The role of glutathione S-transferase GliG in gliotoxin biosynthesis in Aspergillus fumigatus C Davis, S Carberry, M Schrettl, I Singh, JC Stephens, SM Barry, ... Chemistry & Biology 18 (4), 542-552, 2011 | 99 | 2011 |
Metal-free “click” chemistry: efficient polymer modification via 1, 3-dipolar cycloaddition of nitrile oxides and alkynes I Singh, Z Zarafshani, JF Lutz, F Heaney Macromolecules 42 (15), 5411-5413, 2009 | 96 | 2009 |
Polycyclic aromatic DNA-base surrogates: high-affinity binding to an adenine-specific base-flipping DNA methyltransferase C Beuck, I Singh, A Bhattacharya, W Hecker, VS Parmar, O Seitz, ... Angewandte Chemie International Edition 42 (33), 3958-3960, 2003 | 94 | 2003 |
Efficient total syntheses and biological activities of two teixobactin analogues ETIS Anish Parmar, Abhishek Iyer, Charlotte Vincent, Dorien Van Lysebetten ... Chem. Commun., 10.1039/C5CC10249A, 2016 | 92* | 2016 |
Asymmetric PTC C-Alkylation Catalyzed by Chiral Derivatives of Tartaric Acid and Aminophenols. Synthesis of (R)- and (S)-α-Methyl Amino Acids YN Belokon, KA Kochetkov, TD Churkina, NS Ikonnikov, AA Chesnokov, ... The Journal of Organic Chemistry 65 (21), 7041-7048, 2000 | 88 | 2000 |
Design and Syntheses of Highly Potent Teixobactin Analogues against Staphylococcus aureus, Methicillin-Resistant Staphylococcus aureus (MRSA), and Vancomycin-Resistant … A Parmar, R Lakshminarayanan, A Iyer, V Mayandi, ET Leng Goh, ... Journal of medicinal chemistry 61 (5), 2009-2017, 2018 | 86 | 2018 |
Mode of action of teixobactins in cellular membranes R Shukla, J Medeiros-Silva, A Parmar, BJA Vermeulen, S Das, AL Paioni, ... Nature communications 11 (1), 2848, 2020 | 80 | 2020 |
Xanthones as inhibitors of microsomal lipid peroxidation and TNF-α induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs) B Madan, I Singh, A Kumar, AK Prasad, HG Raj, VS Parmar, B Ghosh Bioorganic & medicinal chemistry 10 (11), 3431-3436, 2002 | 72 | 2002 |
Designed thiazole orange nucleotides for the synthesis of single labelled oligonucleotides that fluoresce upon matched hybridization L Bethge, I Singh, O Seitz Organic & Biomolecular Chemistry 8 (10), 2439-2448, 2010 | 71 | 2010 |
Orthogonal, metal-free surface modification by strain-promoted azide–alkyne and nitrile oxide–alkene/alkyne cycloadditions C Wendeln, I Singh, S Rinnen, C Schulz, HF Arlinghaus, GA Burley, ... Chemical Science 3 (8), 2479-2484, 2012 | 63 | 2012 |
Solid phase strain promoted “click” modification of DNA via [3+ 2]-nitrile oxide–cyclooctyne cycloadditions I Singh, F Heaney Chemical communications 47 (9), 2706-2708, 2011 | 63 | 2011 |
Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding A Parmar, A Iyer, SH Prior, DG Lloyd, ETL Goh, CS Vincent, ... Chemical Science 8 (12), 8183-8192, 2017 | 58 | 2017 |
Diastereoselective Synthesis of β-Aryl-C-nucleosides from 1,2-Anhydrosugars I Singh, O Seitz Organic Letters 8 (19), 4319-4322, 2006 | 58 | 2006 |
Immobilization of hog pancreas lipase in macroporous poly (vinyl alcohol)-cryogel carrier for the biocatalysis in water-poor media FM Plieva, KA Kochetkov, I Singh, VS Parmar, YN Belokon', VI Lozinsky Biotechnology Letters 22, 551-554, 2000 | 58 | 2000 |
Defining the molecular structure of teixobactin analogues and understanding their role in antibacterial activities A Parmar, SH Prior, A Iyer, CS Vincent, D Van Lysebetten, E Breukink, ... Chemical communications 53 (12), 2016-2019, 2017 | 56 | 2017 |
Directed assembly of DNA-functionalized gold nanoparticles using pyrrole–imidazole polyamides Z Krpetic, I Singh, W Su, L Guerrini, K Faulds, GA Burley, D Graham Journal of the American Chemical Society 134 (20), 8356-8359, 2012 | 55 | 2012 |
Synthesis, characterization and in vitro anti-invasive activity screening of polyphenolic and heterocyclic compounds VS Parmar, NK Sharma, M Husain, AC Watterson, J Kumar, ... Bioorganic & medicinal chemistry 11 (6), 913-929, 2003 | 49 | 2003 |
Fast, copper-free click chemistry: a convenient solid-phase approach to oligonucleotide conjugation I Singh, JS Vyle, F Heaney Chemical communications, 3276-3278, 2009 | 48 | 2009 |
Teixobactin and its analogues: a new hope in antibiotic discovery WD Fiers, M Craighead, I Singh ACS infectious diseases 3 (10), 688-690, 2017 | 43 | 2017 |
Syntheses of potent teixobactin analogues against methicillin-resistant Staphylococcus aureus (MRSA) through the replacement of L-allo-enduracididine with its isosteres Parmar A, Iyer A, Lloyd DG, Vincent CS, Prior SH, Madder A, Taylor EJ, Singh I Chemical communications 53, 7788-7791, 2017 | 43 | 2017 |