| Two routes to leukemic transformation after a JAK2 mutation–positive myeloproliferative neoplasm PA Beer, F Delhommeau, JP LeCouédic, MA Dawson, E Chen, ... Blood, The Journal of the American Society of Hematology 115 (14), 2891-2900, 2010 | 328 | 2010 |
| Mutant calreticulin requires both its mutant C-terminus and the thrombopoietin receptor for oncogenic transformation S Elf, NS Abdelfattah, E Chen, J Perales-Patón, EA Rosen, A Ko, ... Cancer discovery 6 (4), 368-381, 2016 | 266 | 2016 |
| JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F–positive essential thrombocythemia J Li, D Spensberger, JS Ahn, S Anand, PA Beer, C Ghevaert, E Chen, ... Blood, The Journal of the American Society of Hematology 116 (9), 1528-1538, 2010 | 239 | 2010 |
| Rps14 haploinsufficiency causes a block in erythroid differentiation mediated by S100A8 and S100A9 RK Schneider, M Schenone, MV Ferreira, R Kramann, CE Joyce, ... Nature medicine 22 (3), 288-297, 2016 | 234 | 2016 |
| Distinct clinical phenotypes associated with JAK2V617F reflect differential STAT1 signaling E Chen, PA Beer, AL Godfrey, CA Ortmann, J Li, AP Costa-Pereira, ... Cancer cell 18 (5), 524-535, 2010 | 209 | 2010 |
| Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms W Tapper, AV Jones, R Kralovics, AS Harutyunyan, K Zoi, W Leung, ... Nature communications 6 (1), 6691, 2015 | 185 | 2015 |
| Janus Kinase Deregulation in Leukemia and Lymphoma E Chen, LM Staudt, AR Green Immunity 36 (4), 529-541, 2012 | 159 | 2012 |
| The transcription factor encyclopedia D Yusuf, SL Butland, MI Swanson, E Bolotin, A Ticoll, WA Cheung, ... Genome biology 13, 1-25, 2012 | 129 | 2012 |
| JAK2V617F homozygosity arises commonly and recurrently in PV and ET, but PV is characterized by expansion of a dominant homozygous subclone AL Godfrey, E Chen, F Pagano, CA Ortmann, Y Silber, B Bellosillo, ... Blood, The Journal of the American Society of Hematology 120 (13), 2704-2707, 2012 | 126 | 2012 |
| Discovering language model behaviors with model-written evaluations E Perez, S Ringer, K Lukošiūtė, K Nguyen, E Chen, S Heiner, C Pettit, ... arXiv preprint arXiv:2212.09251, 2022 | 124 | 2022 |
| Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms E Chen, RK Schneider, LJ Breyfogle, EA Rosen, L Poveromo, S Elf, A Ko, ... Blood, The Journal of the American Society of Hematology 125 (2), 327-335, 2015 | 123 | 2015 |
| Mouse models of myeloproliferative neoplasms: JAK of all grades J Li, DG Kent, E Chen, AR Green Disease models & mechanisms 4 (3), 311-317, 2011 | 123 | 2011 |
| Characterization of elongation factor-1A (eEF1A-1) and eEF1A-2/S1 protein expression in normal and wasted mice A Khalyfa, D Bourbeau, E Chen, E Petroulakis, J Pan, S Xu, E Wang Journal of Biological Chemistry 276 (25), 22915-22922, 2001 | 120 | 2001 |
| Rapid up-regulation of peptide elongation factor EF-1α protein levels is an immediate early event during oxidative stress-induced apoptosis E Chen, G Proestou, D Bourbeau, E Wang Experimental cell research 259 (1), 140-148, 2000 | 119 | 2000 |
| Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein E Chen, ND Salinas, Y Huang, F Ntumngia, MD Plasencia, ML Gross, ... Proceedings of the National Academy of Sciences 113 (22), 6277-6282, 2016 | 95 | 2016 |
| Defining the requirements for the pathogenic interaction between mutant calreticulin and MPL in MPN S Elf, NS Abdelfattah, AJ Baral, D Beeson, JF Rivera, A Ko, N Florescu, ... Blood, The Journal of the American Society of Hematology 131 (7), 782-786, 2018 | 88 | 2018 |
| JAK2V617F homozygosity drives a phenotypic switch in myeloproliferative neoplasms, but is insufficient to sustain disease J Li, DG Kent, AL Godfrey, H Manning, J Nangalia, A Aziz, E Chen, ... Blood, The Journal of the American Society of Hematology 123 (20), 3139-3151, 2014 | 87 | 2014 |
| How does JAK2V617F contribute to the pathogenesis of myeloproliferative neoplasms? E Chen, A Mullally Hematology 2014, the American Society of Hematology Education Program Book …, 2014 | 68 | 2014 |
| ID1 promotes expansion and survival of primary erythroid cells and is a target of JAK2V617F-STAT5 signaling AD Wood, E Chen, IJ Donaldson, S Hattangadi, KA Burke, MA Dawson, ... Blood, The Journal of the American Society of Hematology 114 (9), 1820-1830, 2009 | 61 | 2009 |
| Mechanism of completion of peptidyltransferase centre assembly in eukaryotes V Kargas, P Castro-Hartmann, N Escudero-Urquijo, K Dent, C Hilcenko, ... Elife 8, e44904, 2019 | 53 | 2019 |
