Stromal modulators of TGF-β in cancer B Costanza, IA Umelo, J Bellier, V Castronovo, A Turtoi Journal of clinical medicine 6 (1), 7, 2017 | 172 | 2017 |
Asporin is a fibroblast-derived TGF-β1 inhibitor and a tumor suppressor associated with good prognosis in breast cancer P Maris, A Blomme, AP Palacios, B Costanza, A Bellahcène, E Bianchi, ... PLoS medicine 12 (9), e1001871, 2015 | 123 | 2015 |
Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis MJ Nokin, F Durieux, P Peixoto, B Chiavarina, O Peulen, A Blomme, ... elife 5, e19375, 2016 | 118 | 2016 |
Murine stroma adopts a human-like metabolic phenotype in the PDX model of colorectal cancer and liver metastases A Blomme, G Van Simaeys, G Doumont, B Costanza, J Bellier, Y Otaka, ... Oncogene 37 (9), 1237-1250, 2018 | 79 | 2018 |
Myoferlin regulates cellular lipid metabolism and promotes metastases in triple-negative breast cancer A Blomme, B Costanza, P De Tullio, M Thiry, G Van Simaeys, S Boutry, ... Oncogene 36 (15), 2116-2130, 2017 | 64 | 2017 |
Myoferlin is a novel exosomal protein and functional regulator of cancer-derived exosomes A Blomme, K Fahmy, O Peulen, B Costanza, M Fontaine, I Struman, ... Oncotarget 7 (50), 83669, 2016 | 63 | 2016 |
Transforming growth factor beta‐induced, an extracellular matrix interacting protein, enhances glycolysis and promotes pancreatic cancer cell migration B Costanza, G Rademaker, A Tiamiou, P De Tullio, J Leenders, ... International journal of cancer 145 (6), 1570-1584, 2019 | 62 | 2019 |
Metastatic colorectal cancer cells maintain the TGFβ program and use TGFBI to fuel angiogenesis B Chiavarina, B Costanza, R Ronca, A Blomme, S Rezzola, P Chiodelli, ... Theranostics 11 (4), 1626, 2021 | 52 | 2021 |
Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness G Rademaker, V Hennequiere, L Brohee, MJ Nokin, P Lovinfosse, ... Oncogene 37 (32), 4398-4412, 2018 | 52 | 2018 |
HDAC7 inhibition resets STAT3 tumorigenic activity in human glioblastoma independently of EGFR and PTEN: new opportunities for selected targeted therapies P Peixoto, A Blomme, B Costanza, R Ronca, S Rezzola, AP Palacios, ... Oncogene 35 (34), 4481-4494, 2016 | 35 | 2016 |
Methylglyoxal scavengers resensitize KRAS-mutated colorectal tumors to cetuximab J Bellier, MJ Nokin, M Caprasse, A Tiamiou, A Blomme, JL Scheijen, ... Cell reports 30 (5), 1400-1416. e6, 2020 | 31 | 2020 |
Myoferlin contributes to the metastatic phenotype of pancreatic cancer cells by enhancing their migratory capacity through the control of oxidative phosphorylation G Rademaker, B Costanza, S Anania, F Agirman, N Maloujahmoum, ... Cancers 11 (6), 853, 2019 | 27 | 2019 |
Human colon cancer cells highly express myoferlin to maintain a fit mitochondrial network and escape p53-driven apoptosis G Rademaker, B Costanza, J Bellier, M Herfs, R Peiffer, F Agirman, ... Oncogenesis 8 (3), 21, 2019 | 25 | 2019 |
LSD1-directed therapy affects glioblastoma tumorigenicity by deregulating the protective ATF4-dependent integrated stress response S Faletti, D Osti, E Ceccacci, C Richichi, B Costanza, L Nicosia, ... Science Translational Medicine 13 (623), eabf7036, 2021 | 22 | 2021 |
Innovative methods for biomarker discovery in the evaluation and development of cancer precision therapies IA Umelo, B Costanza, V Castronovo Cancer and Metastasis Reviews 37, 125-145, 2018 | 22 | 2018 |
Innovative methodology for the identification of soluble biomarkers in fresh tissues B Costanza, A Turtoi, A Bellahcene, T Hirano, O Peulen, A Blomme, ... Oncotarget 9 (12), 10665, 2018 | 13 | 2018 |
Correction: Human colon cancer cells highly express myoferlin to maintain a fit mitochondrial network and escape p53-driven apoptosis G Rademaker, B Costanza, J Bellier, M Herfs, R Peiffer, F Agirman, ... Oncogenesis 12 (1), 11, 2023 | 1 | 2023 |
Paladin, overexpressed in colon cancer, is required for actin polymerisation and liver metastasis dissemination G Rademaker, B Costanza, S Pyr dit Ruys, R Peiffer, F Agirman, ... Oncogenesis 11 (1), 42, 2022 | 1 | 2022 |
Correction: Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis MJ Nokin, F Durieux, P Peixoto, B Chiavarina, O Peulen, A Blomme, ... Elife 13, e96613, 2024 | | 2024 |
P02. 26. B METABOLIC PLASTICITY IN GLIOBLASTOMA TUMOR-INITIATING CELL AND RESISTANCE TO LSD1-DIRECTED THERAPY G Marotta, B Costanza, D Osti, S Faletti, E Zaccheroni, C Richichi, ... Neuro-Oncology 25 (Supplement_2), ii36-ii36, 2023 | | 2023 |