Patrick Woster
TitleCited byYear
The natural polyamine spermine functions directly as a free radical scavenger
HC Ha, NS Sirisoma, P Kuppusamy, JL Zweier, PM Woster, RA Casero
Proceedings of the National Academy of Sciences 95 (19), 11140-11145, 1998
5631998
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia
T Schenk, WC Chen, S Göllner, L Howell, L Jin, K Hebestreit, HU Klein, ...
Nature medicine 18 (4), 605, 2012
4292012
Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents: decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by …
P Schmiedlin-Ren, DJ Edwards, ME Fitzsimmons, K He, KS Lown, ...
Drug Metabolism and Disposition 25 (11), 1228-1233, 1997
4151997
The role of polyamine catabolism in polyamine analogue-induced programmed cell death
HC Ha, PM Woster, JD Yager, RA Casero
Proceedings of the National Academy of Sciences 94 (21), 11557-11562, 1997
3261997
Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes
Y Huang, E Greene, TM Stewart, AC Goodwin, SB Baylin, PM Woster, ...
Proceedings of the National Academy of Sciences 104 (19), 8023-8028, 2007
3032007
6′, 7′‐Dihydroxybergamottin in grapefruit juice and Seville orange juice: effects on cyclosporine disposition, enterocyte CYP3A4, and P‐glycoprotein
DJ Edwards, ME Fitzsimmons, EG Schuetz, K Yasuda, MP Ducharme, ...
Clinical Pharmacology & Therapeutics 65 (3), 237-244, 1999
2901999
Terminally alkylated polyamine analogues as chemotherapeutic agents
RA Casero, PM Woster
Journal of medicinal chemistry 44 (1), 1-26, 2001
2622001
Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure
Y Wang, W Devereux, PM Woster, TM Stewart, A Hacker, RA Casero
Cancer Research 61 (14), 5370-5373, 2001
2612001
Identification of 6', 7'-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice.
DJ Edwards, FH Bellevue, PM Woster
Drug metabolism and disposition 24 (12), 1287-1290, 1996
2611996
Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes
Y Huang, TM Stewart, Y Wu, SB Baylin, LJ Marton, B Perkins, RJ Jones, ...
Clinical cancer research 15 (23), 7217-7228, 2009
2132009
Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis
AC Goodwin, CED Shields, S Wu, DL Huso, XQ Wu, TR Murray-Stewart, ...
Proceedings of the National Academy of Sciences 108 (37), 15354-15359, 2011
1972011
Spermine and spermidine mediate protection against oxidative damage caused by hydrogen peroxide
JE Rider, A Hacker, CA Mackintosh, AE Pegg, PM Woster, RA Casero
Amino acids 33 (2), 231-240, 2007
1802007
Polyamines and cancer: implications for chemotherapy and chemoprevention
SL Nowotarski, PM Woster, RA Casero
Expert reviews in molecular medicine 15, 2013
1722013
Recent advances in the development of polyamine analogues as antitumor agents
RA Casero Jr, PM Woster
Journal of medicinal chemistry 52 (15), 4551-4573, 2009
1632009
A role for bioactivation and covalent binding within epidermal keratinocytes in sulfonamide-induced cutaneous drug reactions
TP Reilly, LH Lash, MA Doll, DW Hein, PM Woster, CK Svensson
Journal of Investigative Dermatology 114 (6), 1164-1173, 2000
1622000
Properties of purified recombinant human polyamine oxidase, PAOh1/SMO
Y Wang, T Murray-Stewart, W Devereux, A Hacker, B Frydman, ...
Biochemical and biophysical research communications 304 (4), 605-611, 2003
1502003
Spermine oxidase SMO (PAOh1), Not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines
A Pledgie, Y Huang, A Hacker, Z Zhang, PM Woster, NE Davidson, ...
Journal of Biological Chemistry 280 (48), 39843-39851, 2005
1282005
(Bis) urea and (bis) thiourea inhibitors of lysine-specific demethylase 1 as epigenetic modulators
SK Sharma, Y Wu, N Steinbergs, ML Crowley, AS Hanson, RA Casero Jr, ...
Journal of medicinal chemistry 53 (14), 5197-5212, 2010
1242010
Synthesis and evaluation of unsymmetrically substituted polyamine analogs as modulators of human spermidine/spermine-N1-acetyltransferase (SSAT) and as potential antitumor agents
NH Saab, EE West, NC Bieszk, CV Preuss, AR Mank, RA Casero Jr, ...
Journal of medicinal chemistry 36 (20), 2998-3004, 1993
1141993
System and method for bi-ventricular fusion pacing
MRS Hill
US Patent 6,871,096, 2005
1132005
The system can't perform the operation now. Try again later.
Articles 1–20