| Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis SR Nielsen, V Quaranta, A Linford, P Emeagi, C Rainer, A Santos, ... Nature cell biology 18 (5), 549-560, 2016 | 414 | 2016 |
| An integrin β3–KRAS–RalB complex drives tumour stemness and resistance to EGFR inhibition L Seguin, S Kato, A Franovic, MF Camargo, J Lesperance, KC Elliott, ... Nature cell biology 16 (5), 457-468, 2014 | 396 | 2014 |
| Chemoresistance in pancreatic cancer is driven by stroma-derived insulin-like growth factors L Ireland, A Santos, MS Ahmed, C Rainer, SR Nielsen, V Quaranta, ... Cancer research 76 (23), 6851-6863, 2016 | 253 | 2016 |
| PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments I Tanjoni, C Walsh, S Uryu, A Tomar, JO Nam, A Mielgo, ST Lim, C Liang, ... Cancer biology & therapy 9 (10), 764-777, 2010 | 175 | 2010 |
| Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis S Barbero, A Mielgo, V Torres, T Teitz, DJ Shields, D Mikolon, M Bogyo, ... Cancer research 69 (9), 3755-3763, 2009 | 165 | 2009 |
| The marine lipopeptide somocystinamide A triggers apoptosis via caspase 8 W Wrasidlo, A Mielgo, VA Torres, S Barbero, K Stoletov, TL Suyama, ... Proceedings of the National Academy of Sciences 105 (7), 2313-2318, 2008 | 141 | 2008 |
| Macrophage-derived granulin drives resistance to immune checkpoint inhibition in metastatic pancreatic cancer V Quaranta, C Rainer, SR Nielsen, ML Raymant, MS Ahmed, DD Engle, ... Cancer research 78 (15), 4253-4269, 2018 | 129 | 2018 |
| Impact of tumour associated macrophages in pancreatic cancer A Mielgo, MC Schmid BMB reports 46 (3), 131, 2013 | 128 | 2013 |
| Blockade of MIF–CD74 signalling on macrophages and dendritic cells restores the antitumour immune response against metastatic melanoma CR Figueiredo, RA Azevedo, S Mousdell, PT Resende-Lara, L Ireland, ... Frontiers in immunology 9, 1132, 2018 | 121 | 2018 |
| Distinct FAK-Src activation events promote α5β1 and α4β1 integrin-stimulated neuroblastoma cell motility L Wu, JA Bernard-Trifilo, Y Lim, ST Lim, SK Mitra, S Uryu, M Chen, ... Oncogene 27 (10), 1439-1448, 2008 | 117 | 2008 |
| Apoptosis and pathogenesis of melanoma and nonmelanoma skin cancer P Erb, J Ji, E Kump, A Mielgo, M Wernli Sunlight, Vitamin D and Skin Cancer, 283-295, 2008 | 103 | 2008 |
| Identification of a critical tyrosine residue in caspase 8 that promotes cell migration S Barbero, D Barila, A Mielgo, V Stagni, K Clair, D Stupack Journal of biological chemistry 283 (19), 13031-13034, 2008 | 102 | 2008 |
| Macrophages and fibroblasts, key players in cancer chemoresistance LV Ireland, A Mielgo Frontiers in cell and developmental biology 6, 131, 2018 | 101 | 2018 |
| Rab5 mediates caspase-8–promoted cell motility and metastasis VA Torres, A Mielgo, S Barbero, R Hsiao, JA Wilkins, DG Stupack Molecular biology of the cell 21 (2), 369-376, 2010 | 98 | 2010 |
| A novel antiapoptotic mechanism based on interference of Fas signaling by CD44 variant isoforms A Mielgo, M van Driel, A Bloem, L Landmann, U Günthert Cell Death & Differentiation 13 (3), 465-477, 2006 | 91 | 2006 |
| Oncogenic Ras/Src cooperativity in pancreatic neoplasia DJ Shields, EA Murphy, JS Desgrosellier, A Mielgo, SKM Lau, LA Barnes, ... Oncogene 30 (18), 2123-2134, 2011 | 82 | 2011 |
| RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia DJ Shields, S Niessen, EA Murphy, A Mielgo, JS Desgrosellier, SKM Lau, ... Proceedings of the National Academy of Sciences 107 (5), 2189-2194, 2010 | 77 | 2010 |
| A MEK-independent role for CRAF in mitosis and tumor progression A Mielgo, L Seguin, M Huang, MF Camargo, S Anand, A Franovic, ... Nature medicine 17 (12), 1641-1645, 2011 | 70 | 2011 |
| Blockade of insulin-like growth factors increases efficacy of paclitaxel in metastatic breast cancer L Ireland, A Santos, F Campbell, C Figueiredo, D Hammond, LG Ellies, ... Oncogene 37 (15), 2022-2036, 2018 | 68 | 2018 |
| Paclitaxel promotes a caspase 8-mediated apoptosis through death effector domain association with microtubules A Mielgo, VA Torres, K Clair, S Barbero, DG Stupack Oncogene 28 (40), 3551-3562, 2009 | 67 | 2009 |
