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Mutational heterogeneity in cancer and the search for new cancer-associated genes MS Lawrence, P Stojanov, P Polak, GV Kryukov, K Cibulskis, ... Nature 499 (7457), 214-218, 2013 | 6024 | 2013 |
A landscape of driver mutations in melanoma E Hodis, IR Watson, GV Kryukov, ST Arold, M Imielinski, JP Theurillat, ... Cell 150 (2), 251-263, 2012 | 3052 | 2012 |
Characterization of mammalian selenoproteomes GV Kryukov, S Castellano, SV Novoselov, AV Lobanov, O Zehtab, ... Science 300 (5624), 1439-1443, 2003 | 2909 | 2003 |
The mutational landscape of head and neck squamous cell carcinoma N Stransky, AM Egloff, AD Tward, AD Kostic, K Cibulskis, A Sivachenko, ... science 333 (6046), 1157-1160, 2011 | 2885 | 2011 |
Next-generation characterization of the cancer cell line encyclopedia M Ghandi, FW Huang, J Jané-Valbuena, GV Kryukov, CC Lo, ... Nature 569 (7757), 503-508, 2019 | 2752 | 2019 |
Defining a cancer dependency map A Tsherniak, F Vazquez, PG Montgomery, BA Weir, G Kryukov, ... Cell 170 (3), 564-576. e16, 2017 | 2381 | 2017 |
Highly recurrent TERT promoter mutations in human melanoma FW Huang, E Hodis, MJ Xu, GV Kryukov, L Chin, LA Garraway Science 339 (6122), 957-959, 2013 | 2187 | 2013 |
Punctuated evolution of prostate cancer genomes SC Baca, D Prandi, MS Lawrence, JM Mosquera, A Romanel, Y Drier, ... Cell 153 (3), 666-677, 2013 | 1468 | 2013 |
An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers SA Roberts, MS Lawrence, LJ Klimczak, SA Grimm, D Fargo, P Stojanov, ... Nature genetics 45 (9), 970-976, 2013 | 1281 | 2013 |
The genetic landscape of clinical resistance to RAF inhibition in metastatic melanoma EM Van Allen, N Wagle, A Sucker, DJ Treacy, CM Johannessen, ... Cancer discovery 4 (1), 94-109, 2014 | 979 | 2014 |
Pooled association tests for rare variants in exon-resequencing studies AL Price, GV Kryukov, PIW de Bakker, SM Purcell, J Staples, LJ Wei, ... The American Journal of Human Genetics 86 (6), 832-838, 2010 | 927 | 2010 |
An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules A Basu, NE Bodycombe, JH Cheah, EV Price, K Liu, GI Schaefer, ... Cell 154 (5), 1151-1161, 2013 | 809 | 2013 |
Quantitative proteomics of the cancer cell line encyclopedia DP Nusinow, J Szpyt, M Ghandi, CM Rose, ER McDonald, M Kalocsay, ... Cell 180 (2), 387-402. e16, 2020 | 781 | 2020 |
Most rare missense alleles are deleterious in humans: implications for complex disease and association studies GV Kryukov, LA Pennacchio, SR Sunyaev The American Journal of Human Genetics 80 (4), 727-739, 2007 | 729 | 2007 |
Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer A Vaishnavi, M Capelletti, AT Le, S Kako, M Butaney, D Ercan, S Mahale, ... Nature medicine 19 (11), 1469-1472, 2013 | 702 | 2013 |
Genome sequencing reveals insights into physiology and longevity of the naked mole rat EB Kim, X Fang, AA Fushan, Z Huang, AV Lobanov, L Han, SM Marino, ... Nature 479 (7372), 223-227, 2011 | 702 | 2011 |
Genomic copy number dictates a gene-independent cell response to CRISPR/Cas9 targeting AJ Aguirre, RM Meyers, BA Weir, F Vazquez, CZ Zhang, U Ben-David, ... Cancer discovery 6 (8), 914-929, 2016 | 682 | 2016 |
Somatic ERCC2 Mutations Correlate with Cisplatin Sensitivity in Muscle-Invasive Urothelial Carcinoma EM Van Allen, KW Mouw, P Kim, G Iyer, N Wagle, H Al-Ahmadie, C Zhu, ... Cancer discovery 4 (10), 1140-1153, 2014 | 621 | 2014 |
Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine EM Van Allen, N Wagle, P Stojanov, DL Perrin, K Cibulskis, S Marlow, ... Nature medicine 20 (6), 682-688, 2014 | 577 | 2014 |