Pavitra Kannan
TitleCited byYear
Imaging the function of P-glycoprotein with radiotracers: pharmacokinetics and in vivo applications
P Kannan, C John, SS Zoghbi, C Halldin, MM Gottesman, RB Innis, ...
Clinical Pharmacology & Therapeutics 86 (4), 368-377, 2009
1812009
Comparison of [11C]-(R)-PK 11195 and [11C] PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging …
WC Kreisl, M Fujita, Y Fujimura, N Kimura, KJ Jenko, P Kannan, J Hong, ...
Neuroimage 49 (4), 2924-2932, 2010
1732010
The “specific” P-glycoprotein inhibitor tariquidar is also a substrate and an inhibitor for breast cancer resistance protein (BCRP/ABCG2)
P Kannan, S Telu, S Shukla, SV Ambudkar, VW Pike, C Halldin, ...
ACS Chemical Neuroscience 2 (2), 82-89, 2010
1182010
Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Semisynthesis of Salvinicins A and B and Other Chemical Transformations of Salvinorin A
WW Harding, M Schmidt, K Tidgewell, P Kannan, KG Holden, B Gilmour, ...
Journal of natural products 69 (1), 107-112, 2006
742006
Synthetic studies of neoclerodane diterpenes from Salvia divinorum: Selective modification of the furan ring
WW Harding, M Schmidt, K Tidgewell, P Kannan, KG Holden, CM Dersch, ...
Bioorganic & medicinal chemistry letters 16 (12), 3170-3174, 2006
622006
Synthesis of salvinorin A analogues as opioid receptor probes
K Tidgewell, WW Harding, A Lozama, H Cobb, K Shah, P Kannan, ...
Journal of natural products 69 (6), 914-918, 2006
602006
Radiodefluorination of 3-fluoro-5-(2-(2-[18F](fluoromethyl)-thiazol-4-yl) ethynyl) benzonitrile ([18F] SP203), a radioligand for imaging brain metabotropic glutamate subtype-5 …
HU Shetty, SS Zoghbi, FG Siméon, JS Liow, AK Brown, P Kannan, ...
Journal of Pharmacology and Experimental Therapeutics 327 (3), 727-735, 2008
522008
Collateral sensitivity of multidrug-resistant cells to the orphan drug tiopronin
AS Goldsborough, MD Handley, AE Dulcey, KM Pluchino, P Kannan, ...
Journal of medicinal chemistry 54 (14), 4987-4997, 2011
392011
Lysosomal trapping of a radiolabeled substrate of P-glycoprotein as a mechanism for signal amplification in PET
P Kannan, KR Brimacombe, WC Kreisl, JS Liow, SS Zoghbi, S Telu, ...
Proceedings of the National Academy of Sciences 108 (6), 2593-2598, 2011
392011
N-desmethyl-loperamide is selective for P-glycoprotein among three ATP-binding cassette transporters at the blood-brain barrier
P Kannan, KR Brimacombe, SS Zoghbi, JS Liow, C Morse, AK Taku, ...
Drug Metabolism and Disposition 38 (6), 917-922, 2010
342010
Regulation of O2 consumption by the PI3K and mTOR pathways contributes to tumor hypoxia
CJ Kelly, K Hussien, E Fokas, P Kannan, RJ Shipley, TM Ashton, ...
Radiotherapy and Oncology, 2014
272014
Estimating oxygen distribution from vasculature in three-dimensional tumour tissue
DR Grimes, P Kannan, DR Warren, B Markelc, R Bates, R Muschel, ...
Journal of The Royal Society Interface 13 (116), 20160070, 2016
262016
The Role of Oxygen in Avascular Tumor Growth
DR Grimes, P Kannan, A McIntyre, A Kavanagh, A Siddiky, S Wigfield, ...
PLoS ONE 11 (4), e0153692, 2016
262016
Tariquidar is an Inhibitor and Not a Substrate of Human and Mouse P-glycoprotein
LD Weidner, KL Fung, P Kannan, JK Moen, JS Kumar, J Mulder, RB Innis, ...
Drug Metabolism and Disposition 44 (2), 275-282, 2016
252016
Factors that limit PET imaging of P-glycoprotein density at the blood-brain barrier
P Kannan, VW Pike, C Halldin, O Langer, MM Gottesman, RB Innis, ...
Molecular pharmaceutics, 2013
192013
The adenosine A2A receptor agonist, CGS-21680, blocks excessive rearing, acquisition of wheel running, and increases nucleus accumbens CREB phosphorylation in chronically food …
S Cabeza de Vaca, P Kannan, Y Pan, N Jiang, Y Sun, KD Carr
Brain research 1142, 100-109, 2007
182007
Bayesian calibration, validation and uncertainty quantification for predictive modelling of tumour growth: a tutorial
J Collis, AJ Connor, M Paczkowski, P Kannan, J Pitt-Francis, HM Byrne, ...
Bulletin of mathematical biology 79 (4), 939-974, 2017
152017
Effects of ketoconazole on the biodistribution and metabolism of [11C] loperamide and [11C]- N-desmethyl-loperamide in wild-type and P-gp knockout mice
N Seneca, SS Zoghbi, HU Shetty, E Tuan, P Kannan, A Taku, RB Innis, ...
Nuclear medicine and biology 37 (3), 335-345, 2010
132010
Kinetic brain analysis and whole-body imaging in monkey of [11C] MNPA, a dopamine agonist radioligand
N Seneca, M Skinbjerg, SS Zoghbi, JS Liow, RL Gladding, J Hong, ...
Neuroimage 41, T139, 2008
122008
Kinetic brain analysis and whole‐body imaging in monkey of [11C] MNPA: A dopamine agonist radioligand
N Seneca, M Skinbjerg, SS Zoghbi, JS Liow, RL Gladding, J Hong, ...
Synapse 62 (9), 700-709, 2008
122008
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Articles 1–20