|RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3|
L Tavares, E Dimitrova, D Oxley, J Webster, R Poot, J Demmers, ...
Cell 148 (4), 664-678, 2012
|The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements|
S Schoenfelder, M Furlan-Magaril, B Mifsud, F Tavares-Cadete, R Sugar, ...
Genome research 25 (4), 582-597, 2015
|Polycomb repressive complex PRC1 spatially constrains the mouse embryonic stem cell genome|
S Schoenfelder, R Sugar, A Dimond, BM Javierre, H Armstrong, B Mifsud, ...
Nature genetics 47 (10), 1179-1186, 2015
|Histone demethylases in chromatin biology and beyond|
E Dimitrova, AH Turberfield, RJ Klose
EMBO reports 16 (12), 1620-1639, 2015
|The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9|
A Dhayalan, R Tamas, I Bock, A Tattermusch, E Dimitrova, S Kudithipudi, ...
Human molecular genetics 20 (11), 2195-2203, 2011
|The SET1 complex selects actively transcribed target genes via multivalent interaction with CpG island chromatin|
DA Brown, V Di Cerbo, A Feldmann, J Ahn, S Ito, NP Blackledge, ...
Cell reports 20 (10), 2313-2327, 2017
|A continuous protein methyltransferase (G9a) assay for enzyme activity measurement and inhibitor screening|
A Dhayalan, E Dimitrova, P Rathert, A Jeltsch
Journal of Biomolecular Screening 14 (9), 1129-1133, 2009
|FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment|
E Dimitrova, T Kondo, A Feldmann, M Nakayama, Y Koseki, R Konietzny, ...
Elife 7, e37084, 2018
|A CpG island-encoded mechanism protects genes from premature transcription termination|
AL Hughes, AT Szczurek, JR Kelley, A Lastuvkova, AH Turberfield, ...
Nature Communications 14 (1), 726, 2023
|Distinct roles for CKM–Mediator in controlling Polycomb-dependent chromosomal interactions and priming genes for induction|
E Dimitrova, A Feldmann, RH van der Weide, KD Flach, A Lastuvkova, ...
Nature structural & molecular biology 29 (10), 1000-1010, 2022
|CDK-Mediator and FBXL19 prime developmental genes for activation by promoting atypical regulatory interactions|
A Feldmann, E Dimitrova, A Kenney, A Lastuvkova, RJ Klose
Nucleic Acids Research 48 (6), 2942-2955, 2020
|Changes in PRC1 activity during interphase modulate lineage transition in pluripotent cells|
HG Asenjo, M Alcazar-Fabra, M Espinosa-Martínez, L Lopez-Onieva, ...
Nature Communications 14 (1), 180, 2023
|Polycomb sustains promoters in a deep OFF-state by limiting PIC formation to counteract transcription|
AT Szczurek, E Dimitrova, JR Kelley, RJ Klose
bioRxiv, 2023.06. 13.544762, 2023
|Polycomb repression during S/G2 phases restrain initiation of cell differentiation to the G1 phase of the cell cycle|
HG Asenjo, M Alcazar-Fabra, M Espinosa, L Lopez-Onieva, A Gallardo, ...
bioRxiv, 2022.07. 26.501502, 2022
|Recruitment and interplay between distinct polycomb repressive complexes 1 in embryonic stem cells and during neural lineage commitment|
University of Cambridge, 2013