| The natural polyamine spermine functions directly as a free radical scavenger HC Ha, NS Sirisoma, P Kuppusamy, JL Zweier, PM Woster, RA Casero Jr Proceedings of the National Academy of Sciences 95 (19), 11140-11145, 1998 | 1188 | 1998 |
| Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia T Schenk, WC Chen, S Göllner, L Howell, L Jin, K Hebestreit, HU Klein, ... Nature medicine 18 (4), 605-611, 2012 | 701 | 2012 |
| Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis AC Goodwin, CED Shields, S Wu, DL Huso, XQ Wu, TR Murray-Stewart, ... Proceedings of the National Academy of Sciences 108 (37), 15354-15359, 2011 | 585 | 2011 |
| Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents: decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by … P Schmiedlin-Ren, DJ Edwards, ME Fitzsimmons, K He, KS Lown, ... Drug Metabolism and Disposition 25 (11), 1228-1233, 1997 | 487 | 1997 |
| Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes Y Huang, E Greene, T Murray Stewart, AC Goodwin, SB Baylin, ... Proceedings of the National Academy of Sciences 104 (19), 8023-8028, 2007 | 368 | 2007 |
| The role of polyamine catabolism in polyamine analogue-induced programmed cell death HC Ha, PM Woster, JD Yager, RA Casero Jr Proceedings of the National Academy of Sciences 94 (21), 11557-11562, 1997 | 355 | 1997 |
| Polyamines and cancer: implications for chemotherapy and chemoprevention SL Nowotarski, PM Woster, RA Casero Expert reviews in molecular medicine 15, e3, 2013 | 327 | 2013 |
| 6′, 7′‐Dihydroxybergamottin in grapefruit juice and Seville orange juice: effects on cyclosporine disposition, enterocyte CYP3A4, and P‐glycoprotein DJ Edwards, ME Fitzsimmons, EG Schuetz, K Yasuda, MP Ducharme, ... Clinical Pharmacology & Therapeutics 65 (3), 237-244, 1999 | 322 | 1999 |
| Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide JE Rider, A Hacker, CA Mackintosh, AE Pegg, PM Woster, RA Casero Amino acids 33, 231-240, 2007 | 314 | 2007 |
| Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure Y Wang, W Devereux, PM Woster, TM Stewart, A Hacker, RA Casero Jr Cancer research 61 (14), 5370-5373, 2001 | 311 | 2001 |
| Identification of 6', 7'-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice. DJ Edwards, FH Bellevue, PM Woster Drug Metabolism and Disposition 24 (12), 1287-1290, 1996 | 297 | 1996 |
| Terminally alkylated polyamine analogues as chemotherapeutic agents RA Casero, PM Woster Journal of medicinal chemistry 44 (1), 1-26, 2001 | 296 | 2001 |
| Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes Y Huang, TM Stewart, Y Wu, SB Baylin, LJ Marton, B Perkins, RJ Jones, ... Clinical cancer research 15 (23), 7217-7228, 2009 | 250 | 2009 |
| Recent advances in the development of polyamine analogues as antitumor agents RA Casero Jr, PM Woster Journal of medicinal chemistry 52 (15), 4551-4573, 2009 | 213 | 2009 |
| A role for bioactivation and covalent binding within epidermal keratinocytes in sulfonamide-induced cutaneous drug reactions TP Reilly, LH Lash, MA Doll, DW Hein, PM Woster, CK Svensson Journal of Investigative Dermatology 114 (6), 1164-1173, 2000 | 189 | 2000 |
| Polyamine catabolism and oxidative damage TM Stewart, TT Dunston, PM Woster, RA Casero Journal of Biological Chemistry 293 (48), 18736-18745, 2018 | 177 | 2018 |
| Targeting polyamine metabolism for cancer therapy and prevention TR Murray-Stewart, PM Woster, RA Casero Jr Biochemical journal 473 (19), 2937-2953, 2016 | 167 | 2016 |
| (Bis) urea and (bis) thiourea inhibitors of lysine-specific demethylase 1 as epigenetic modulators SK Sharma, Y Wu, N Steinbergs, ML Crowley, AS Hanson, RA Casero Jr, ... Journal of medicinal chemistry 53 (14), 5197-5212, 2010 | 163 | 2010 |
| Properties of purified recombinant human polyamine oxidase, PAOh1/SMO Y Wang, T Murray-Stewart, W Devereux, A Hacker, B Frydman, ... Biochemical and biophysical research communications 304 (4), 605-611, 2003 | 159 | 2003 |
| Spermine oxidase SMO (PAOh1), Not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines A Pledgie, Y Huang, A Hacker, Z Zhang, PM Woster, NE Davidson, ... Journal of Biological Chemistry 280 (48), 39843-39851, 2005 | 156 | 2005 |
Yi HuangUniversity of Iowa Carver College of MedicineVerified email at uiowa.edu
