Benjamin P Fairfax
Benjamin P Fairfax
Professor of Cancer Immunogenetics, Department of Oncology, MRC WIMM, University of Oxford
Verified email at - Homepage
Cited by
Cited by
Systematic identification of trans eQTLs as putative drivers of known disease associations
HJ Westra, MJ Peters, T Esko, H Yaghootkar, C Schurmann, J Kettunen, ...
Nature genetics 45 (10), 1238-1243, 2013
Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus
J Bentham, DL Morris, DS Cunninghame Graham, CL Pinder, ...
Nature genetics 47 (12), 1457-1464, 2015
Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression
BP Fairfax, P Humburg, S Makino, V Naranbhai, D Wong, E Lau, L Jostins, ...
Science 343 (6175), 1246949, 2014
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
U Vősa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
Nature genetics 53 (9), 1300-1310, 2021
Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles
BP Fairfax, S Makino, J Radhakrishnan, K Plant, S Leslie, A Dilthey, ...
Nature genetics 44 (5), 502-510, 2012
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis
U Vősa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ...
BioRxiv, 447367, 2018
A common haplotype lowers PU. 1 expression in myeloid cells and delays onset of Alzheimer's disease
K Huang, E Marcora, AA Pimenova, AF Di Narzo, M Kapoor, SC Jin, ...
Nature neuroscience 20 (8), 1052-1061, 2017
Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization
K Břnnelykke, MC Matheson, TH Pers, R Granell, DP Strachan, AC Alves, ...
Nature genetics 45 (8), 902-906, 2013
Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma
BP Fairfax, CA Taylor, RA Watson, I Nassiri, S Danielli, H Fang, EA Mahé, ...
Nature medicine 26 (2), 193-199, 2020
Phospho-dependent functional modulation of GABAB receptors by the metabolic sensor AMP-dependent protein kinase
N Kuramoto, ME Wilkins, BP Fairfax, R Revilla-Sanchez, M Terunuma, ...
Neuron 53 (2), 233-247, 2007
Leprosy and the adaptation of human toll-like receptor 1
SH Wong, S Gochhait, D Malhotra, FH Pettersson, YY Teo, CC Khor, ...
PLoS pathogens 6 (7), e1000979, 2010
A genetics-led approach defines the drug target landscape of 30 immune-related traits
H Fang, H De Wolf, B Knezevic, KL Burnham, J Osgood, A Sanniti, ...
Nature genetics 51 (7), 1082-1091, 2019
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
DJ Ahern, Z Ai, M Ainsworth, C Allan, A Allcock, B Angus, MA Ansari, ...
Cell 185 (5), 916-938. e58, 2022
Genomic modulators of gene expression in human neutrophils
V Naranbhai, BP Fairfax, S Makino, P Humburg, D Wong, E Ng, AVS Hill, ...
Nature communications 6 (1), 7545, 2015
An immunodominant NP105–113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease
Y Peng, SL Felce, D Dong, F Penkava, AJ Mentzer, X Yao, G Liu, Z Yin, ...
Nature immunology 23 (1), 50-61, 2022
Cell specific eQTL analysis without sorting cells
HJ Westra, D Arends, T Esko, MJ Peters, C Schurmann, K Schramm, ...
PLoS genetics 11 (5), e1005223, 2015
Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis
MH Al-Mossawi, L Chen, H Fang, A Ridley, J De Wit, N Yager, ...
Nature communications 8 (1), 1510, 2017
Phosphorylation and chronic agonist treatment atypically modulate GABAB receptor cell surface stability
BP Fairfax, JA Pitcher, MGH Scott, AR Calver, MN Pangalos, SJ Moss, ...
Journal of Biological Chemistry 279 (13), 12565-12573, 2004
Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells
S Kasela, K Kisand, L Tserel, E Kaleviste, A Remm, K Fischer, T Esko, ...
PLoS genetics 13 (3), e1006643, 2017
Interferon-gamma–producing CD8+ tissue resident memory T cells are a targetable hallmark of immune checkpoint inhibitor–colitis
SC Sasson, SM Slevin, VTF Cheung, I Nassiri, A Olsson-Brown, E Fryer, ...
Gastroenterology 161 (4), 1229-1244. e9, 2021
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