| Development of a potent and selective chemical probe for the pleiotropic kinase CK2 CI Wells, DH Drewry, JE Pickett, A Tjaden, A Krämer, S Müller, L Gyenis, ... Cell chemical biology 28 (4), 546-558. e10, 2021 | 67 | 2021 |
| Optimization of pyrazolo [1, 5-a] pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor A Krämer, CG Kurz, BT Berger, IE Celik, A Tjaden, FA Greco, S Knapp, ... European Journal of Medicinal Chemistry 208, 112770, 2020 | 29 | 2020 |
| Image-based annotation of chemogenomic libraries for phenotypic screening A Tjaden, A Chaikuad, E Kowarz, R Marschalek, S Knapp, M Schröder, ... Molecules 27 (4), 1439, 2022 | 22 | 2022 |
| A triple farnesoid X receptor and peroxisome proliferator-activated receptor α/δ activator reverses hepatic fibrosis in diet-induced NASH in mice P Heitel, G Faudone, M Helmstädter, J Schmidt, A Kaiser, A Tjaden, ... Communications chemistry 3 (1), 174, 2020 | 14 | 2020 |
| Illuminating the Dark: Highly Selective Inhibition of Serine/Threonine Kinase 17A with Pyrazolo[1,5-a]pyrimidine-Based Macrocycles CG Kurz, F Preuss, A Tjaden, M Cusack, JA Amrhein, D Chatterjee, ... Journal of Medicinal Chemistry 65 (11), 7799-7817, 2022 | 10 | 2022 |
| High-content live-cell multiplex screen for chemogenomic compound annotation based on nuclear morphology A Tjaden, RT Giessmann, S Knapp, M Schröder, S Müller STAR protocols 3 (4), 101791, 2022 | 8 | 2022 |
| Shifting the selectivity of pyrido [2, 3-d] pyrimidin-7 (8H)-one inhibitors towards the salt-inducible kinase (SIK) subfamily M Rak, R Tesch, LM Berger, E Shevchenko, M Raab, A Tjaden, R Zhubi, ... European Journal of Medicinal Chemistry 254, 115347, 2023 | 5 | 2023 |
| Development of a selective dual discoidin domain receptor (DDR)/p38 kinase chemical probe S Röhm, BT Berger, M Schröder, D Chatterjee, S Mathea, AC Joerger, ... Journal of Medicinal Chemistry 64 (18), 13451-13474, 2021 | 4 | 2021 |
| Discovery of 3-Amino-1H-pyrazole-Based Kinase Inhibitors to Illuminate the Understudied PCTAIRE Family JA Amrhein, LM Berger, A Tjaden, A Krämer, L Elson, T Tolvanen, ... International Journal of Molecular Sciences 23 (23), 14834, 2022 | 3 | 2022 |
| Compilation and evaluation of a fatty acid mimetics screening library JHM Ehrler, S Brunst, A Tjaden, W Kilu, J Heering, V Hernandez-Olmos, ... Biochemical Pharmacology 204, 115191, 2022 | 3 | 2022 |
| A machine learning and live-cell imaging tool kit uncovers small molecules induced phospholipidosis H Hu, A Tjaden, S Knapp, AA Antolin, S Müller Cell chemical biology 30 (12), 1634-1651. e6, 2023 | 2 | 2023 |
| Characterization of Cellular Viability Using Label-Free Brightfield Live-Cell Imaging L Elson, A Tjaden, S Knapp, S Müller Chemogenomics: Methods and Protocols, 75-88, 2023 | | 2023 |
| Annotation of the Effect of Chemogenomic Compounds on Cell Health Using High-Content Microscopy in Live-Cell Mode A Tjaden, S Knapp, S Müller Chemogenomics: Methods and Protocols, 59-73, 2023 | | 2023 |
| Check Chapter 6 updates L Elson, A Tjaden, S Knapp, S Müller Chemogenomics: Methods and Protocols 2706, 75, 2023 | | 2023 |
| Deep Annotation of Donated Chemical Probes (DCP) in Organotypic Human Liver Cultures and Patient-Derived Organoids from Tumor and Normal Colorectum C Tredup, B Ndreshkjana, NS Schneider, A Tjaden, AM Kemas, ... ACS Chemical Biology 18 (4), 822-836, 2023 | | 2023 |
| IPP/CNRS-A017: A chemical probe for human dihydroorotate dehydrogenase (hDHODH) A Krämer, A Tjaden, B Ndreshkjana, C Tredup, HF Farin, S Knapp, ... Current Research in Chemical Biology 2, 100034, 2022 | | 2022 |
| Current Research in Chemical Biology A Krämer, A Tjaden, B Ndreshkjana, C Tredup, HF Farin, S Knapp, ... | | |
| Workflow of Pillar 1 towards the Assembly of Chemogenomic-Compound Sets S Röhm, C Tredup, TDN Ngu, S Haeberle, A Tjaden, V Nemec, S Müller, ... | | |
Stefan KnappUniversity of FrankfurtVerified email at pharmchem.uni-frankfurt.de
