| Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity G Schiedner, N Morral, RJ Parks, Y Wu, SC Koopmans, C Langston, ... Nature genetics 18 (2), 180-183, 1998 | 913 | 1998 |
| Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons N Morral, W O’Neal, K Rice, M Leland, J Kaplan, PA Piedra, H Zhou, ... Proceedings of the National Academy of Sciences 96 (22), 12816-12821, 1999 | 497 | 1999 |
| The origin of the major cystic fibrosis mutation (ΔF508) in European populations N Morral, J Bertranpetit, X Estivill, V Nunes, T Casals, J Gimenez, A Reis, ... Nature genetics 7 (2), 169-175, 1994 | 474 | 1994 |
| High doses of a helper-dependent adenoviral vector yield supraphysiological levels of α 1-antitrypsin with negligible toxicity N Morral, RJ Parks, H Zhou, C Langston, G Schiedner, J Quinones, ... Human gene therapy 9 (18), 2709-2716, 1998 | 309 | 1998 |
| Use of a liver-specific promoter reduces immune response to the transgene in adenoviral vectors L Pastore, N Morral, H Zhou, R Garcia, RJ Parks, S Kochanek, FL Graham, ... Human gene therapy 10 (11), 1773-1781, 1999 | 212 | 1999 |
| Immune responses to reporter proteins and high viral dose limit duration of expression with adenoviral vectors: comparison of E2a wild type and E2a deleted vectors N Morral, W O'Neal, H Zhou, C Langston, A Beaudet Human gene therapy 8 (10), 1275-1286, 1997 | 207 | 1997 |
| Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons N Morral, WK O'Neal, K Rice, MM Leland, PA Piedra, E Aguilar-Córdova, ... Human gene therapy 13 (1), 143-154, 2002 | 200 | 2002 |
| Sterol regulatory element-binding protein-1 (SREBP-1) is required to regulate glycogen synthesis and gluconeogenic gene expression in mouse liver R Ruiz, V Jideonwo, M Ahn, S Surendran, VS Tagliabracci, Y Hou, ... Journal of Biological Chemistry 289 (9), 5510-5517, 2014 | 158 | 2014 |
| Toxicological Comparison of E2a-Deleted and First-Generation Adenoviral Vectors Expressing α1-Antitrypsin after Systemic Delivery WK O'Neal, H Zhou, N Morral, E Aguilar-Cordova, J Pestaner, C Langston, ... Human gene therapy 9 (11), 1587-1598, 1998 | 148 | 1998 |
| The search for south European cystic fibrosis mutations: identification of two new mutations, four variants, and intronic sequences P Gasparini, V Nunes, A Savoia, M Dognini, N Morral, A Gaona, ... Genomics 10 (1), 193-200, 1991 | 139 | 1991 |
| Development of a complementing cell line and a system for construction of adenovirus vectors with E1 and E2a deleted H Zhou, W O'Neal, N Morral, AL Beaudet Journal of virology 70 (10), 7030-7038, 1996 | 138 | 1996 |
| CA/GT microsatellite alleles within the cystic fibrosis transmembrane conductance regulator (CFTR) gene are not generated by unequal crossingover. N Morral, V Nunes, T Casals, X Estivill Genomics 10 (3), 692-698, 1991 | 124 | 1991 |
| Microsatellite haplotypes for cystic fibrosis: mutation frameworks and evolutionary tracers N Morral, V Nunes, T Casals, M Chillón, J Giménez, J Bertranpetit, ... Human molecular genetics 2 (7), 1015-1022, 1993 | 122 | 1993 |
| Toxicity associated with repeated administration of first-generation adenovirus vectors does not occur with a helper-dependent vector WK O’Neal, H Zhou, N Morral, C Langston, RJ Parks, FL Graham, ... Molecular medicine 6, 179-195, 2000 | 110 | 2000 |
| Gene therapy for inherited retinal and optic nerve degenerations NA Moore, N Morral, TA Ciulla, P Bracha Expert opinion on biological therapy 18 (1), 37-49, 2018 | 105 | 2018 |
| Multiplex PCR amplification of three microsatellites within the CFTR gene N Morral, X Estivill Genomics 13 (4), 1362-1364, 1992 | 104 | 1992 |
| Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice JM Irimia, CM Meyer, DM Segvich, S Surendran, AA DePaoli-Roach, ... Journal of Biological Chemistry 292 (25), 10455-10464, 2017 | 95 | 2017 |
| Novel targets and therapeutic strategies for type 2 diabetes N Morral Trends in Endocrinology & Metabolism 14 (4), 169-175, 2003 | 90 | 2003 |
| Molecular cloning and analysis of a yeast protein phosphatase with an unusual amino-terminal region. F Posas, A Casamayor, N Morral, J Ariño Journal of Biological Chemistry 267 (17), 11734-11740, 1992 | 89 | 1992 |
| Gene therapy for age-related macular degeneration NA Moore, P Bracha, RM Hussain, N Morral, TA Ciulla Expert opinion on biological therapy 17 (10), 1235-1244, 2017 | 88 | 2017 |
