|Tracking the evolution of non–small-cell lung cancer|
M Jamal-Hanjani, GA Wilson, N McGranahan, NJ Birkbak, TBK Watkins, ...
New England Journal of Medicine 376 (22), 2109-2121, 2017
|Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution|
C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ...
Nature 545 (7655), 446, 2017
|Allele-specific HLA loss and immune escape in lung cancer evolution|
N McGranahan, R Rosenthal, CT Hiley, AJ Rowan, TBK Watkins, ...
Cell 171 (6), 1259-1271. e11, 2017
|Fc-optimized anti-CD25 depletes tumor-infiltrating regulatory T cells and synergizes with PD-1 blockade to eradicate established tumors|
FA Vargas, AJS Furness, I Solomon, K Joshi, L Mekkaoui, MH Lesko, ...
Immunity 46 (4), 577-586, 2017
|Fc effector function contributes to the activity of human anti-CTLA-4 antibodies|
FA Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ...
Cancer Cell 33 (4), 649-663. e4, 2018
|The relevance of human stem cell-derived organoid models for epithelial translational medicine|
RE Hynds, A Giangreco
Stem Cells, 2013
|Rapid expansion of human epithelial stem cells suitable for airway tissue engineering|
CR Butler, RE Hynds, KHC Gowers, DDH Lee, JM Brown, C Crowley, ...
American Journal of Respiratory and Critical Care Medicine, 2016
|Divergent cellular pathways of hippocampal memory consolidation and reconsolidation|
JLC Lee, RE Hynds
Hippocampus 23 (3), 233-244, 2013
|Targeting EGFR signalling in chronic lung disease: therapeutic challenges and opportunities|
S Vallath, RE Hynds, L Succony, SM Janes, A Giangreco
European Respiratory Journal 44 (2), 513-522, 2014
|Surface modification of a POSS-nanocomposite material to enhance cellular integration of a synthetic bioscaffold|
C Crowley, P Klanrit, CR Butler, A Varanou, M Platé, RE Hynds, ...
Biomaterials 83, 283-293, 2016
|Tracheal Replacement Therapy with a Stem Cell‐Seeded Graft: Lessons from Compassionate Use Application of a GMP‐Compliant Tissue‐Engineered Medicine|
MJ Elliott, CR Butler, A Varanou‐Jenkins, L Partington, C Carvalho, ...
Stem Cells Translational Medicine 6 (6), 1458-1464, 2017
|Vacuum-assisted decellularization: an accelerated protocol to generate tissue-engineered human tracheal scaffolds|
CR Butler, RE Hynds, C Crowley, KHC Gowers, L Partington, NJ Hamilton, ...
Biomaterials 124, 95-105, 2017
|A comparison of tracheal scaffold strategies for pediatric transplantation in a rabbit model|
EF Maughan, CR Butler, C Crowley, GZ Teoh, M Den Hondt, NJ Hamilton, ...
The Laryngoscope 127 (12), E449-E457, 2017
|Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions|
VH Teixeira, CP Pipinikas, A Pennycuick, H Lee-Six, D Chandrasekharan, ...
Nature Medicine, 2019
|Autologous Cell Seeding in Tracheal Tissue Engineering|
EF Maughan, RE Hynds, TJ Proctor, SM Janes, M Elliott, MA Birchall, ...
Current Stem Cell Reports 3 (4), 279-289, 2017
|Regenerating human epithelia with cultured stem cells: feeder cells, organoids and beyond|
RE Hynds, P Bonfanti, SM Janes
EMBO Molecular Medicine 10 (2), 139-150, 2018
|Expansion of Human Airway Basal Stem Cells and Their Differentiation as 3D Tracheospheres|
RE Hynds, CR Butler, SM Janes, A Giangreco
Methods in Molecular Biology, 2016
|Airway tissue engineering for congenital laryngotracheal disease|
E Maughan, F Lesage, CR Butler, RE Hynds, R Hewitt, SM Janes, ...
Seminars in Pediatric Surgery 25 (3), 186-190, 2016
|The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis|
HV Woodcock, JD Eley, D Guillotin, M Platé, CB Nanthakumar, M Martufi, ...
Nature Communications 10 (1), 6, 2019
|Optimized isolation and expansion of human airway epithelial basal cells from endobronchial biopsy samples|
KHC Gowers, RE Hynds, RM Thakrar, B Carroll, MA Birchall, SM Janes
Journal of Tissue Engineering and Regenerative Medicine 12 (1), e313-e317, 2018