Neutrophil elastase degrades cystic fibrosis transmembrane conductance regulator via calpains and disables channel function in vitro and in vivo M Le Gars, D Descamps, D Roussel, E Saussereau, L Guillot, M Ruffin, ... American journal of respiratory and critical care medicine 187 (2), 170-179, 2013 | 118 | 2013 |
Repair Process Impairment by Pseudomonas aeruginosa in Epithelial Tissues: Major Features and Potential Therapeutic Avenues M Ruffin, E Brochiero Frontiers in cellular and infection microbiology 9, 182, 2019 | 99 | 2019 |
MicroRNA-9 downregulates the ANO1 chloride channel and contributes to cystic fibrosis lung pathology F Sonneville, M Ruffin, C Coraux, N Rousselet, P Le Rouzic, ... Nature communications 8 (1), 710, 2017 | 77 | 2017 |
Anoctamin 1 dysregulation alters bronchial epithelial repair in cystic fibrosis M Ruffin, M Voland, S Marie, M Bonora, E Blanchard, S Blouquit-Laye, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (12 …, 2013 | 57 | 2013 |
Deleterious impact of Pseudomonas aeruginosa on cystic fibrosis transmembrane conductance regulator function and rescue in airway epithelial cells NTN Trinh, C Bilodeau, É Maillé, M Ruffin, MC Quintal, MY Desrosiers, ... European Respiratory Journal 45 (6), 1590-1602, 2015 | 53 | 2015 |
New insights about miRNAs in cystic fibrosis F Sonneville, M Ruffin, L Guillot, N Rousselet, P Le Rouzic, H Corvol, ... The American journal of pathology 185 (4), 897-908, 2015 | 53 | 2015 |
Vx-809/Vx-770 treatment reduces inflammatory response to Pseudomonas aeruginosa in primary differentiated cystic fibrosis bronchial epithelial cells M Ruffin, L Roussel, É Maillé, S Rousseau, E Brochiero American Journal of Physiology-Lung Cellular and Molecular Physiology 314 (4 …, 2018 | 48 | 2018 |
Quorum-sensing inhibition abrogates the deleterious impact of Pseudomonas aeruginosa on airway epithelial repair M Ruffin, C Bilodeau, É Maillé, SL LaFayette, GA McKay, NTN Trinh, ... The FASEB Journal 30 (9), 3011-3025, 2016 | 45 | 2016 |
Respiratory epithelial cells can remember infection: a proof-of-concept study J Bigot, L Guillot, J Guitard, M Ruffin, H Corvol, M Chignard, C Hennequin, ... The Journal of infectious diseases 221 (6), 1000-1005, 2020 | 36 | 2020 |
Staphylococcus aureus impairs sinonasal epithelial repair: effects in patients with chronic rhinosinusitis with nasal polyps and control subjects FCP Valera, M Ruffin, D Adam, É Maillé, B Ibrahim, J Berube, S Rousseau, ... Journal of Allergy and Clinical Immunology 143 (2), 591-603. e3, 2019 | 36 | 2019 |
Genetic variation in CFTR and modifier loci may modulate cystic fibrosis disease severity A Paranjapye, M Ruffin, A Harris, H Corvol Journal of Cystic Fibrosis 19, S10-S14, 2020 | 33 | 2020 |
CFTR rescue with VX-809 and VX-770 favors the repair of primary airway epithelial cell cultures from patients with class II mutations in the presence of Pseudomonas aeruginosa … D Adam, C Bilodeau, L Sognigbé, É Maillé, M Ruffin, E Brochiero Journal of Cystic Fibrosis 17 (6), 705-714, 2018 | 32 | 2018 |
Bronchial epithelial cells on the front line to fight lung infection-causing Aspergillus fumigatus J Bigot, L Guillot, J Guitard, M Ruffin, H Corvol, V Balloy, C Hennequin Frontiers in Immunology 11, 537755, 2020 | 26 | 2020 |
Azithromycin fails to reduce inflammation in cystic fibrosis airway epithelial cells V Saint-Criq, M Ruffin, C Rebeyrol, L Guillot, J Jacquot, A Clement, ... European journal of pharmacology 674 (1), 1-6, 2012 | 26 | 2012 |
Update on SLC6A14 in lung and gastrointestinal physiology and physiopathology: focus on cystic fibrosis M Ruffin, J Mercier, C Calmel, J Mésinèle, J Bigot, EN Sutanto, A Kicic, ... Cellular and Molecular Life Sciences 77, 3311-3323, 2020 | 25 | 2020 |
Quorum Sensing Down-Regulation Counteracts the Negative Impact of Pseudomonas aeruginosa on CFTR Channel Expression, Function and Rescue in Human … É Maillé, M Ruffin, D Adam, H Messaoud, SL Lafayette, G McKay, ... Frontiers in cellular and infection microbiology 7, 470, 2017 | 22 | 2017 |
Restoration of chloride efflux by azithromycin in airway epithelial cells of cystic fibrosis patients V Saint-Criq, C Rebeyrol, M Ruffin, T Roque, L Guillot, J Jacquot, ... Antimicrobial agents and chemotherapy 55 (4), 1792-1793, 2011 | 19 | 2011 |
Risk factors for Pseudomonas aeruginosa airway infection and lung function decline in children with cystic fibrosis J Mésinèle, M Ruffin, A Kemgang, L Guillot, PY Boëlle, H Corvol Journal of Cystic Fibrosis 21 (1), 45-51, 2022 | 14 | 2022 |
Modifier factors of cystic fibrosis phenotypes: a focus on modifier genes J Mésinèle, M Ruffin, L Guillot, H Corvol International Journal of Molecular Sciences 23 (22), 14205, 2022 | 13 | 2022 |
Flagellin From Pseudomonas aeruginosa Modulates SARS-CoV-2 Infectivity in Cystic Fibrosis Airway Epithelial Cells by Increasing TMPRSS2 Expression M Ruffin, J Bigot, C Calmel, J Mercier, M Givelet, J Oliva, A Pizzorno, ... Frontiers in Immunology 12, 714027, 2021 | 11 | 2021 |