| A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia B Button, LH Cai, C Ehre, M Kesimer, DB Hill, JK Sheehan, RC Boucher, ... Science 337 (6097), 937-941, 2012 | 852 | 2012 |
| Normal and cystic fibrosis airway surface liquid homeostasis: the effects of phasic shear stress and viral infections R Tarran, B Button, M Picher, AM Paradiso, CM Ribeiro, ER Lazarowski, ... Journal of Biological Chemistry 280 (42), 35751-35759, 2005 | 423 | 2005 |
| Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure AG Henderson, C Ehre, B Button, LH Abdullah, LH Cai, MW Leigh, ... The Journal of clinical investigation 124 (7), 3047-3060, 2014 | 340 | 2014 |
| Regulation of normal and cystic fibrosis airway surface liquid volume by phasic shear stress R Tarran, B Button, RC Boucher Annu. Rev. Physiol. 68, 543-561, 2006 | 300 | 2006 |
| A physical linkage between cystic fibrosis airway surface dehydration and Pseudomonas aeruginosa biofilms H Matsui, VE Wagner, DB Hill, UE Schwab, TD Rogers, B Button, ... Proceedings of the National Academy of Sciences 103 (48), 18131-18136, 2006 | 286 | 2006 |
| CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium L Zhang, B Button, SE Gabriel, S Burkett, Y Yan, MH Skiadopoulos, ... PLoS biology 7 (7), e1000155, 2009 | 230 | 2009 |
| Role of mechanical stress in regulating airway surface hydration and mucus clearance rates B Button, RC Boucher, University of North Carolina Virtual Lung Group Respiratory physiology & neurobiology 163 (1-3), 189-201, 2008 | 199 | 2008 |
| Differential effects of cyclic and constant stress on ATP release and mucociliary transport by human airway epithelia B Button, M Picher, RC Boucher The Journal of physiology 580 (2), 577-592, 2007 | 179 | 2007 |
| The relationship of mucus concentration (hydration) to mucus osmotic pressure and transport in chronic bronchitis WH Anderson, RD Coakley, B Button, AG Henderson, KL Zeman, ... American journal of respiratory and critical care medicine 192 (2), 182-190, 2015 | 160 | 2015 |
| Mechanosensitive ATP release maintains proper mucus hydration of airways B Button, SF Okada, CB Frederick, WR Thelin, RC Boucher Science signaling 6 (279), ra46-ra46, 2013 | 125 | 2013 |
| Pathological mucus and impaired mucus clearance in cystic fibrosis patients result from increased concentration, not altered pH DB Hill, RF Long, WJ Kissner, E Atieh, IC Garbarine, MR Markovetz, ... European Respiratory Journal 52 (6), 2018 | 121 | 2018 |
| Airway surface liquid pH is not acidic in children with cystic fibrosis A Schultz, R Puvvadi, SM Borisov, NC Shaw, I Klimant, LJ Berry, ... Nature communications 8 (1), 1409, 2017 | 107 | 2017 |
| IL-1β dominates the promucin secretory cytokine profile in cystic fibrosis G Chen, L Sun, T Kato, K Okuda, MB Martino, A Abzhanova, JM Lin, ... The Journal of clinical investigation 129 (10), 4433-4450, 2019 | 106 | 2019 |
| Physiology and pathophysiology of human airway mucus DB Hill, B Button, M Rubinstein, RC Boucher Physiological Reviews 102 (4), 1757-1836, 2022 | 101 | 2022 |
| Structure and function of the mucus clearance system of the lung BM Button, B Button Cold Spring Harbor perspectives in medicine 3 (8), a009720, 2013 | 99 | 2013 |
| Roles of mucus adhesion and cohesion in cough clearance B Button, HP Goodell, E Atieh, YC Chen, R Williams, S Shenoy, E Lackey, ... Proceedings of the National Academy of Sciences 115 (49), 12501-12506, 2018 | 96 | 2018 |
| Monitoring airway mucus flow and ciliary activity with optical coherence tomography AL Oldenburg, RK Chhetri, DB Hill, B Button Biomedical optics express 3 (9), 1978-1992, 2012 | 91 | 2012 |
| TMEM16A potentiation: a novel therapeutic approach for the treatment of cystic fibrosis HL Danahay, S Lilley, R Fox, H Charlton, J Sabater, B Button, C McCarthy, ... American journal of respiratory and critical care medicine 201 (8), 946-954, 2020 | 85 | 2020 |
| Mucus hyperconcentration as a unifying aspect of the chronic bronchitic phenotype B Button, WH Anderson, RC Boucher Annals of the American Thoracic Society 13 (Supplement 2), S156-S162, 2016 | 80 | 2016 |
| Burn resuscitation: crystalloid versus colloid versus hypertonic saline hyperoncotic colloid in sheep SC Guha, MP Kinsky, B Button, DN Herndon, LD Traber, DL Traber, ... Critical care medicine 24 (11), 1849-1857, 1996 | 77 | 1996 |
