|Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection|
S Balachandran, PC Roberts, LE Brown, H Truong, AK Pattnaik, ...
Immunity 13 (1), 129-141, 2000
|Activation of the dsRNA‐dependent protein kinase, PKR, induces apoptosis through FADD‐mediated death signaling|
S Balachandran, CN Kim, WC Yeh, TW Mak, K Bhalla, GN Barber
The EMBO journal 17 (23), 6888-6902, 1998
|Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes|
N Grandvaux, MJ Servant, GC Sen, S Balachandran, GN Barber, R Lin, ...
Journal of virology 76 (11), 5532-5539, 2002
|Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathway|
S Balachandran, PC Roberts, T Kipperman, KN Bhalla, RW Compans, ...
Journal of virology 74 (3), 1513-1523, 2000
|A FADD-dependent innate immune mechanism in mammalian cells|
S Balachandran, E Thomas, GN Barber
Nature 432 (7015), 401, 2004
|Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases|
RJ Thapa, S Nogusa, P Chen, JL Maki, A Lerro, M Andrake, GF Rall, ...
Proceedings of the National Academy of Sciences 110 (33), E3109-E3118, 2013
|Oncolytic activity of vesicular stomatitis virus is effective against tumors exhibiting aberrant p53, Ras, or myc function and involves the induction of apoptosis|
S Balachandran, M Porosnicu, GN Barber
Journal of virology 75 (7), 3474-3479, 2001
|Defective translational control facilitates vesicular stomatitis virus oncolysis|
S Balachandran, GN Barber
Cancer cell 5 (1), 51-65, 2004
|Adenoviral transfer of the melanoma differentiation-associated gene 7 (mda7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent …|
A Pataer, SA Vorburger, GN Barber, S Chada, AM Mhashilkar, ...
Cancer research 62 (8), 2239-2243, 2002
|The IRF-3 transcription factor mediates Sendai virus-induced apoptosis|
C Heylbroeck, S Balachandran, MJ Servant, C DeLuca, GN Barber, R Lin, ...
Journal of virology 74 (8), 3781-3792, 2000
|Vesicular stomatitis virus (VSV) therapy of tumors|
S Balachandran, GN Barber
IUBMB life 50 (2), 135-138, 2000
|RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition|
WJ Kaiser, LP Daley-Bauer, RJ Thapa, P Mandal, SB Berger, C Huang, ...
Proceedings of the National Academy of Sciences 111 (21), 7753-7758, 2014
|Characterization of two evolutionarily conserved, alternatively spliced nuclear phosphoproteins, NFAR-1 and-2, that function in mRNA processing and interact with the double …|
LR Saunders, DJ Perkins, S Balachandran, R Michaels, R Ford, ...
Journal of Biological Chemistry 276 (34), 32300-32312, 2001
|RIPK3 activates parallel pathways of MLKL-driven necroptosis and FADD-mediated apoptosis to protect against influenza A virus|
S Nogusa, RJ Thapa, CP Dillon, S Liedmann, TH Oguin III, JP Ingram, ...
Cell host & microbe 20 (1), 13-24, 2016
|NF-κB RelA subunit is crucial for early IFN-β expression and resistance to RNA virus replication|
J Wang, SH Basagoudanavar, X Wang, E Hopewell, R Albrecht, ...
The Journal of Immunology 185 (3), 1720-1729, 2010
|Cellular oxidative stress response controls the antiviral and apoptotic programs in dengue virus-infected dendritic cells|
D Olagnier, S Peri, C Steel, N van Montfoort, C Chiang, V Beljanski, ...
PLoS pathogens 10 (12), e1004566, 2014
|Inactivation of ribosomal protein L22 promotes transformation by induction of the stemness factor, Lin28B|
S Rao, SY Lee, A Gutierrez, J Perrigoue, RJ Thapa, Z Tu, JR Jeffers, ...
Blood 120 (18), 3764-3773, 2012
|The cellular protein P58IPK regulates influenza virus mRNA translation and replication through a PKR-mediated mechanism|
AG Goodman, JA Smith, S Balachandran, O Perwitasari, SC Proll, ...
Journal of virology 81 (5), 2221-2230, 2007
|RIPK1 and RIPK3 kinases promote cell-death-independent inflammation by Toll-like receptor 4|
M Najjar, D Saleh, M Zelic, S Nogusa, S Shah, A Tai, JN Finger, ...
Immunity 45 (1), 46-59, 2016
|Melanoma differentiation-associated gene-7 protein physically associates with the double-stranded RNA-activated protein kinase PKR|
A Pataer, SA Vorburger, S Chada, S Balachandran, GN Barber, JA Roth, ...
Molecular Therapy 11 (5), 717-723, 2005