Tom Dunkley
Tom Dunkley
Lab Head Mass Spectrometry, Roche Innovation Center Basel @ pRED
Verified email at
Cited by
Cited by
Mapping the Arabidopsis organelle proteome
TPJ Dunkley, S Hester, IP Shadforth, J Runions, T Weimar, SL Hanton, ...
Proceedings of the National Academy of Sciences 103 (17), 6518-6523, 2006
Localization of organelle proteins by isotope tagging (LOPIT)
TPJ Dunkley, R Watson, JL Griffin, P Dupree, KS Lilley
Molecular & Cellular Proteomics 3 (11), 1128-1134, 2004
i-Tracker: For quantitative proteomics using iTRAQ™
IP Shadforth, TPJ Dunkley, KS Lilley, C Bessant
BMC genomics 6 (1), 1-6, 2005
A systematic approach to modeling, capturing, and disseminating proteomics experimental data
CF Taylor, NW Paton, KL Garwood, PD Kirby, DA Stead, Z Yin, ...
Nature biotechnology 21 (3), 247-254, 2003
Growth control of the eukaryote cell: a systems biology study in yeast
JI Castrillo, LA Zeef, DC Hoyle, N Zhang, A Hayes, DCJ Gardner, ...
Journal of biology 6 (2), 1-25, 2007
Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics
N Nikolovski, D Rubtsov, MP Segura, GP Miles, TJ Stevens, TPJ Dunkley, ...
Plant physiology 160 (2), 1037-1051, 2012
Quantitative proteomic approach to study subcellular localization of membrane proteins
PG Sadowski, TPJ Dunkley, IP Shadforth, P Dupree, C Bessant, JL Griffin, ...
Nature protocols 1 (4), 1778-1789, 2006
mTORC1 inhibition corrects neurodevelopmental and synaptic alterations in a human stem cell model of tuberous sclerosis
V Costa, S Aigner, M Vukcevic, E Sauter, K Behr, M Ebeling, T Dunkley, ...
Cell reports 15 (1), 86-95, 2016
Targeted profiling of polar intracellular metabolites using ion-pair-high performance liquid chromatography and-ultra high performance liquid chromatography coupled to tandem …
F Michopoulos, N Whalley, G Theodoridis, ID Wilson, TPJ Dunkley, ...
Journal of Chromatography A 1349, 60-68, 2014
The use of isotope-coded affinity tags (ICAT) to study organelle proteomes in Arabidopsis thaliana
TPJ Dunkley, P Dupree, RB Watson, KS Lilley
Biochemical Society Transactions 32 (3), 520-523, 2004
AZD3514: A Small Molecule That Modulates Androgen Receptor Signaling and Function In Vitro and In VivoAZD3514 Modulates Androgen Receptor Signaling and Function
SA Loddick, SJ Ross, AG Thomason, DM Robinson, GE Walker, ...
Molecular cancer therapeutics 12 (9), 1715-1727, 2013
Improved sub‐cellular resolution via simultaneous analysis of organelle proteomics data across varied experimental conditions
MWB Trotter, PG Sadowski, TPJ Dunkley, AJ Groen, KS Lilley
Proteomics 10 (23), 4213-4219, 2010
Proteomics sample preparation
J von Hagen
John Wiley & Sons, 2008
Quantitative ADME proteomics–CYP and UGT enzymes in the beagle dog liver and intestine
AT Heikkinen, A Friedlein, M Matondo, OJD Hatley, A Petsalo, R Juvonen, ...
Pharmaceutical research 32 (1), 74-90, 2015
Confident protein identification using the average peptide score method coupled with search‐specific, ab initio thresholds
I Shadforth, T Dunkley, K Lilley, D Crowther, C Bessant
Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2005
MSstatsTMT: statistical detection of differentially abundant proteins in experiments with isobaric labeling and multiple mixtures
T Huang, M Choi, M Tzouros, S Golling, NJ Pandya, B Banfai, T Dunkley, ...
Molecular & Cellular Proteomics 19 (10), 1706-1723, 2020
N-Terminomics identifies HtrA1 cleavage of thrombospondin-1 with generation of a proangiogenic fragment in the polarized retinal pigment epithelial cell model of age-related …
C Chen, E Melo, P Jakob, A Friedlein, B Elsässer, P Goettig, V Kueppers, ...
Matrix Biology 70, 84-101, 2018
MassIVE. quant: a community resource of quantitative mass spectrometry–based proteomics datasets
M Choi, J Carver, C Chiva, M Tzouros, T Huang, TH Tsai, B Pullman, ...
Nature methods 17 (10), 981-984, 2020
Characterization of a human pluripotent stem cell‐derived model of neuronal development using multiplexed targeted proteomics
T Dunkley, V Costa, A Friedlein, S Lugert, S Aigner, M Ebeling, MT Miller, ...
PROTEOMICS–Clinical Applications 9 (7-8), 684-694, 2015
HtrA1 activation is driven by an allosteric mechanism of inter-monomer communication
AC Cabrera, E Melo, D Roth, A Topp, F Delobel, C Stucki, C Chen, ...
Scientific reports 7 (1), 1-11, 2017
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