Benjamin P Fairfax
Benjamin P Fairfax
Wellcome Intermediate Clinical Fellow, MRC Weatherall Institute for Molecular Medicine, Oxford
Verified email at oncology.ox.ac.uk - Homepage
Title
Cited by
Cited by
Year
Systematic identification of trans eQTLs as putative drivers of known disease associations
HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ...
Nature genetics 45 (10), 1238-1243, 2013
14842013
Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression
BP Fairfax, P Humburg, S Makino, V Naranbhai, D Wong, E Lau, L Jostins, ...
Science 343 (6175), 2014
6052014
Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles
BP Fairfax, S Makino, J Radhakrishnan, K Plant, S Leslie, A Dilthey, ...
Nature genetics 44 (5), 502-510, 2012
4792012
Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus
J Bentham, DL Morris, DSC Graham, CL Pinder, P Tombleson, ...
Nature genetics 47 (12), 1457-1464, 2015
4352015
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis
U Vősa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
BioRxiv, 447367, 2018
2352018
Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization
K Břnnelykke, MC Matheson, TH Pers, R Granell, DP Strachan, AC Alves, ...
Nature genetics 45 (8), 902-906, 2013
2282013
Phospho-dependent functional modulation of GABAB receptors by the metabolic sensor AMP-dependent protein kinase
N Kuramoto, ME Wilkins, BP Fairfax, R Revilla-Sanchez, M Terunuma, ...
Neuron 53 (2), 233-247, 2007
2002007
A common haplotype lowers PU. 1 expression in myeloid cells and delays onset of Alzheimer's disease
K Huang, E Marcora, AA Pimenova, AF Di Narzo, M Kapoor, SC Jin, ...
Nature neuroscience 20 (8), 1052, 2017
1942017
Leprosy and the adaptation of human toll-like receptor 1
SH Wong, S Gochhait, D Malhotra, FH Pettersson, YY Teo, CC Khor, ...
PLoS Pathog 6 (7), e1000979, 2010
1532010
Phosphorylation and chronic agonist treatment atypically modulate GABAB receptor cell surface stability
BP Fairfax, JA Pitcher, MGH Scott, AR Calver, MN Pangalos, SJ Moss, ...
Journal of Biological Chemistry 279 (13), 12565-12573, 2004
1172004
Genomic modulators of gene expression in human neutrophils
V Naranbhai, BP Fairfax, S Makino, P Humburg, D Wong, E Ng, AVS Hill, ...
Nature communications 6 (1), 1-13, 2015
1162015
Cell specific eQTL analysis without sorting cells
HJ Westra, D Arends, T Esko, MJ Peters, C Schurmann, K Schramm, ...
PLoS genetics 11 (5), e1005223, 2015
942015
Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals
Y Guo, MB Lanktree, KC Taylor, H Hakonarson, LA Lange, BJ Keating, ...
Human molecular genetics 22 (1), 184-201, 2013
832013
Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis
MH Al-Mossawi, L Chen, H Fang, A Ridley, J De Wit, N Yager, ...
Nature communications 8 (1), 1-11, 2017
742017
Pervasive haplotypic variation in the spliceo-transcriptome of the human major histocompatibility complex
C Vandiedonck, MS Taylor, HE Lockstone, K Plant, JM Taylor, C Durrant, ...
Genome research 21 (7), 1042-1054, 2011
722011
Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells
S Kasela, K Kisand, L Tserel, E Kaleviste, A Remm, K Fischer, T Esko, ...
PLoS genetics 13 (3), e1006643, 2017
692017
Unravelling the unusual signalling properties of the GABAB receptor
A Couve, AR Calver, B Fairfax, SJ Moss, MN Pangalos
Biochemical pharmacology 68 (8), 1527-1536, 2004
672004
Genetics of gene expression in immunity to infection
BP Fairfax, JC Knight
Current opinion in immunology 30, 63-71, 2014
592014
Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma
BP Fairfax, CA Taylor, RA Watson, I Nassiri, S Danielli, H Fang, EA Mahé, ...
Nature medicine 26 (2), 193-199, 2020
552020
A genetics-led approach defines the drug target landscape of 30 immune-related traits
H Fang, H De Wolf, B Knezevic, KL Burnham, J Osgood, A Sanniti, ...
Nature genetics 51 (7), 1082-1091, 2019
542019
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