Citrullination regulates pluripotency and histone H1 binding to chromatin MA Christophorou, G Castelo-Branco, RP Halley-Stott, CS Oliveira, ... Nature 507 (7490), 104-108, 2014 | 433 | 2014 |
A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages A Radzisheuskaya, G Le Bin Chia, RL Dos Santos, TW Theunissen, ... Nature cell biology 15 (6), 579-590, 2013 | 233 | 2013 |
MBD3/NuRD facilitates induction of pluripotency in a context-dependent manner RL Dos Santos, L Tosti, A Radzisheuskaya, IM Caballero, K Kaji, ... Cell stem cell 15 (1), 102-110, 2014 | 206 | 2014 |
Optimizing sgRNA position markedly improves the efficiency of CRISPR/dCas9-mediated transcriptional repression A Radzisheuskaya, D Shlyueva, I Müller, K Helin Nucleic acids research 44 (18), e141-e141, 2016 | 155 | 2016 |
PRMT5 methylome profiling uncovers a direct link to splicing regulation in acute myeloid leukemia A Radzisheuskaya, PV Shliaha, V Grinev, E Lorenzini, S Kovalchuk, ... Nature structural & molecular biology 26 (11), 999-1012, 2019 | 140 | 2019 |
Do all roads lead to Oct4? The emerging concepts of induced pluripotency A Radzisheuskaya, JCR Silva Trends in cell biology 24 (5), 275-284, 2014 | 138 | 2014 |
Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency V Pasque, A Radzisheuskaya, A Gillich, RP Halley-Stott, M Panamarova, ... Journal of cell science 125 (24), 6094-6104, 2012 | 119 | 2012 |
Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self‐renewal and early development MT Pedersen, SM Kooistra, A Radzisheuskaya, A Laugesen, ... The EMBO journal 35 (14), 1550-1564, 2016 | 94 | 2016 |
Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain TW Theunissen, Y Costa, A Radzisheuskaya, AL van Oosten, F Lavial, ... Development 138 (22), 4853-4865, 2011 | 92 | 2011 |
NANOG amplifies STAT3 activation and they synergistically induce the naive pluripotent program HT Stuart, AL Van Oosten, A Radzisheuskaya, G Martello, A Miller, ... Current Biology 24 (3), 340-346, 2014 | 76 | 2014 |
Tcf15 primes pluripotent cells for differentiation OR Davies, CY Lin, A Radzisheuskaya, X Zhou, J Taube, G Blin, ... Cell reports 3 (2), 472-484, 2013 | 69 | 2013 |
Complex-dependent histone acetyltransferase activity of KAT8 determines its role in transcription and cellular homeostasis A Radzisheuskaya, PV Shliaha, VV Grinev, D Shlyueva, H Damhofer, ... Molecular cell 81 (8), 1749-1765. e8, 2021 | 61 | 2021 |
PRMT5 Inhibition Modulates E2F1 Methylation and Gene-Regulatory Networks Leading to Therapeutic Efficacy in JAK2V617F-Mutant MPN F Pastore, N Bhagwat, A Pastore, A Radzisheuskaya, A Karzai, ... Cancer discovery 10 (11), 1742-1757, 2020 | 61 | 2020 |
MPP8 is essential for sustaining self-renewal of ground-state pluripotent stem cells I Müller, AS Moroni, D Shlyueva, S Sahadevan, EM Schoof, ... Nature communications 12 (1), 3034, 2021 | 44 | 2021 |
A functional link between nuclear RNA decay and transcriptional control mediated by the polycomb repressive complex 2 W Garland, I Comet, M Wu, A Radzisheuskaya, L Rib, K Vitting-Seerup, ... Cell reports 29 (7), 1800-1811. e6, 2019 | 44 | 2019 |
Distinct molecular trajectories converge to induce naive pluripotency HT Stuart, GG Stirparo, T Lohoff, LE Bates, M Kinoshita, CY Lim, EJ Sousa, ... Cell Stem Cell 25 (3), 388-406. e8, 2019 | 40 | 2019 |
Sox2 modulation increases naïve pluripotency plasticity KC Tremble, GG Stirparo, LE Bates, K Maskalenka, HT Stuart, K Jones, ... Iscience 24 (3), 2021 | 15 | 2021 |
Generation of locus-specific degradable tag knock-ins in mouse and human cell lines H Damhofer, A Radzisheuskaya, K Helin STAR protocols 2 (2), 100575, 2021 | 7 | 2021 |
An alternative NURF complex sustains acute myeloid leukemia by regulating the accessibility of insulator regions A Radzisheuskaya, I Peña‐Rømer, E Lorenzini, R Koche, Y Zhan, ... The EMBO Journal 42 (24), e114221, 2023 | 4 | 2023 |
Structural and thermodynamic features of intergenic and intronic human primary microRNAs VVG DV Posrednik, TV Ramanouskaya, AA Radzisheuskaya, AA Khatkevich, A Yu ... Molecular Biology 45 (3), 508-516, 2011 | 2 | 2011 |