| Tutorial: a guide to performing polygenic risk score analyses SW Choi, TSH Mak, PF O’Reilly Nature Protocols 15 (9), 2759-2772, 2020 | 1260 | 2020 |
| PRSice-2: Polygenic Risk Score software for biobank-scale data SW Choi, PF O'Reilly GigaScience 8 (7), giz082, 2019 | 1079 | 2019 |
| Polygenic scores via penalized regression on summary statistics TSH Mak, RM Porsch, SW Choi, X Zhou, PC Sham Genetic epidemiology 41 (6), 469-480, 2017 | 368 | 2017 |
| Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank JRI Coleman, WJ Peyrot, KL Purves, KAS Davis, C Rayner, SW Choi, ... Molecular psychiatry 25 (7), 1430-1446, 2020 | 145 | 2020 |
| Genome-wide gene-environment analyses of depression and reported lifetime traumatic experiences in UK Biobank JRI Coleman, KL Purves, KAS Davis, C Rayner, SW Choi, C Hübel, ... bioRxiv, 247353, 2018 | 145* | 2018 |
| Patient-specific induced-pluripotent stem cells-derived cardiomyocytes recapitulate the pathogenic phenotypes of dilated cardiomyopathy due to a novel DES mutation identified … HF Tse, JCY Ho, SW Choi, YK Lee, AW Butler, KM Ng, CW Siu, ... Human molecular genetics 22 (7), 1395-1403, 2013 | 117 | 2013 |
| Association of polygenic risk for attention-deficit/hyperactivity disorder with co-occurring traits and disorders E Du Rietz, J Coleman, K Glanville, SW Choi, PF O’Reilly, J Kuntsi Biological Psychiatry: Cognitive Neuroscience and Neuroimaging 3 (7), 635-643, 2018 | 109 | 2018 |
| Multi–polygenic score approach to identifying individual vulnerabilities associated with the risk of exposure to bullying T Schoeler, SW Choi, F Dudbridge, J Baldwin, L Duncan, CM Cecil, ... JAMA psychiatry 76 (7), 730-738, 2019 | 101 | 2019 |
| Genetic analysis of amyotrophic lateral sclerosis identifies contributing pathways and cell types S Saez-Atienzar, S Bandres-Ciga, RG Langston, JJ Kim, SW Choi, ... Science advances 7 (3), eabd9036, 2021 | 65 | 2021 |
| Amelioration of X-linked related autophagy failure in Danon disease with DNA methylation inhibitor KM Ng, PY Mok, AW Butler, JCY Ho, SW Choi, YK Lee, WH Lai, KW Au, ... Circulation, CIRCULATIONAHA. 115.019847, 2016 | 43 | 2016 |
| Novel pre-mRNA splicing of intronically integrated HBV generates oncogenic chimera in hepatocellular carcinoma YT Chiu, JKL Wong, SW Choi, KMF Sze, DWH Ho, LK Chan, JMF Lee, ... Journal of hepatology 64 (6), 1256-1264, 2016 | 43 | 2016 |
| Genetic comorbidity between major depression and cardio‐metabolic traits, stratified by age at onset of major depression SP Hagenaars, JRI Coleman, SW Choi, H Gaspar, MJ Adams, ... American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 183 …, 2020 | 42 | 2020 |
| Studying individual risk factors for self-harm in the UK Biobank: A polygenic scoring and Mendelian randomisation study KX Lim, F Rijsdijk, SP Hagenaars, A Socrates, SW Choi, JRI Coleman, ... PLoS medicine 17 (6), e1003137, 2020 | 38 | 2020 |
| Cannabis use, depression and self‐harm: phenotypic and genetic relationships K Hodgson, JRI Coleman, SP Hagenaars, KL Purves, K Glanville, ... Addiction 115 (3), 482-492, 2020 | 37 | 2020 |
| Genetic sensitivity analysis: adjusting for genetic confounding in epidemiological associations JB Pingault, F Rijsdijk, T Schoeler, SW Choi, S Selzam, E Krapohl, ... PLoS genetics 17 (6), e1009590, 2021 | 35 | 2021 |
| Classical human leukocyte antigen alleles and C4 haplotypes are not significantly associated with depression KP Glanville, JRI Coleman, KB Hanscombe, J Euesden, SW Choi, ... Biological psychiatry 87 (5), 419-430, 2020 | 26 | 2020 |
| The power of pathway-based polygenic risk scores SW Choi, J Garcia-Gonzalez, Y Ruan, HM Wu, J Johnson, C Hoggart, ... | 14 | 2021 |
| Familial influences on Neuroticism and Education in the UK Biobank R Cheesman, J Coleman, C Rayner, KL Purves, G Morneau-Vaillancourt, ... Behavior Genetics, 1-10, 2019 | 14 | 2019 |
| Identification of novel locus associated with coronary artery aneurysms and validation of loci for susceptibility to Kawasaki disease C Hoggart, C Shimizu, R Galassini, VJ Wright, H Shailes, E Bellos, ... European Journal of Human Genetics 29 (12), 1734-1744, 2021 | 13 | 2021 |
| A guide to performing Polygenic Risk Score analyses SW Choi, TSH Mak, PF O’Reilly BioRxiv, 416545, 2018 | 13* | 2018 |
Paul F O'ReillyAssociate Professor in Statistical Genetics, Icahn School of Medicine, Mount Sinai NYCVerified email at mssm.edu
