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Demis Menolfi
Demis Menolfi
Verified email at cumc.columbia.edu
Title
Cited by
Cited by
Year
ATM, ATR and DNA-PKcs kinases—the lessons from the mouse models: inhibition≠ deletion
D Menolfi, S Zha
Cell & Bioscience 10 (1), 8, 2020
1612020
Essential roles of the Smc5/6 complex in replication through natural pausing sites and endogenous DNA damage tolerance
D Menolfi, A Delamarre, A Lengronne, P Pasero, D Branzei
Molecular cell 60 (6), 835-846, 2015
1302015
DNA bending facilitates the error‐free DNA damage tolerance pathway and upholds genome integrity
V Gonzalez‐Huici, B Szakal, M Urulangodi, I Psakhye, F Castellucci, ...
The EMBO journal 33 (4), 327-340, 2014
752014
Local regulation of the Srs2 helicase by the SUMO-like domain protein Esc2 promotes recombination at sites of stalled replication
M Urulangodi, M Sebesta, D Menolfi, B Szakal, J Sollier, A Sisakova, ...
Genes & development 29 (19), 2067-2080, 2015
672015
During replication stress, non-SMC element 5 (NSE5) is required for Smc5/6 protein complex functionality at stalled forks
DE Bustard, D Menolfi, K Jeppsson, LG Ball, SC Dewey, K Shirahige, ...
Journal of Biological Chemistry 287 (14), 11374-11383, 2012
632012
Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA
D Menolfi, W Jiang, BJ Lee, T Moiseeva, Z Shao, V Estes, MG Frattini, ...
Nature communications 9 (1), 5351, 2018
442018
Rtt107 is a multi-functional scaffold supporting replication progression with partner SUMO and ubiquitin ligases
LE Hang, J Peng, W Tan, B Szakal, D Menolfi, Z Sheng, K Lobachev, ...
Molecular cell 60 (2), 268-279, 2015
342015
Smc5/6 functions with Sgs1-Top3-Rmi1 to complete chromosome replication at natural pause sites
S Agashe, CR Joseph, TAC Reyes, D Menolfi, M Giannattasio, ...
Nature communications 12 (1), 2111, 2021
212021
ATM, DNA-PKcs and ATR: shaping development through the regulation of the DNA damage responses
D Menolfi, S Zha
Genome Instability & Disease 1 (2), 47-68, 2020
132020
The cancer-associated ATM R3008H mutation reveals the link between ATM activation and its exchange
M Milanovic, LM Houghton, D Menolfi, JH Lee, K Yamamoto, Y Li, BJ Lee, ...
Cancer research 81 (2), 426-437, 2021
72021
DNA damage–induced phosphorylation of CtIP at a conserved ATM/ATR site T855 promotes lymphomagenesis in mice
XS Wang, D Menolfi, F Wu-Baer, M Fangazio, SN Meyer, Z Shao, Y Wang, ...
Proceedings of the National Academy of Sciences 118 (38), e2105440118, 2021
62021
ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion
D Menolfi, BJ Lee, H Zhang, W Jiang, NE Bowen, Y Wang, J Zhao, ...
Nature communications 14 (1), 3618, 2023
52023
FATC domain deletion compromises ATM protein stability, blocks lymphocyte development, and promotes lymphomagenesis
M Milanovic, Z Shao, VM Estes, XS Wang, D Menolfi, X Lin, BJ Lee, J Xu, ...
The Journal of Immunology 206 (6), 1228-1239, 2021
52021
Asymmetric distribution of parental H3K9me3 in S phase silences L1 elements
Z Li, S Duan, X Hua, X Xu, Y Li, D Menolfi, H Zhou, C Lu, S Zha, SP Goff, ...
Nature 623 (7987), 643-651, 2023
42023
DNA-PKcs kinase activity orchestrates both end-processing and end-ligation
D Menolfi, S Zha
Trends in Cell Biology 32 (2), 91-93, 2022
42022
G2/M chromosome transactions essentially relying on Smc5/6
D Branzei, D Menolfi
Cell Cycle 15 (5), 611-612, 2016
32016
70 years of the DNA double helix: An interview with Daniela Rhodes
D Rhodes
Molecular Cell 83 (8), 1200-1203, 2023
22023
Targeting BRCA-mutated tumors in mitosis
D Menolfi, S Zha
Nature Cancer 2 (12), 1296-1297, 2021
12021
Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts
X Lin, D Gupta, A Vaitsiankova, SK Bhandari, KSK Leung, D Menolfi, ...
bioRxiv, 2024.03. 12.584665, 2024
2024
Using Cell Cycle-Restricted Alleles to Study the Chromatin Dynamics and Functions of the Structural Maintenance of Chromosomes (SMC) Complexes In Vivo
D Menolfi, D Branzei
SMC Complexes: Methods and Protocols, 3-16, 2019
2019
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Articles 1–20