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Shuo-Chien Ling
Shuo-Chien Ling
Подтвержден адрес электронной почты в домене nus.edu.sg
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Процитировано
Год
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
106062021
Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis
SC Ling, M Polymenidou, DW Cleveland
Neuron 79 (3), 416-438, 2013
17412013
Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43
M Polymenidou, C Lagier-Tourenne, KR Hutt, SC Huelga, J Moran, ...
Nature neuroscience 14 (4), 459-468, 2011
13432011
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs
C Lagier-Tourenne, M Polymenidou, KR Hutt, AQ Vu, M Baughn, ...
Nature neuroscience 15 (11), 1488-1497, 2012
8022012
Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration
C Lagier-Tourenne, M Baughn, F Rigo, S Sun, P Liu, HR Li, J Jiang, ...
Proceedings of the National Academy of Sciences 110 (47), E4530-E4539, 2013
6532013
Gain of toxicity from ALS/FTD-linked repeat expansions in C9ORF72 is alleviated by antisense oligonucleotides targeting GGGGCC-containing RNAs
J Jiang, Q Zhu, TF Gendron, S Saberi, M McAlonis-Downes, A Seelman, ...
Neuron 90 (3), 535-550, 2016
5492016
ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS
SC Ling, CP Albuquerque, JS Han, C Lagier-Tourenne, S Tokunaga, ...
Proceedings of the National Academy of Sciences 107 (30), 13318-13323, 2010
5152010
ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43
ES Arnold, SC Ling, SC Huelga, C Lagier-Tourenne, M Polymenidou, ...
Proceedings of the National Academy of Sciences 110 (8), E736-E745, 2013
4862013
ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP
S Sun, SC Ling, J Qiu, CP Albuquerque, Y Zhou, S Tokunaga, H Li, H Qiu, ...
Nature communications 6 (1), 6171, 2015
2402015
Transport of Drosophila fragile X mental retardation protein-containing ribonucleoprotein granules by kinesin-1 and cytoplasmic dynein
SC Ling, PS Fahrner, WT Greenough, VI Gelfand
Proceedings of the National Academy of Sciences 101 (50), 17428-17433, 2004
2202004
ALS/FTD-linked mutation in FUS suppresses intra-axonal protein synthesis and drives disease without nuclear loss-of-function of FUS
J López-Erauskin, T Tadokoro, MW Baughn, B Myers, ...
Neuron 100 (4), 816-830. e7, 2018
2032018
Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS
S Sun, Y Sun, SC Ling, L Ferraiuolo, M McAlonis-Downes, Y Zou, ...
Proceedings of the National Academy of Sciences 112 (50), E6993-E7002, 2015
1802015
Muscle expression of mutant androgen receptor accounts for systemic and motor neuron disease phenotypes in spinal and bulbar muscular atrophy
CJ Cortes, SC Ling, LT Guo, G Hung, T Tsunemi, L Ly, S Tokunaga, ...
Neuron 82 (2), 295-307, 2014
1662014
Microtubule binding by dynactin is required for microtubule organization but not cargo transport
H Kim, SC Ling, GC Rogers, C Kural, PR Selvin, SL Rogers, VI Gelfand
The Journal of cell biology 176 (5), 641-651, 2007
1612007
Fused in Sarcoma (FUS) Protein Lacking Nuclear Localization Signal (NLS) and Major RNA Binding Motifs Triggers Proteinopathy and Severe Motor Phenotype in Transgenic Mice*♦
TA Shelkovnikova, OM Peters, AV Deykin, N Connor-Robson, ...
Journal of biological chemistry 288 (35), 25266-25274, 2013
1422013
Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS
JC Mitchell, R Constable, E So, C Vance, E Scotter, L Glover, ...
Acta neuropathologica communications 3, 1-16, 2015
982015
A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons
F Angenstein, AM Evans, RE Settlage, ST Moran, SC Ling, AY Klintsova, ...
Journal of Neuroscience 22 (20), 8827-8837, 2002
982002
Cell-autonomous requirement of TDP-43, an ALS/FTD signature protein, for oligodendrocyte survival and myelination
J Wang, WY Ho, K Lim, J Feng, G Tucker-Kellogg, KA Nave, SC Ling
Proceedings of the National Academy of Sciences 115 (46), E10941-E10950, 2018
752018
Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis
SC Ling, SG Dastidar, S Tokunaga, WY Ho, K Lim, H Ilieva, PA Parone, ...
elife 8, e40811, 2019
732019
Synaptic paths to neurodegeneration: the emerging role of TDP-43 and FUS in synaptic functions
SC Ling
Neural plasticity 2018, 2018
712018
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Статьи 1–20