Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism F Cabreiro, C Au, KY Leung, N Vergara-Irigaray, HM Cochemé, T Noori, ... Cell 153 (1), 228-239, 2013 | 1018 | 2013 |
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila C Burnett, S Valentini, F Cabreiro, M Goss, M Somogyvári, MD Piper, ... nature 477 (7365), 482-485, 2011 | 764 | 2011 |
Repurposing metformin: an old drug with new tricks in its binding pockets R Pryor, F Cabreiro Biochemical Journal 471 (3), 307-322, 2015 | 384 | 2015 |
Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix HM Cochemé, C Quin, SJ McQuaker, F Cabreiro, A Logan, TA Prime, ... Cell metabolism 13 (3), 340-350, 2011 | 327 | 2011 |
Host-microbe co-metabolism dictates cancer drug efficacy in C. elegans TA Scott, LM Quintaneiro, P Norvaisas, PP Lui, MP Wilson, KY Leung, ... Cell 169 (3), 442-456. e18, 2017 | 249 | 2017 |
Bioaccumulation of therapeutic drugs by human gut bacteria M Klünemann, S Andrejev, S Blasche, A Mateus, P Phapale, ... Nature 597 (7877), 533-538, 2021 | 220 | 2021 |
Host-microbe-drug-nutrient screen identifies bacterial effectors of metformin therapy R Pryor, P Norvaisas, G Marinos, L Best, LB Thingholm, LM Quintaneiro, ... Cell 178 (6), 1299-1312. e29, 2019 | 217 | 2019 |
Worms need microbes too: microbiota, health and aging in Caenorhabditis elegans F Cabreiro, D Gems EMBO molecular medicine 5 (9), 1300-1310, 2013 | 216 | 2013 |
The microbiome and aging B Bana, F Cabreiro Annual review of genetics 53 (1), 239-261, 2019 | 175 | 2019 |
Increased life span from overexpression of superoxide dismutase in Caenorhabditis elegans is not caused by decreased oxidative damage F Cabreiro, D Ackerman, R Doonan, C Araiz, P Back, D Papp, ... Free Radical Biology and Medicine 51 (8), 1575-1582, 2011 | 175 | 2011 |
Anthranilate Fluorescence Marks a Calcium-Propagated Necrotic Wave That Promotes Organismal Death in C. elegans C Coburn, E Allman, P Mahanti, A Benedetto, F Cabreiro, Z Pincus, ... PLoS biology 11 (7), e1001613, 2013 | 155 | 2013 |
Methionine sulfoxide reductases: relevance to aging and protection against oxidative stress F Cabreiro, CR Picot, B Friguet, I Petropoulos Annals of the New York Academy of Sciences 1067 (1), 37-44, 2006 | 139 | 2006 |
Overexpression of mitochondrial methionine sulfoxide reductase B2 protects leukemia cells from oxidative stress-induced cell death and protein damage F Cabreiro, CR Picot, M Perichon, J Castel, B Friguet, I Petropoulos Journal of Biological Chemistry 283 (24), 16673-16681, 2008 | 109 | 2008 |
Increased fidelity of protein synthesis extends lifespan VE Martinez-Miguel, C Lujan, T Espie, D Martinez-Martinez, S Moore, ... Cell metabolism 33 (11), 2288-2300. e12, 2021 | 83 | 2021 |
Manipulation of in vivo iron levels can alter resistance to oxidative stress without affecting ageing in the nematode C. elegans S Valentini, F Cabreiro, D Ackerman, MM Alam, MBA Kunze, CWM Kay, ... Mechanisms of ageing and development 133 (5), 282-290, 2012 | 67 | 2012 |
ARDD 2020: from aging mechanisms to interventions GV Mkrtchyan, K Abdelmohsen, P Andreux, I Bagdonaite, N Barzilai, ... Aging (Albany NY) 12 (24), 24484, 2020 | 60 | 2020 |
Run-on of germline apoptosis promotes gonad senescence in C. elegans Y de la Guardia, AF Gilliat, J Hellberg, P Rennert, F Cabreiro, D Gems Oncotarget 7 (26), 39082, 2016 | 58 | 2016 |
Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila I Bjedov, HM Cochemé, A Foley, D Wieser, NS Woodling, JI Castillo-Quan, ... PLoS genetics 16 (11), e1009083, 2020 | 54 | 2020 |
The role of the microbiome in drug response R Pryor, D Martinez-Martinez, L Quintaneiro, F Cabreiro Annual review of pharmacology and toxicology 60 (1), 417-435, 2020 | 49 | 2020 |
Mechanical properties measured by atomic force microscopy define health biomarkers in ageing C. elegans CL Essmann, D Martinez-Martinez, R Pryor, KY Leung, KB Krishnan, ... Nature communications 11 (1), 1043, 2020 | 46 | 2020 |