Alastair Droop
Alastair Droop
Wellcome Sanger Institute
Verified email at - Homepage
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Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions
R Birnie, SD Bryce, C Roome, V Dussupt, A Droop, SH Lang, PA Berry, ...
Genome biology 9 (5), 1-13, 2008
Genomic subtypes of non-invasive bladder cancer with distinct metabolic profile and female gender bias in KDM6A mutation frequency
CD Hurst, O Alder, FM Platt, A Droop, LF Stead, JE Burns, GJ Burghel, ...
Cancer cell 32 (5), 701-715. e7, 2017
Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa
A Buskin, L Zhu, V Chichagova, B Basu, S Mozaffari-Jovin, D Dolan, ...
Nature communications 9 (1), 1-19, 2018
Prediction of clinical outcome in glioblastoma using a biologically relevant nine-microRNA signature
J Hayes, H Thygesen, C Tumilson, A Droop, M Boissinot, TA Hughes, ...
Molecular oncology 9 (3), 704-714, 2015
β-Catenin–mediated immune evasion pathway frequently operates in primary cutaneous melanomas
J Nsengimana, J Laye, A Filia, S O’Shea, S Muralidhar, J Poźniak, ...
The Journal of clinical investigation 128 (5), 2048-2063, 2018
Loss of CSL unlocks a hypoxic response and enhanced tumor growth potential in breast cancer cells
EB Braune, YL Tsoi, YP Phoon, S Landor, HS Cascales, D Ramsköld, ...
Stem cell reports 6 (5), 643-651, 2016
KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice
ES Polson, VB Kuchler, C Abbosh, EM Ross, RK Mathew, HA Beard, ...
Science translational medicine 10 (454), 2018
Retinoic acid and androgen receptors combine to achieve tissue specific control of human prostatic transglutaminase expression: a novel regulatory network with broader significance
GC Rivera-Gonzalez, AP Droop, HJ Rippon, K Tiemann, D Pellacani, ...
Nucleic acids research 40 (11), 4825-4840, 2012
Genetic and environmental determinants of immune response to cutaneous melanoma
J Poźniak, J Nsengimana, JP Laye, SJ O’Shea, JMS Diaz, AP Droop, ...
Cancer research 79 (10), 2684-2696, 2019
DNA hypermethylation in prostate cancer is a consequence of aberrant epithelial differentiation and hyperproliferation
D Pellacani, D Kestoras, AP Droop, FM Frame, PA Berry, MG Lawrence, ...
Cell Death & Differentiation 21 (5), 761-773, 2014
Engineering Simulations as Scientific Instruments: A Pattern Language: With Kieran Alden, Paul S. Andrews, James L. Bown, Alastair Droop, Richard B. Greaves, Mark Read, Adam T …
S Stepney, FAC Polack
Springer, 2018
The calcium sensor STIM1 is regulated by androgens in prostate stromal cells
PA Berry, R Birnie, AP Droop, NJ Maitland, AT Collins
The Prostate 71 (15), 1646-1655, 2011
Elucidating drivers of oral epithelial dysplasia formation and malignant transformation to cancer using RNAseq
C Conway, JL Graham, P Chengot, C Daly, R Chalkley, L Ross, A Droop, ...
Oncotarget 6 (37), 40186, 2015
The mutational signature profile of known and suspected human carcinogens in mice
L Riva, AR Pandiri, YR Li, A Droop, J Hewinson, MA Quail, V Iyer, ...
Nature genetics 52 (11), 1189-1197, 2020
Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma
HJ Close, LF Stead, J Nsengimana, KA Reilly, A Droop, H Wurdak, ...
Clinical & Experimental Immunology 200 (1), 33-44, 2020
Simulation validation: exploring the suitability of a simulation of cell division and differentiation in the prostate
FAC Polack, A Droop, P Garnett, T Ghetiu, S Stepney
Proceedings of the 2011 Workshop on Complex Systems Modelling and Simulation …, 2011
fqtools: an efficient software suite for modern FASTQ file manipulation
AP Droop
Bioinformatics 32 (12), 1883-1884, 2016
Prognostic microRNAs in high-grade glioma reveal a link to oligodendrocyte precursor differentiation
J Hayes, H Thygesen, A Droop, TA Hughes, D Westhead, SE Lawler, ...
Oncoscience 2 (3), 252, 2015
Multiple model simulation: modelling cell division and differentiation in the prostate
A Droop, P Garnett, FAC Polack, S Stepney
Proceedings of the 2011 Workshop on Complex Systems Modelling and Simulation …, 2011
A case-matched gender comparison transcriptomic screen identifies eIF4E and eIF5 as potential prognostic markers in male breast cancer
MP Humphries, SS Rajan, A Droop, CAB Suleman, C Carbone, C Nilsson, ...
Clinical Cancer Research 23 (10), 2575-2583, 2017
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