In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector L Naldini, U Blömer, P Gallay, D Ory, R Mulligan, FH Gage, IM Verma, ... Science 272 (5259), 263-267, 1996 | 6606 | 1996 |
A third-generation lentivirus vector with a conditional packaging system T Dull, R Zufferey, M Kelly, RJ Mandel, M Nguyen, D Trono, L Naldini Journal of virology 72 (11), 8463-8471, 1998 | 3982 | 1998 |
Gene therapy-promises, problems and prospects IM Verma, N Somia Nature 389 (6648), 239-242, 1997 | 2978 | 1997 |
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo R Zufferey, D Nagy, RJ Mandel, L Naldini, D Trono Nature biotechnology 15 (9), 871-875, 1997 | 2541 | 1997 |
Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery R Zufferey, T Dull, RJ Mandel, A Bukovsky, D Quiroz, L Naldini, D Trono Journal of virology 72 (12), 9873-9880, 1998 | 2478 | 1998 |
Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. L Naldini, U Blömer, FH Gage, D Trono, IM Verma Proceedings of the National Academy of Sciences 93 (21), 11382-11388, 1996 | 2144 | 1996 |
Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics MA Kay, JC Glorioso, L Naldini Nature medicine 7 (1), 33-40, 2001 | 1879 | 2001 |
Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth. F Bussolino, MF Di Renzo, M Ziche, E Bocchietto, M Olivero, L Naldini, ... The Journal of cell biology 119 (3), 629-641, 1992 | 1657 | 1992 |
Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences A Follenzi, LE Ailles, S Bakovic, M Geuna, L Naldini Nature genetics 25 (2), 217-222, 2000 | 1599 | 2000 |
Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors M De Palma, MA Venneri, R Galli, LS Sergi, LS Politi, M Sampaolesi, ... Cancer cell 8 (3), 211-226, 2005 | 1535 | 2005 |
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy A Biffi, E Montini, L Lorioli, M Cesani, F Fumagalli, T Plati, C Baldoli, ... Science 341 (6148), 1233158, 2013 | 1386 | 2013 |
Gene therapy returns to centre stage L Naldini Nature 526 (7573), 351-360, 2015 | 1340 | 2015 |
Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome A Aiuti, L Biasco, S Scaramuzza, F Ferrua, MP Cicalese, C Baricordi, ... Science 341 (6148), 1233151, 2013 | 1250 | 2013 |
Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery A Lombardo, P Genovese, CM Beausejour, S Colleoni, YL Lee, KA Kim, ... Nature biotechnology 25 (11), 1298-1306, 2007 | 1171 | 2007 |
Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector U Blömer, L Naldini, T Kafri, D Trono, IM Verma, FH Gage Journal of virology 71 (9), 6641-6649, 1997 | 1005 | 1997 |
Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-MET. L Naldini, E Vigna, RP Narsimhan, G Gaudino, R Zarnegar, ... Oncogene 6 (4), 501-504, 1991 | 953 | 1991 |
Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration E Montini, D Cesana, M Schmidt, F Sanvito, M Ponzoni, C Bartholomae, ... Nature biotechnology 24 (6), 687-696, 2006 | 889 | 2006 |
Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor. L Naldini, KM Weidner, E Vigna, G Gaudino, A Bardelli, C Ponzetto, ... The EMBO journal 10 (10), 2867-2878, 1991 | 832 | 1991 |
Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells R Mazzieri, F Pucci, D Moi, E Zonari, A Ranghetti, A Berti, LS Politi, ... Cancer cell 19 (4), 512-526, 2011 | 738 | 2011 |
An unbiased genome-wide analysis of zinc-finger nuclease specificity R Gabriel, A Lombardo, A Arens, JC Miller, P Genovese, C Kaeppel, ... Nature biotechnology 29 (9), 816-823, 2011 | 735 | 2011 |