Filipe Cabreiro
Filipe Cabreiro
London Institute of Medical Sciences, Imperial College London
Verified email at - Homepage
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Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism
F Cabreiro, C Au, KY Leung, N Vergara-Irigaray, HM Cochemé, T Noori, ...
Cell 153 (1), 228-239, 2013
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
C Burnett, S Valentini, F Cabreiro, M Goss, M Somogyvári, MD Piper, ...
nature 477 (7365), 482-485, 2011
Repurposing metformin: an old drug with new tricks in its binding pockets
R Pryor, F Cabreiro
Biochemical Journal 471 (3), 307-322, 2015
Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix
HM Cochemé, C Quin, SJ McQuaker, F Cabreiro, A Logan, TA Prime, ...
Cell metabolism 13 (3), 340-350, 2011
Worms need microbes too: microbiota, health and aging in Caenorhabditis elegans
F Cabreiro, D Gems
EMBO molecular medicine 5 (9), 1300-1310, 2013
Host-Microbe Co-metabolism Dictates Cancer Drug Efficacy in C. elegans
TA Scott, LM Quintaneiro, P Norvaisas, PP Lui, MP Wilson, KY Leung, ...
Cell 169 (3), 442-456. e18, 2017
Increased life span from overexpression of superoxide dismutase in Caenorhabditis elegans is not caused by decreased oxidative damage
F Cabreiro, D Ackerman, R Doonan, C Araiz, P Back, D Papp, ...
Free Radical Biology and Medicine 51 (8), 1575-1582, 2011
Host-microbe-drug-nutrient screen identifies bacterial effectors of metformin therapy
R Pryor, P Norvaisas, G Marinos, L Best, LB Thingholm, LM Quintaneiro, ...
Cell 178 (6), 1299-1312. e29, 2019
Methionine sulfoxide reductases: relevance to aging and protection against oxidative stress
F Cabreiro, CR Picot, B Friguet, I Petropoulos
Annals of the New York Academy of Sciences 1067 (1), 37-44, 2006
Anthranilate Fluorescence Marks a Calcium-Propagated Necrotic Wave That Promotes Organismal Death in C. elegans
C Coburn, E Allman, P Mahanti, A Benedetto, F Cabreiro, Z Pincus, ...
PLoS biology 11 (7), e1001613, 2013
Overexpression of mitochondrial methionine sulfoxide reductase B2 protects leukemia cells from oxidative stress-induced cell death and protein damage
F Cabreiro, CR Picot, M Perichon, J Castel, B Friguet, I Petropoulos
Journal of Biological Chemistry 283 (24), 16673-16681, 2008
The microbiome and aging
B Bana, F Cabreiro
Annual review of genetics 53, 239-261, 2019
Manipulation of in vivo iron levels can alter resistance to oxidative stress without affecting ageing in the nematode C. elegans
S Valentini, F Cabreiro, D Ackerman, MM Alam, MBA Kunze, CWM Kay, ...
Mechanisms of ageing and development 133 (5), 282-290, 2012
Overexpression of methionine sulfoxide reductases A and B2 protects MOLT-4 cells against zinc-induced oxidative stress
F Cabreiro, CR Picot, M Perichon, B Friguet, I Petropoulos
Antioxidants & Redox Signaling 11 (2), 215-226, 2009
Run-on of germline apoptosis promotes gonad senescence in C. elegans
Y de la Guardia, AF Gilliat, J Hellberg, P Rennert, F Cabreiro, D Gems
Oncotarget 7 (26), 39082, 2016
Bioaccumulation of therapeutic drugs by human gut bacteria
M Klünemann, S Andrejev, S Blasche, A Mateus, P Phapale, ...
Nature 597 (7877), 533-538, 2021
Reduced oxygen tension results in reduced human T cell proliferation and increased intracellular oxidative damage and susceptibility to apoptosis upon activation
A Larbi, F Cabreiro, H Zelba, S Marthandan, E Combet, B Friguet, ...
Free Radical Biology and Medicine 48 (1), 26-34, 2010
Folate metabolite profiling of different cell types and embryos suggests variation in folate one-carbon metabolism, including developmental changes in human embryonic brain
KY Leung, SCP De Castro, F Cabreiro, P Gustavsson, AJ Copp, ...
Molecular and cellular biochemistry 378 (1), 229-236, 2013
Zinc supplementation in the elderly subjects: effect on oxidized protein degradation and repair systems in peripheral blood lymphocytes
F Cabreiro, M Perichon, J Jatje, M Malavolta, E Mocchegiani, B Friguet, ...
Experimental gerontology 43 (5), 483-487, 2008
The role of the microbiome in drug response
R Pryor, D Martinez-Martinez, L Quintaneiro, F Cabreiro
Annual Review of Pharmacology and Toxicology 60, 417-435, 2020
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