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Yi Ting (Kayla) Lien
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Physiologically based pharmacokinetic modeling of monoclonal antibodies in pediatric populations using PK-Sim
S Basu, YT Lien, V Vozmediano, JF Schlender, T Eissing, S Schmidt, ...
Frontiers in pharmacology 11, 868, 2020
362020
Vancomycin in peritoneal dialysis: clinical pharmacology considerations in therapy
E Lam, YT Lien, WK Kraft, B Piraino, V Vozmediano, S Schmidt, J Zhang
Peritoneal Dialysis International 40 (4), 384-393, 2020
292020
From cold to hot: changing perceptions and future opportunities for quantitative systems pharmacology modeling in cancer immunotherapy
V Lemaire, D Bassen, M Reed, R Song, S Khalili, YT Lien, L Huang, ...
Clinical Pharmacology & Therapeutics 113 (5), 963-972, 2023
122023
Applications of advanced natural language processing for clinical pharmacology
JC Hsu, M Wu, C Kim, B Vora, YT Lien, A Jindal, K Yoshida, S Kawakatsu, ...
Clinical Pharmacology & Therapeutics 115 (4), 786-794, 2024
102024
Investigating clinically adequate concentrations of oseltamivir carboxylate in end-stage renal disease patients undergoing hemodialysis using a population pharmacokinetic approach
MA Kamal, KYT Lien, R Robson, V Subramoney, B Clinch, CR Rayner, ...
Antimicrobial Agents and Chemotherapy 59 (11), 6774-6781, 2015
72015
Establishment of a Disease‐Drug Trial Model for Postmenopausal Osteoporosis: A Zoledronic Acid Case Study
YT Lien, K Madrasi, S Samant, MJ Kim, F Li, L Li, Y Wang, S Schmidt
The Journal of Clinical Pharmacology 60, S86-S102, 2020
62020
Identification of new oral dosing regimens for the neuraminidase inhibitor oseltamivir in patients with moderate and severe renal impairment
MA Kamal, BJ Brennan, V Subramoney, YT Lien, PN Morcos, N Frey, ...
Clinical Pharmacology in Drug Development 4 (5), 326-336, 2015
52015
The quest for balance between capturing data and model complexity: A quantitative clinical pharmacology approach applied to monoclonal antibodies
MA Pressly, LA Peletier, S Zheng, VD Sharma, YT Lien, W Wang, H Zhou, ...
CPT: pharmacometrics & systems pharmacology 12 (5), 639-655, 2023
42023
Quantitative pharmacology and individualized therapy strategies in development of therapeutic proteins for immune-mediated inflammatory diseases
H Zhou, DR Mould
John Wiley & Sons, 2019
22019
Concentration QTc analysis of giredestrant: Overcoming QT/heart rate confounding in the presence of drug‐induced heart rate changes
L Brooks, M Dolton, J Langenhorst, K Yoshida, YT Lien, V Malhi, C Li, ...
Clinical and Translational Science 16 (5), 823-834, 2023
12023
The effect of monoclonal antibodies pharmacokinetics on the tumor cells dynamics: a bifurcation analysis
A Hajihosseini, F Maleki, YT Lien, V Vozmediano, S Schmidt
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 45, S45-S46, 2018
12018
Abstract PO4-04-11: Exposure–response analyses of GO39932: a Phase Ia/b study of giredestrant in estrogen receptor-positive, HER2-negative, locally advanced or metastatic …
K Jhaveri, YT Lien, N Turner, E Lim, M Cannon, R Anziano, J Langenhorst, ...
Cancer Research 84 (9_Supplement), PO4-04-11-PO4-04-11, 2024
2024
UGT1A4 Polymorphism is not Associated with a Clinically Relevant Change in Giredestrant Exposure
V Malhi, M Nowicka, YC Chen, P Agarwal, M Waldvogel, YTK Lien, ...
Cancer Chemotherapy and Pharmacology, 1-6, 2024
2024
Supplementary Material: The quest for balance between capturing data and model complexity: a quantitative clinical pharmacology approach applied to monoclonal antibodies
MA Pressly, LA Peletier, S Zheng, VD Sharma, YTK Lien, W Wang, ...
Target 1 (2), 3, 2022
2022
Application of Pharmacometric Principles for Enhanced Decision Making in Special Patient Populations
YT Lien
University of Florida, 2020
2020
Application of Pharmacometrics and Systems Pharmacology to Current and Emerging Biologics in Inflammatory Bowel Diseases
S Ait‐Oudhia, YT Lien, S Basu, L Lesko, S Schmidt
Quantitative Pharmacology and Individualized Therapy Strategies in …, 2019
2019
Pharmacokinetics of intraperitoneal vancomycin in patients on automated peritoneal dialysis
E Lam, YTK Lien, V Vozmediano, S Schmidt, WK Kraft, J Zhang
2019
A STATISTICAL BIOEQUIVALENCE METHOD TO REDUCE SAMPLE SIZE FOR PARALLEL BE STUDY DESIGN: A CASE EXAMPLE FOR LONG-ACTING INJECTABLE DRUGS.
Y Lien, M Hu, L Fang, MJ Kim, L Zhao
CLINICAL PHARMACOLOGY & THERAPEUTICS 103, S37-S37, 2018
2018
Quantification of postmenopausal osteoporosis population: An system pharmacology approach using bisphosphonates
YT Lien, K Madrasi, S Samant, MJ Kim, F Li, S Voss, T Kehoe, L Li, ...
JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 44, S120-S120, 2017
2017
Exposure–response analyses of GO39932: a Phase Ia/b study of giredestrant in estrogen receptor-positive, HER2-negative, locally advanced or metastatic breast cancer
KL Jhaveri, YTK Lien, NC Turner, E Lim, M Cannon, R Anziano, ...
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