| Protein homeostasis imposes a barrier on functional integration of horizontally transferred genes in bacteria S Bershtein, AWR Serohijos, S Bhattacharyya, M Manhart, JM Choi, W Mu, ... PLoS genetics 11 (10), e1005612, 2015 | 81 | 2015 |
| Accessibility of the Shine-Dalgarno sequence dictates N-terminal codon bias in E. coli S Bhattacharyya, WM Jacobs, BV Adkar, J Yan, W Zhang, EI Shakhnovich Molecular cell 70 (5), 894-905. e5, 2018 | 68 | 2018 |
| Transient protein-protein interactions perturb E. coli metabolome and cause gene dosage toxicity S Bhattacharyya, S Bershtein, J Yan, T Argun, AI Gilson, SA Trauger, ... elife 5, e20309, 2016 | 60 | 2016 |
| Optimization of lag phase shapes the evolution of a bacterial enzyme BV Adkar, M Manhart, S Bhattacharyya, J Tian, M Musharbash, ... Nature ecology & evolution 1 (6), 0149, 2017 | 51 | 2017 |
| Packing in molten globules and native states S Bhattacharyya, R Varadarajan Current Opinion in Structural Biology 23 (1), 11-21, 2013 | 48 | 2013 |
| Design of a non-glycosylated outer domain-derived HIV-1 gp120 immunogen that binds to CD4 and induces neutralizing antibodies S Bhattacharyya, RE Rajan, Y Swarupa, U Rathore, A Verma, ... Journal of biological chemistry 285 (35), 27100-27110, 2010 | 39 | 2010 |
| Systems-level response to point mutations in a core metabolic enzyme modulates genotype-phenotype relationship S Bershtein, JM Choi, S Bhattacharyya, B Budnik, E Shakhnovich Cell reports 11 (4), 645-656, 2015 | 38 | 2015 |
| Refolding and simultaneous purification by three‐phase partitioning of recombinant proteins from inclusion bodies S Raghava, B Barua, PK Singh, M Das, L Madan, S Bhattacharyya, ... Protein Science 17 (11), 1987-1997, 2008 | 36 | 2008 |
| Design of an Escherichia coli expressed HIV-1 gp120 fragment immunogen that binds to b12 and induces broad and potent neutralizing antibodies S Bhattacharyya, P Singh, U Rathore, M Purwar, D Wagner, H Arendt, ... Journal of Biological Chemistry 288 (14), 9815-9825, 2013 | 30 | 2013 |
| Designed cyclic permutants of HIV-1 gp120: implications for envelope trimer structure and immunogen design P Saha, S Bhattacharyya, S Kesavardhana, ER Miranda, PSS Ali, ... Biochemistry 51 (9), 1836-1847, 2012 | 25 | 2012 |
| Substrate inhibition imposes fitness penalty at high protein stability BV Adkar, S Bhattacharyya, AI Gilson, W Zhang, EI Shakhnovich Proceedings of the National Academy of Sciences 116 (23), 11265-11274, 2019 | 17 | 2019 |
| Design and characterization of stabilized derivatives of human CD4D12 and CD4D1 P Saha, B Barua, S Bhattacharyya, MM Balamurali, WR Schief, D Baker, ... Biochemistry 50 (37), 7891-7900, 2011 | 16 | 2011 |
| Strategy for purifying maltose binding protein fusion proteins by affinity precipitation S Raghava, S Aquil, S Bhattacharyya, R Varadarajan, MN Gupta Journal of Chromatography A 1194 (1), 90-95, 2008 | 16 | 2008 |
| Bacterially expressed HIV-1 gp120 outer-domain fragment immunogens with improved stability and affinity for CD4-binding site neutralizing antibodies U Rathore, M Purwar, VS Vignesh, R Das, AA Kumar, S Bhattacharyya, ... Journal of Biological Chemistry 293 (39), 15002-15020, 2018 | 15 | 2018 |
| Design, display and immunogenicity of HIV1 gp120 fragment immunogens on virus-like particles M Purwar, JK Pokorski, P Singh, S Bhattacharyya, H Arendt, J DeStefano, ... Vaccine 36 (42), 6345-6353, 2018 | 12 | 2018 |
| Metabolic response to point mutations reveals principles of modulation of in vivo enzyme activity and phenotype S Bhattacharyya, S Bershtein, BV Adkar, J Woodard, EI Shakhnovich Molecular Systems Biology 17 (6), e10200, 2021 | 10 | 2021 |
| Allosteric communication between ligand binding domains modulates substrate inhibition in adenylate kinase D Scheerera, BV Adkar, S Bhattacharyya, D Levya, M Iljinaa, I Rivena, ... Proceedings of the National Academy of Sciences 120 (18), e2219855120, 2023 | 4 | 2023 |
| Gene dosage experiments in enterobacteriaceae using Arabinose-regulated promoters S Bhattacharyya, S Bershtein, EI Shakhnovich Bio-protocol 7 (14), 2017 | 4 | 2017 |
| HIV-1 Envelope Based Fragments SK Phogat, R Varadarajan, S Bhattacharyya US Patent App. 13/038,828, 2011 | 4 | 2011 |
| Targeting The CD4 Biniding Site In HIV-1 Immunogen Design S Bhattacharyya | | 2016 |
Bharat V AdkarHarvard UniversityVerified email at fas.harvard.edu
