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Alen Krajnc
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Bicyclic boronate VNRX-5133 inhibits metallo-and serine-β-lactamases
A Krajnc, J Brem, P Hinchliffe, K Calvopiña, TD Panduwawala, PA Lang, ...
Journal of Medicinal Chemistry 62 (18), 8544-8556, 2019
1682019
The impact of COVID‐19 on the cancer care of adolescents and young adults and their well‐being: results from an online survey conducted in the early stages of the pandemic
U Košir, M Loades, J Wild, M Wiedemann, A Krajnc, S Roškar, L Bowes
Cancer 126 (19), 4414-4422, 2020
1102020
Will morphing boron-based inhibitors beat the β-lactamases?
A Krajnc, PA Lang, TD Panduwawala, J Brem, CJ Schofield
Current Opinion in Chemical Biology 50, 101-110, 2019
822019
Cyclic boronates as versatile scaffolds for KPC-2 β-lactamase inhibition
CL Tooke, P Hinchliffe, A Krajnc, AJ Mulholland, J Brem, CJ Schofield, ...
RSC medicinal chemistry 11 (4), 491-496, 2020
282020
Structural basis of prolyl hydroxylase domain inhibition by molidustat
WD Figg Jr, MA McDonough, R Chowdhury, Y Nakashima, Z Zhang, ...
ChemMedChem 16 (13), 2082-2088, 2021
262021
Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C β-Lactamase from Escherichia coli
PA Lang, A Parkova, TM Leissing, K Calvopiña, R Cain, A Krajnc, ...
Biomolecules 10 (6), 899, 2020
232020
Broad spectrum β-lactamase inhibition by a thioether substituted bicyclic boronate
A Parkova, A Lucic, A Krajnc, J Brem, K Calvopina, GW Langley, ...
ACS Infectious Diseases 6 (6), 1398-1404, 2019
202019
High-throughput crystallography reveals boron-containing inhibitors of a penicillin-binding protein with di-and tricovalent binding modes
H Newman, A Krajnc, D Bellini, CJ Eyermann, GA Boyle, NG Paterson, ...
Journal of Medicinal Chemistry 64 (15), 11379-11394, 2021
142021
What was the impact of COVID-19 on Adolescent and Young Adult cancer care and their wellbeing? Results from a cross-sectional online survey conducted in the early stages of the …
U Kosir, ME Loades, J Wild, M Wiedemann, A Krajnc, S Roškar, L Bowes
42020
Conjugates of monocyclic β-lactams and siderophore mimetics: a patent evaluation (WO2023023393)
A Krajnc, S Gobec
Expert opinion on therapeutic patents 33 (7-8), 471-476, 2023
12023
Reaction of nitrocefin with two serines of Pseudomonas aeruginosa penicillin-binding-protein 3
H Newman, D Bellini, A Krajnc, A Tumber, J Tod, A Lloyd, C Schofield, ...
2022
Synthesis and mechanistic analyses of boron-containing β-lactamase inhibitors
A Krajnc
University of Oxford, 2020
2020
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