Robert J Williams
Robert J Williams
Reader in Molecular and Cellular Neuroscience, University of Bath, UK
Verified email at bath.ac.uk - Homepage
TitleCited byYear
Flavonoids: antioxidants or signalling molecules?
RJ Williams, JPE Spencer, C Rice-Evans
Free radical biology and medicine 36 (7), 838-849, 2004
20212004
Flavonoids protect neurons from oxidized low-density-lipoprotein-induced apoptosis involving c-Jun N-terminal kinase (JNK), c-Jun and caspase-3
H Schroeter, JPE Spencer, C Rice-Evans, RJ Williams
Biochemical Journal 358 (3), 547-557, 2001
3812001
Flavonoids, cognition, and dementia: actions, mechanisms, and potential therapeutic utility for Alzheimer disease
RJ Williams, JPE Spencer
Free Radical Biology and Medicine 52 (1), 35-45, 2012
3772012
MAPK signaling in neurodegeneration: influences of flavonoids and of nitric oxide
H Schroeter, C Boyd, JPE Spencer, RJ Williams, E Cadenas, ...
Neurobiology of aging 23 (5), 861-880, 2002
3542002
Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease
M Thambisetty, A Simmons, L Velayudhan, A Hye, J Campbell, Y Zhang, ...
Archives of general psychiatry 67 (7), 739-748, 2010
3532010
Modulation of pro-survival Akt/protein kinase B and ERK1/2 signaling cascades by quercetin and its in vivo metabolites underlie their action on neuronal viability
JPE Spencer, C Rice-Evans, RJ Williams
Journal of Biological Chemistry 278 (37), 34783-34793, 2003
3462003
Intracellular metabolism and bioactivity of quercetin and its in vivo metabolites
JPE Spencer, GGC Kuhnle, RJ Williams, C Rice-Evans
Biochemical Journal 372 (1), 173-181, 2003
2572003
Activation of pro‐survival Akt and ERK1/2 signalling pathways underlie the anti‐apoptotic effects of flavanones in cortical neurons
D Vauzour, K Vafeiadou, C Rice‐Evans, RJ Williams, JPE Spencer
Journal of neurochemistry 103 (4), 1355-1367, 2007
2352007
Phosphatidylinositol 3‐kinase is a central mediator of NMDA receptor signalling to MAP kinase (Erk1/2), Akt/PKB and CREB in striatal neurones
MS Perkinton, J Ip, GL Wood, AJ Crossthwaite, RJ Williams
Journal of neurochemistry 80 (2), 239-254, 2002
2302002
Hydrogen peroxide‐mediated phosphorylation of ERK1/2, Akt/PKB and JNK in cortical neurones: dependence on Ca2+ and PI3‐kinase
AJ Crossthwaite, S Hasan, RJ Williams
Journal of neurochemistry 80 (1), 24-35, 2002
2202002
Neuroinflammation: modulation by flavonoids and mechanisms of action
JPE Spencer, K Vafeiadou, RJ Williams, D Vauzour
Molecular aspects of medicine 33 (1), 83-97, 2012
2142012
Phenolic antioxidants attenuate neuronal cell death following uptake of oxidized low-density lipoprotein
H Schroeter, RJ Williams, R Matin, L Iversen, CA Rice-Evans
Free Radical Biology and Medicine 29 (12), 1222-1233, 2000
2132000
Ca2+-permeable AMPA receptors induce phosphorylation of cAMP response element-binding protein through a phosphatidylinositol 3-kinase-dependent stimulation of the mitogen …
MS Perkinton, TS Sihra, RJ Williams
Journal of Neuroscience 19 (14), 5861-5874, 1999
2131999
Metals ions and neurodegeneration
F Molina-Holgado, RC Hider, A Gaeta, R Williams, P Francis
Biometals 20 (3-4), 639-654, 2007
2032007
Synaptic NMDA receptor activation stimulates α-secretase amyloid precursor protein processing and inhibits amyloid-β production
SE Hoey, RJ Williams, MS Perkinton
Journal of Neuroscience 29 (14), 4442-4460, 2009
1752009
Contrasting influences of glucuronidation and O-methylation of epicatechin on hydrogen peroxide-induced cell death in neurons and fibroblasts
JPE Spencer, H Schroeter, AJ Crossthwaithe, G Kuhnle, RJ Williams, ...
Free Radical Biology and Medicine 31 (9), 1139-1146, 2001
1722001
The citrus flavanone naringenin inhibits inflammatory signalling in glial cells and protects against neuroinflammatory injury
K Vafeiadou, D Vauzour, HY Lee, A Rodriguez-Mateos, RJ Williams, ...
Archives of Biochemistry and Biophysics 484 (1), 100-109, 2009
1702009
(‐) Epicatechin stimulates ERK‐dependent cyclic AMP response element activity and up‐regulates GluR2 in cortical neurons
H Schroeter, P Bahia, JPE Spencer, O Sheppard, M Rattray, E Cadenas, ...
Journal of neurochemistry 101 (6), 1596-1606, 2007
1552007
Phosphatidylinositol 3-kinase is a key mediator of central sensitization in painful inflammatory conditions
S Pezet, F Marchand, R D'Mello, J Grist, AK Clark, M Malcangio, ...
Journal of Neuroscience 28 (16), 4261-4270, 2008
1462008
Noxious stimulation induces Trk receptor and downstream ERK phosphorylation in spinal dorsal horn
S Pezet, M Malcangio, IJ Lever, MS Perkinton, SWN Thompson, ...
Molecular and Cellular Neuroscience 21 (4), 684-695, 2002
1402002
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