Doug Speed
Doug Speed
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Cited by
Cited by
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
C Curtis, SP Shah, SF Chin, G Turashvili, OM Rueda, MJ Dunning, ...
Nature 486 (7403), 346-352, 2012
Improved heritability estimation from genome-wide SNPs
D Speed, G Hemani, MR Johnson, DJ Balding
The American Journal of Human Genetics 91 (6), 1011-1021, 2012
Transient structural variations have strong effects on quantitative traits and reproductive isolation in fission yeast
DC Jeffares, C Jolly, M Hoti, D Speed, L Shaw, C Rallis, F Balloux, ...
Nature communications 8 (1), 14061, 2017
Reevaluation of SNP heritability in complex human traits
D Speed, N Cai, Ucleb Consortium, MR Johnson, S Nejentsev, ...
Nature genetics 49 (7), 986-992, 2017
MultiBLUP: improved SNP-based prediction for complex traits
D Speed, DJ Balding
Genome research 24 (9), 1550-1557, 2014
Relatedness in the post-genomic era: is it still useful?
D Speed, DJ Balding
Nature Reviews Genetics 16 (1), 33-44, 2015
Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies
Nature communications 9 (1), 5269, 2018
SumHer better estimates the SNP heritability of complex traits from summary statistics
D Speed, DJ Balding
Nature genetics 51 (2), 277-284, 2019
Genetic correlations among psychiatric and immune‐related phenotypes based on genome‐wide association data
DS Tylee, J Sun, JL Hess, MA Tahir, E Sharma, R Malik, BB Worrall, ...
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 177 …, 2018
The genomic and phenotypic diversity of Schizosaccharomyces pombe
DC Jeffares, C Rallis, A Rieux, D Speed, M Převorovský, T Mourier, ...
Nature genetics 47 (3), 235-241, 2015
Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies
RJL Anney, A Avbersek, D Balding, L Baum, F Becker, SF Berkovic, ...
The Lancet Neurology, 2014
Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus
MR Johnson, J Behmoaras, L Bottolo, ML Krishnan, K Pernhorst, ...
Nature communications 6 (1), 6031, 2015
Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease
MR Johnson, K Shkura, SR Langley, A Delahaye-Duriez, P Srivastava, ...
Nature neuroscience 19 (2), 223-232, 2016
Evaluating and improving heritability models using summary statistics
D Speed, J Holmes, DJ Balding
Nature Genetics 52 (4), 458-462, 2020
Graph pangenome captures missing heritability and empowers tomato breeding
Y Zhou, Z Zhang, Z Bao, H Li, Y Lyu, Y Zan, Y Wu, L Cheng, Y Fang, K Wu, ...
Nature 606 (7914), 527-534, 2022
Investigating the association between body fat and depression via Mendelian randomization
MS Speed, OH Jefsen, AD Børglum, D Speed, SD Østergaard
Translational psychiatry 9 (1), 184, 2019
Describing the genetic architecture of epilepsy through heritability analysis
D Speed, TJ O’Brien, A Palotie, K Shkura, AG Marson, DJ Balding, ...
Brain 137 (10), 2680-2689, 2014
GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI
A Couto Alves, NMG De Silva, V Karhunen, U Sovio, S Das, HR Taal, ...
Science Advances 5 (9), eaaw3095, 2019
Improved genetic prediction of complex traits from individual-level data or summary statistics
Q Zhang, F Privé, B Vilhjálmsson, D Speed
Nature communications 12 (1), 4192, 2021
Genetic complexity of Crohn’s disease in two large Ashkenazi Jewish families
AP Levine, N Pontikos, ER Schiff, L Jostins, D Speed, LB Lovat, JC Barrett, ...
Gastroenterology 151 (4), 698-709, 2016
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