Giorgio Trinchieri
Giorgio Trinchieri
Director, Cancer and Inflammation Program, Center for Cancer Research, NCI, NIH
Verified email at - Homepage
TitleCited byYear
Interleukin-12 and the regulation of innate resistance and adaptive immunity
G Trinchieri
Nature Reviews Immunology 3 (2), 133, 2003
Biology of natural killer cells
G Trinchieri
Advances in immunology 47, 187-376, 1989
Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
G Trinchieri
Annual review of immunology 13 (1), 251-276, 1995
Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes.
M Kobayashi, L Fitz, M Ryan, RM Hewick, SC Clark, S Chan, R Loudon, ...
Journal of Experimental Medicine 170 (3), 827-845, 1989
Plasmacytoid dendritic cells in immunity
M Colonna, G Trinchieri, YJ Liu
Nature immunology 5 (12), 1219, 2004
Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells.
R Manetti, P Parronchi, MG Giudizi, MP Piccinni, E Maggi, G Trinchieri, ...
Journal of Experimental Medicine 177 (4), 1199-1204, 1993
Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.
SE Macatonia, NA Hosken, M Litton, P Vieira, CS Hsieh, JA Culpepper, ...
The Journal of Immunology 154 (10), 5071-5079, 1995
Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells.
A D'andrea, M Aste-Amezaga, NM Valiante, X Ma, M Kubin, G Trinchieri
Journal of Experimental Medicine 178 (3), 1041-1048, 1993
Cooperation of Toll-like receptor signals in innate immune defence
G Trinchieri, A Sher
Nature Reviews Immunology 7 (3), 179, 2007
Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells.
A D'Andrea, M Rengaraju, NM Valiante, J Chehimi, M Kubin, M Aste, ...
Journal of Experimental Medicine 176 (5), 1387-1398, 1992
Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes
G Trinchieri
Blood 84 (12), 4008-4027, 1994
Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology
C Asselin-Paturel, A Boonstra, M Dalod, I Durand, N Yessaad, ...
Nature immunology 2 (12), 1144, 2001
Reciprocal activating interaction between natural killer cells and dendritic cells
F Gerosa, B Baldani-Guerra, C Nisii, V Marchesini, G Carra, G Trinchieri
Journal of Experimental Medicine 195 (3), 327-333, 2002
Interleukin-12 and its role in the generation of TH1 cells
G Trinchieri
Immunology today 14 (7), 335-338, 1993
Anti-viral activity induced by culturing lymphocytes with tumor-derived or virus-transformed cells. Enhancement of human natural killer cell activity by interferon and …
G Trinchieri, D Santoli
Journal of Experimental Medicine 147 (5), 1314-1333, 1978
The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses
G Trinchieri, S Pflanz, RA Kastelein
Immunity 19 (5), 641-644, 2003
Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers.
SH Chan, B Perussia, JW Gupta, M Kobayashi, M Pospisil, HA Young, ...
Journal of Experimental Medicine 173 (4), 869-879, 1991
In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction …
RT Gazzinelli, M Wysocka, S Hieny, T Scharton-Kersten, A Cheever, ...
The Journal of Immunology 157 (2), 798-805, 1996
Interleukin-12: a cytokine at the interface of inflammation and immunity
G Trinchieri
Advances in immunology 70, 83-243, 1998
The adjuvant effect of interleukin-12 in a vaccine against Leishmania major
LC Afonso, TM Scharton, LQ Vieira, M Wysocka, G Trinchieri, P Scott
Science 263 (5144), 235-237, 1994
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