (2), 241-253, 1998
5191998
Prevalence of molecular mechanisms of resistance to azole antifungal agents in Candida albicans strains displaying high-level fluconazole resistance isolated from human …
S Perea, JL López-Ribot, WR Kirkpatrick, RK McAtee, RA Santillán, ...
Antimicrobial agents and chemotherapy 45 (10), 2676-2684, 2001
5122001
Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors.
D Sanglard, F Ischer, M Monod, J Bille
Antimicrobial agents and chemotherapy 40 (10), 2300-2305, 1996
4131996
Antifungal drug resistance in pathogenic fungi.
HB Vanden, F Dromer, I Improvisi, M Lozano-Chiu, JH Rex, D Sanglard
Medical mycology 36, 119-128, 1998
3661998
The ATP binding cassette transporter GeneCgCDR1 from Candida glabrata is involved in the resistance of clinical isolates to azole antifungal agents
D Sanglard, F Ischer, D Calabrese, PA Majcherczyk, J Bille
Antimicrobial agents and chemotherapy 43 (11), 2753-2765, 1999
3561999
A human-curated annotation of the Candida albicans genome
BR Braun, M Van het Hoog, C d'Enfert, M Martchenko, J Dungan, A Kuo, ...
PLoS genetics 1 (1), e1, 2005
3522005
A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans
A Coste, V Turner, F Ischer, J Morschhäuser, A Forche, A Selmecki, ...
Genetics 172 (4), 2139-2156, 2006
3322006
TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2
AT Coste, M Karababa, F Ischer, J Bille, D Sanglard
Eukaryotic cell 3 (6), 1639-1652, 2004
3322004
Calcineurin A of Candida albicans: involvement in antifungal tolerance, cell morphogenesis and virulence
D Sanglard, F Ischer, O Marchetti, J Entenza, J Bille
Molecular microbiology 48 (4), 959-976, 2003
3302003
Oxidation of benzo (a) pyrene by extracellular ligninases of Phanerochaete chrysosporium. Veratryl alcohol and stability of ligninase.
SD Haemmerli, MS Leisola, D Sanglard, A Fiechter
Journal of Biological Chemistry 261 (15), 6900-6903, 1986
3221986
A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence.
D Sanglard, B Hube, M Monod, FC Odds, NA Gow
Infection and immunity 65 (9), 3539-3546, 1997
3151997
Candida albicans mutations in the ergosterol biosynthetic pathway and resistance to several antifungal agents
D Sanglard, F Ischer, T Parkinson, D Falconer, J Bille
Antimicrobial Agents and Chemotherapy 47 (8), 2404-2412, 2003
3082003
Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence.
B Hube, D Sanglard, FC Odds, D Hess, M Monod, W Schäfer, AJ Brown, ...
Infection and immunity 65 (9), 3529-3538, 1997
3041997
Candida albicans hyphal formation and the expression of the Efg1-regulated proteinases Sap4 to Sap6 are required for the invasion of parenchymal organs
A Felk, M Kretschmar, A Albrecht, M Schaller, S Beinhauer, T Nichterlein, ...
Infection and immunity 70 (7), 3689-3700, 2002
2782002
Multiplicity of genes encoding secreted aspartic proteinases in Candida species
M Monod, G Togni, B Hube, D Sanglard
Molecular microbiology 13 (2), 357-368, 1994
2781994
Genotypic evolution of azole resistance mechanisms in sequential Candida albicans isolates
A Coste, A Selmecki, A Forche, D Diogo, ME Bougnoux, C d'Enfert, ...
Eukaryotic cell 6 (10), 1889-1904, 2007
2712007
Potent synergism of the combination of fluconazole and cyclosporine in Candida albicans
O Marchetti, P Moreillon, MP Glauser, J Bille, D Sanglard
Antimicrobial agents and chemotherapy 44 (9), 2373-2381, 2000
2612000
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