Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic CancerPancreatic Cancer Organoids Parallel Patient Response H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ... Cancer discovery 8 (9), 1112-1129, 2018 | 495 | 2018 |
Immunogenic neoantigens derived from gene fusions stimulate T cell responses W Yang, KW Lee, RM Srivastava, F Kuo, C Krishna, D Chowell, ... Nature medicine 25 (5), 767-775, 2019 | 179 | 2019 |
Genetic determinants of cisplatin resistance in patients with advanced germ cell tumors A Bagrodia, BH Lee, W Lee, EK Cha, JP Sfakianos, G Iyer, EJ Pietzak, ... Journal of Clinical Oncology 34 (33), 4000, 2016 | 126 | 2016 |
Indel variant analysis of short-read sequencing data with Scalpel H Fang, EA Bergmann, K Arora, V Vacic, MC Zody, I Iossifov, JA O'Rawe, ... Nature protocols 11 (12), 2529-2548, 2016 | 84 | 2016 |
Distinct classes of complex structural variation uncovered across thousands of cancer genome graphs K Hadi, X Yao, JM Behr, A Deshpande, C Xanthopoulakis, H Tian, ... Cell 183 (1), 197-210. e32, 2020 | 75 | 2020 |
Genome-wide somatic variant calling using localized colored de Bruijn graphs G Narzisi, A Corvelo, K Arora, EA Bergmann, M Shah, R Musunuri, ... Communications biology 1 (1), 1-9, 2018 | 70 | 2018 |
Gene silencing in Tribolium castaneum as a tool for the targeted identification of candidate RNAi targets in crop pests E Knorr, E Fishilevich, L Tenbusch, MLF Frey, M Rangasamy, A Billion, ... Scientific reports 8 (1), 1-15, 2018 | 67 | 2018 |
PGBD5 promotes site-specific oncogenic mutations in human tumors AG Henssen, R Koche, J Zhuang, E Jiang, C Reed, A Eisenberg, E Still, ... Nature genetics 49 (7), 1005-1014, 2017 | 56 | 2017 |
Conpair: concordance and contamination estimator for matched tumor–normal pairs EA Bergmann, BJ Chen, K Arora, V Vacic, MC Zody Bioinformatics 32 (20), 3196-3198, 2016 | 49 | 2016 |
Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia NA McNeer, J Philip, H Geiger, RE Ries, VP Lavallee, M Walsh, M Shah, ... Leukemia 33 (8), 1934-1943, 2019 | 40 | 2019 |
Comparing sequencing assays and human-machine analyses in actionable genomics for glioblastoma KO Wrzeszczynski, MO Frank, T Koyama, K Rhrissorrakrai, N Robine, ... Neurology Genetics 3 (4), 2017 | 38 | 2017 |
Use of chromatin remodeling ATPases as RNAi targets for parental control of western corn rootworm (Diabrotica virgifera virgifera) and Neotropical brown stink bug (Euschistus … E Fishilevich, AM Vélez, C Khajuria, MLF Frey, RL Hamm, H Wang, ... Insect biochemistry and molecular biology 71, 58-71, 2016 | 33 | 2016 |
Integrative genetic analysis of mouse and human AML identifies cooperating disease alleles MA Hatlen, K Arora, V Vacic, EA Grabowska, W Liao, B Riley-Gillis, ... Journal of Experimental Medicine 213 (1), 25-34, 2016 | 23 | 2016 |
Diverse alterations associated with resistance to KRAS (G12C) inhibition Y Zhao, YR Murciano-Goroff, JY Xue, A Ang, J Lucas, TT Mai, ... Nature 599 (7886), 679-683, 2021 | 20 | 2021 |
Deep whole-genome sequencing of 3 cancer cell lines on 2 sequencing platforms K Arora, M Shah, M Johnson, R Sanghvi, J Shelton, K Nagulapalli, ... Scientific reports 9 (1), 1-13, 2019 | 19 | 2019 |
Analytical validation of clinical whole-genome and transcriptome sequencing of patient-derived tumors for reporting targetable variants in cancer KO Wrzeszczynski, V Felice, A Abhyankar, L Kozon, H Geiger, D Manaa, ... The Journal of Molecular Diagnostics 20 (6), 822-835, 2018 | 18 | 2018 |
Identification of targetable BRAF ΔN486_P490 variant by whole-genome sequencing leading to dabrafenib-induced remission of a BRAF-mutant pancreatic adenocarcinoma KO Wrzeszczynski, S Rahman, MO Frank, K Arora, M Shah, H Geiger, ... Molecular Case Studies 5 (6), a004424, 2019 | 16 | 2019 |
Novel patterns of complex structural variation revealed across thousands of cancer genome graphs K Hadi, X Yao, JM Behr, A Deshpande, C Xanthopoulakis, J Rosiene, ... BioRxiv, 836296, 2019 | 14 | 2019 |
Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discov. 2018; 8 (9): 1112–29 H Tiriac, P Belleau, DD Engle, D Plenker, A Deschenes, TDD Somerville, ... Epub 2018/06/02. doi: 10.1158/2159-8290. CD-18-0349. PubMed PMID: 29853643, 0 | 14 | |
Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discov. 2018; 8 (9): 1112–1129. doi: 10.1158/2159-8290 H Tiriac, P Belleau, DD Engle, D Plenker, A Deschênes, TDD Somerville, ... CD-18-0349.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 14 | |