Patrick Woster
TitleCited byYear
The natural polyamine spermine functions directly as a free radical scavenger
HC Ha, NS Sirisoma, P Kuppusamy, JL Zweier, PM Woster, RA Casero
Proceedings of the National Academy of Sciences 95 (19), 11140-11145, 1998
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia
T Schenk, WC Chen, S Göllner, L Howell, L Jin, K Hebestreit, HU Klein, ...
Nature medicine 18 (4), 605, 2012
Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents: decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by …
P Schmiedlin-Ren, DJ Edwards, ME Fitzsimmons, K He, KS Lown, ...
Drug Metabolism and Disposition 25 (11), 1228-1233, 1997
The role of polyamine catabolism in polyamine analogue-induced programmed cell death
HC Ha, PM Woster, JD Yager, RA Casero
Proceedings of the National Academy of Sciences 94 (21), 11557-11562, 1997
Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes
Y Huang, E Greene, TM Stewart, AC Goodwin, SB Baylin, PM Woster, ...
Proceedings of the National Academy of Sciences 104 (19), 8023-8028, 2007
6′, 7′‐Dihydroxybergamottin in grapefruit juice and Seville orange juice: effects on cyclosporine disposition, enterocyte CYP3A4, and P‐glycoprotein
DJ Edwards, ME Fitzsimmons, EG Schuetz, K Yasuda, MP Ducharme, ...
Clinical Pharmacology & Therapeutics 65 (3), 237-244, 1999
Terminally alkylated polyamine analogues as chemotherapeutic agents
RA Casero, PM Woster
Journal of medicinal chemistry 44 (1), 1-26, 2001
Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure
Y Wang, W Devereux, PM Woster, TM Stewart, A Hacker, RA Casero
Cancer Research 61 (14), 5370-5373, 2001
Identification of 6', 7'-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice.
DJ Edwards, FH Bellevue, PM Woster
Drug metabolism and disposition 24 (12), 1287-1290, 1996
Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes
Y Huang, TM Stewart, Y Wu, SB Baylin, LJ Marton, B Perkins, RJ Jones, ...
Clinical cancer research 15 (23), 7217-7228, 2009
Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis
AC Goodwin, CED Shields, S Wu, DL Huso, XQ Wu, TR Murray-Stewart, ...
Proceedings of the National Academy of Sciences 108 (37), 15354-15359, 2011
Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide
JE Rider, A Hacker, CA Mackintosh, AE Pegg, PM Woster, RA Casero
Amino acids 33 (2), 231-240, 2007
Polyamines and cancer: implications for chemotherapy and chemoprevention
SL Nowotarski, PM Woster, RA Casero
Expert reviews in molecular medicine 15, 2013
Recent advances in the development of polyamine analogues as antitumor agents
RA Casero Jr, PM Woster
Journal of medicinal chemistry 52 (15), 4551-4573, 2009
A role for bioactivation and covalent binding within epidermal keratinocytes in sulfonamide-induced cutaneous drug reactions
TP Reilly, LH Lash, MA Doll, DW Hein, PM Woster, CK Svensson
Journal of Investigative Dermatology 114 (6), 1164-1173, 2000
Properties of purified recombinant human polyamine oxidase, PAOh1/SMO
Y Wang, T Murray-Stewart, W Devereux, A Hacker, B Frydman, ...
Biochemical and biophysical research communications 304 (4), 605-611, 2003
Spermine oxidase SMO (PAOh1), Not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines
A Pledgie, Y Huang, A Hacker, Z Zhang, PM Woster, NE Davidson, ...
Journal of Biological Chemistry 280 (48), 39843-39851, 2005
(Bis) urea and (bis) thiourea inhibitors of lysine-specific demethylase 1 as epigenetic modulators
SK Sharma, Y Wu, N Steinbergs, ML Crowley, AS Hanson, RA Casero Jr, ...
Journal of medicinal chemistry 53 (14), 5197-5212, 2010
Synthesis and evaluation of unsymmetrically substituted polyamine analogs as modulators of human spermidine/spermine-N1-acetyltransferase (SSAT) and as potential antitumor agents
NH Saab, EE West, NC Bieszk, CV Preuss, AR Mank, RA Casero Jr, ...
Journal of medicinal chemistry 36 (20), 2998-3004, 1993
System and method for bi-ventricular fusion pacing
MRS Hill
US Patent 6,871,096, 2005
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